Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David J. Sandgren"'
System for Scoring Severity of Acute Radiation Syndrome Response in Rhesus Macaques (Macaca mulatta)
Publikováno v:
Comparative Medicine. 68:474-488
We developed a clinical assessment tool for use in an NHP radiation model to 1) quantify severity responses for subsyndromes of the acute radiation syndrome (ARS; that is, hematopoietic and others) and 2) identify animals that required enhanced monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ce0d790640fa1aa9ce33f5596a67a4
https://doi.org/10.30802/aalas-cm-17-000106
https://doi.org/10.30802/aalas-cm-17-000106
Autor:
Donald P. Condliffe, Katya Krasnopolsky, Natalia I. Ossetrova, David J. Sandgren, Arifur Rahman, Patrick H. Ney, Kevin P. Hieber
Publikováno v:
Health Physics. 106:772-786
Nuclear accidents or terrorist attacks could expose large numbers of people to ionizing radiation. Early biomarkers of radiation injury will be critical for triage, treatment, and follow-up of such individuals. The authors evaluated the utility of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a851d988a43add86070cecacef0708
https://doi.org/10.1097/hp.0000000000000094
https://doi.org/10.1097/hp.0000000000000094
Publikováno v:
Radiation Protection Dosimetry. 159:46-51
This study evaluates both the effects of physical restraint and use of candidate biomarkers in a CD2F1 male mouse partial-body irradiation model for biological dosimetry diagnostic assays. Mice were irradiated (6-Gy, 250-kVp X ray) to 3/3rd (total bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185a0179d1067817ed9469738c64c4af
https://doi.org/10.1093/rpd/ncu127
https://doi.org/10.1093/rpd/ncu127
Publikováno v:
Radiation Measurements. 46:898-902
The objective of the present study was to establish a murine partial-body radiation exposure model for studies supporting the identification and validation of novel biological dosimetry diagnostic assays. A lead shielding – Plexiglas ® irradiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0edf4e3ea1a8cd028b36a0f877dddf46
https://doi.org/10.1016/j.radmeas.2011.05.006
https://doi.org/10.1016/j.radmeas.2011.05.006
Publikováno v:
Radiation Measurements. 46:1019-1024
Terrorist radiological attacks or nuclear accidents could expose large numbers of people to ionizing radiation. In mass-casualty radiological incidents early medical-management requires triage tools for first-responders to quantitatively identify ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da987692116fe86626cc5f7cbbfcbea3
https://doi.org/10.1016/j.radmeas.2011.05.021
https://doi.org/10.1016/j.radmeas.2011.05.021
Publikováno v:
Health Physics. 99:S184-S191
Effective and dynamic recording of radiation exposure and medical diagnostic information for individuals suspected or known to have been exposed to ionizing radiation contributes to appropriate formulation of medical treatment strategies and radiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a95d67922fd19a3fb197597fa9ced6
https://doi.org/10.1097/hp.0b013e3181f26895
https://doi.org/10.1097/hp.0b013e3181f26895
Autor:
Ira H. Levine, Patricia K. Lillis-Hearne, Charles A. Salter, James A. Ross, David J. Sandgren, William F. Blakely
Publikováno v:
Health Physics. 99:S171-S183
Medical management of suspected radiation casualties requires use of multiparameter biodosimetry because no single biodosimetric measurement is sufficiently robust. This report describes the design and algorithms used in a radiation exposure assessme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7134f45565561bb89b0df92a90decc38
https://doi.org/10.1097/hp.0b013e3181f0fe6c
https://doi.org/10.1097/hp.0b013e3181f0fe6c
Autor:
Marcy B. Grace, C. A. Salter, Natalia I. Ossetrova, William E. Jackson, William F. Blakely, Pataje G. S. Prasanna, David J Sandgren, G.L. Manglapus, Ira H. Levine, G.D. Ledney
Publikováno v:
Radiation Measurements. 42:1164-1170
Effective medical management of suspected radiation exposure incidents requires the recording of dynamic medical data (clinical signs and symptoms), biological assessments of radiation exposure, and physical dosimetry in order to provide diagnostic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d21fda2d8614299213290e48dc7e52bc
https://doi.org/10.1016/j.radmeas.2007.05.013
https://doi.org/10.1016/j.radmeas.2007.05.013
Autor:
David L. Bolduc, Rolf Bünger, David J. Sandgren, G. David Ledney, Vilmar Villa, William F. Blakely
Publikováno v:
Computational and Mathematical Methods in Medicine
Computational and Mathematical Methods in Medicine, Vol 2014 (2014)
Computational and Mathematical Methods in Medicine, Vol 2014 (2014)
Multivariate radiation injury estimation algorithms were formulated for estimating severe hematopoietic acute radiation syndrome (H-ARS) injury (i.e., response category three or RC3) in a rhesus monkey total-body irradiation (TBI) model. Classical CB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca03cf0fa03883f1af4dcc34cbed111
http://europepmc.org/articles/PMC4140144
http://europepmc.org/articles/PMC4140144
Publikováno v:
Radiation protection dosimetry. 159(1-4)
Development and validation of early-response radiation injury biomarkers are critical for effective triage and medical management of irradiated individuals. Plasma protein and haematological profiles were evaluated using multivariate linear-regressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe5c8061ce050af9c8b8c8906be3da7
https://pubmed.ncbi.nlm.nih.gov/24925901
https://pubmed.ncbi.nlm.nih.gov/24925901