Zobrazeno 1 - 10
of 88
pro vyhledávání: '"David J. Sanger"'
Autor:
David J. Sanger, Derek E. Blackman
The study of drug effects on behaviour and psychological processes has a long history. Developments in the decade prior to first publication had been based on a more adequate synthesis than hitherto of psychology and pharmacology, and as a result gre
Autor:
David J. Sanger
Publikováno v:
CNS Drugs. 18:9-15
The new generation hypnotic drugs, zolpidem, zopiclone and zaleplon, are at least as efficacious in the clinic as benzodiazepines and may offer advantages in terms of safety. These drugs act through the BZ binding sites associated with GABAA receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d835ec7edb5bbd076e7c939f4cd1601
https://doi.org/10.2165/00023210-200418001-00004
https://doi.org/10.2165/00023210-200418001-00004
Publikováno v:
Neuropharmacology. 39:1848-1857
Compounds varying in selectivity as 5-HT(1A) receptor antagonists have recently been reported to produce benzodiazepine-like antianxiety effects in mice. To assess the cross-species generality of these findings, the present experiments compared the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccd9bba4198f3a99b434db1f3aa3de19
https://doi.org/10.1016/s0028-3908(00)00074-5
https://doi.org/10.1016/s0028-3908(00)00074-5
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 24:39-49
The restricted localization of dopamine (DA) D3 receptors in the rat cerebellum lobule 9/10 appears to provide a method for investigating the in vivo selectivity of dopaminergic compounds for the D3 receptor subtype. Sprague-Dawley rats implanted wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80bf408c46ed564686708f571032c189
https://doi.org/10.1016/s0278-5846(99)00079-2
https://doi.org/10.1016/s0278-5846(99)00079-2
Publikováno v:
Behavioural Pharmacology. 10:665-674
Nicotine improves cognitive performance both in animals and in humans, particularly in tests involving attentional processes. The five-choice serial reaction time task (5-CSRTT) is widely used as a model of attentional performance in rats, and previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee9cdab8e3a88dbc307a53f6fe142a4
https://doi.org/10.1097/00008877-199911000-00013
https://doi.org/10.1097/00008877-199911000-00013
Publikováno v:
Pharmacology Biochemistry and Behavior. 64:269-273
The GABA(A) receptor complex contains a number of binding sites at which a variety of psychotropic drugs, including benzodiazepines, barbiturates, and some neurosteroids, act to potentiate or inhibit the effect of the transmitter. Many studies have r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c6482665afff1282d7b63a9632f89e
https://doi.org/10.1016/s0091-3057(99)00081-7
https://doi.org/10.1016/s0091-3057(99)00081-7
Publikováno v:
Psychopharmacology. 144:121-130
Rationale: Compounds varying in selectivity as 5-HT1A receptor antagonists have recently been reported to produce anxiolytic-like effects comparable to those of benzodiazepines in the mouse elevated plus-maze procedure. Objective: In view of the pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3111718435cabb9614dc4c83a81ad683
https://doi.org/10.1007/s002130050984
https://doi.org/10.1007/s002130050984
Autor:
David J. Sanger, Paul Moser
Publikováno v:
European Journal of Pharmacology. 372:127-134
Recent clinical data suggest that coadministration of pindolol with an antidepressant, particularly the 5-hydroxytryptamine (5-HT) reuptake inhibitor fluoxetine, can shorten the time to onset of clinical activity and increase the proportion of respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa16e6112e405eb38016db63ac91a9c1
https://doi.org/10.1016/s0014-2999(99)00202-2
https://doi.org/10.1016/s0014-2999(99)00202-2
Publikováno v:
Pharmacology Biochemistry and Behavior. 62:689-694
The present experiments compared the behavioral effects of two novel BZ (ϖ) receptor agonists, the pyridazinone Y-23684 (1–30 mg/kg) and the pyrido[1,2-a]benzimidazole RWJ-46771 (0.01–0.3 mg/kg) with the BZs diazepam (0.5–3 mg/kg) and clobazam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d70e2c35cf623bb68dae2ab7666f58
https://doi.org/10.1016/s0091-3057(98)00209-3
https://doi.org/10.1016/s0091-3057(98)00209-3
Publikováno v:
Psychopharmacology. 142:221-229
Progressive-ratio (PR) schedules, which have been widely used to study the reinforcing efficacy of various reinforcers (in particular IV psychostimulants), have been very seldom applied to the study of positively reinforcing electrical brain stimulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c614ae937280d45b2f1e33747cbf395
https://doi.org/10.1007/s002130050883
https://doi.org/10.1007/s002130050883