Zobrazeno 1 - 10
of 62
pro vyhledávání: '"David J. Rademacher"'
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-14 (2023)
Abstract A severe complication of hematopoietic stem cell transplantation is graft-versus-host disease (GvHD), a reaction that occurs following the transfer of donor immune cells (the graft) into an allogeneic host. Transplanted cells recognize host
Externí odkaz:
https://doaj.org/article/85ad02c587d04006b7d73817c1d1aef6
Autor:
Juliana K. Choi, Samer A. Naffouje, Masahide Goto, Jing Wang, Konstantin Christov, David J. Rademacher, Albert Green, Arlene A. Stecenko, Ananda M. Chakrabarty, Tapas K. Das Gupta, Tohru Yamada
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A bidirectional interaction between Pseudomonas aeruginosa (PA) bacteria and cancerous tumors results in an anti-tumor effect; cancer cells stimulate PA-secretion of azurin which promotes tumor cell production of aldolase A.
Externí odkaz:
https://doaj.org/article/c00b7dc40e6f42159592b3df8c06fd59
Autor:
David J. Rademacher
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1187 (2023)
Pathogenic forms of α-synuclein (α-syn) are transferred to and from neurons, astrocytes, and microglia, which spread α-syn pathology in the olfactory bulb and the gut and then throughout the Parkinson’s disease (PD) brain and exacerbate neurodeg
Externí odkaz:
https://doaj.org/article/21b8979c4fc5451ebb9e7673b73c7e5b
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards R. Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1371 (2022)
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of act
Externí odkaz:
https://doaj.org/article/51f533a3d8a647a8b2b71052ec3441fa
Autor:
Kevin Burbidge, Virginia Zwikelmaier, Ben Cook, Michael M. Long, Barak Balva, Michael Lonigro, Grace Ispas, David J. Rademacher, Edward M. Campbell
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Extracellular vesicles (EVs) have been implicated in a wide variety of biological activities, have been implicated in the pathogenesis of numerous diseases, and have been proposed to serve as potential biomarkers of disease in human patients and anim
Externí odkaz:
https://doaj.org/article/4f7cf268e4a5457d9a3bfbe951b16303
Autor:
Timothy J. Collier, Jennifer O'Malley, David J. Rademacher, Jennifer A. Stancati, Kellie A. Sisson, Caryl E. Sortwell, Katrina L. Paumier, Kibrom G. Gebremedhin, Kathy Steece-Collier
Publikováno v:
Neurobiology of Disease, Vol 77, Iss , Pp 191-203 (2015)
Advanced age is the primary risk factor for Parkinson's disease (PD). In PD patients and rodent models of PD, advanced age is associated with inferior symptomatic benefit following intrastriatal grafting of embryonic dopamine (DA) neurons, a pattern
Externí odkaz:
https://doaj.org/article/237621f88f434677a865b0966fea3365
Autor:
Sachin Patel, Erica J. Carrier, W-S. Vanessa Ho, David J. Rademacher, Sonya Cunningham, D. Sudarshan Reddy, J.R. Falck, Benjamin F. Cravatt, Cecilia J. Hillard
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 2, Pp 342-349 (2005)
N-Arachidonylethanolamine (AEA) accumulates during brain injury and postmortem. Because fatty acid amide hydrolase (FAAH) regulates brain AEA content, the purpose of this study was to determine its role in the postmortal accumulation of AEA using FAA
Externí odkaz:
https://doaj.org/article/c9ea8a2248d94cb799eec95d07c1277d
Autor:
Alan J. Wolfe, David J. Rademacher, Carine R. Mores, Robert J. Evans, Tyler Overholt, Thomas Halverson, Roberto Limeira, Catherine Matthews, Gopal Badlani, Linda Brubaker, Stephen J. Walker
Publikováno v:
Journal of Urology. 209:937-949
Autor:
Juliana K, Choi, Samer A, Naffouje, Masahide, Goto, Jing, Wang, Konstantin, Christov, David J, Rademacher, Albert, Green, Arlene A, Stecenko, Ananda M, Chakrabarty, Tapas K, Das Gupta, Tohru, Yamada
Publikováno v:
Communications biology. 6(1)
Microorganisms living at many sites in the human body compose a complex and dynamic community. Accumulating evidence suggests a significant role for microorganisms in cancer, and therapies that incorporate bacteria have been tried in various types of
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Raman Mathur, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
SSRN Electronic Journal.