Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David J. Ottenheimer"'
Autor:
Kurt M. Fraser, Tabitha H. Kim, Matilde Castro, Céline Drieu, Yasmin Padovan-Hernandez, Bridget Chen, Fiona Pat, David J. Ottenheimer, Patricia H. Janak
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109652- (2024)
Summary: Dysregulation of the central amygdala is thought to underlie aberrant choice in alcohol use disorder, but the role of central amygdala neural activity during reward choice and consumption is unclear. We recorded central amygdala neurons in m
Externí odkaz:
https://doaj.org/article/8e4b1993bae74fdc8a5d828078a881e2
Autor:
Youna Vandaele, Nagaraj R Mahajan, David J Ottenheimer, Jocelyn M Richard, Shreesh P Mysore, Patricia H Janak
Publikováno v:
eLife, Vol 8 (2019)
Hypotheses of striatal orchestration of behavior ascribe distinct functions to striatal subregions, with the dorsolateral striatum (DLS) especially implicated in habitual and skilled performance. Thus neural activity patterns recorded from the DLS, b
Externí odkaz:
https://doaj.org/article/0aab6234936f4531a592056a10b8fbd3
Autor:
David J. Ottenheimer, Madelyn M. Hjort, Anna J. Bowen, Nicholas A. Steinmetz, Garret D. Stuber
SummaryThe ability to associate reward-predicting stimuli with adaptive behavior is frequently attributed to the prefrontal cortex, but the stimulus-specificity, spatial distribution, and stability of pre-frontal cue-reward associations are unresolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800e58e9235fadb86a01d1cb9fd6448c
https://doi.org/10.7554/elife.84604
https://doi.org/10.7554/elife.84604
Publikováno v:
eNeuro
For proper execution of goal-directed behaviors, individuals require both a general representation of the goal and an ability to monitor their own progress toward that goal. Here, we examine how dorsomedial striatum (DMS), a region pivotal for formin
For proper execution of goal-directed behaviors, individuals require both a general representation of the goal and an ability to monitor their own progress toward that goal. Here, we examine how dorsomedial striatum (DMS), a region pivotal for formin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab332950c8203e6ac9e75477965307a
https://doi.org/10.1101/2021.04.01.437899
https://doi.org/10.1101/2021.04.01.437899
Autor:
Karen Wang, David J. Ottenheimer, Jocelyn M. Richard, Xiao Tong, Patricia H. Janak, Kurt M. Fraser
Publikováno v:
Science advances, vol 6, iss 45
Science Advances
Science Advances
The brain’s ventral pallidum encodes reward preference across changing physiological state and influences reward decisions.
A key function of the nervous system is producing adaptive behavior across changing conditions, like physiological stat
A key function of the nervous system is producing adaptive behavior across changing conditions, like physiological stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e88890f2c6503e3c60fc50dad20756
https://escholarship.org/uc/item/5sq7h7vc
https://escholarship.org/uc/item/5sq7h7vc
Autor:
Jeremiah Y. Cohen, Tabitha H. Kim, Patricia H. Janak, David J. Ottenheimer, Elissa Sutlief, Bilal A. Bari, Kurt M. Fraser, Jocelyn M. Richard
Publikováno v:
Nature neuroscience, vol 23, iss 10
Nat Neurosci
Nat Neurosci
The nervous system is hypothesized to compute reward prediction errors (RPEs) to promote adaptive behavior. Correlates of RPEs have been observed in the midbrain dopamine system, but the extent to which RPE signals exist in other reward-processing re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bade92c750447756115aa3534e876a
https://escholarship.org/uc/item/2569b0c7
https://escholarship.org/uc/item/2569b0c7
Autor:
Bilal A. Bari, Jeremiah Y. Cohen, Jocelyn M. Richard, Tabitha H. Kim, Patricia H. Janak, Elissa Sutlief, David J. Ottenheimer, Kurt M. Fraser
Learning from past interactions with the environment is critical for adaptive behavior. Within the framework of reinforcement learning, the nervous system builds expectations about future reward by computing reward prediction errors (RPEs), the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb0c3001e577a5853d5490a90c1ddfa
Autor:
Patricia H. Janak, Alexandria Haimbaugh, David J. Ottenheimer, Karen Wang, Jocelyn M. Richard
Publikováno v:
Eur J Neurosci
A critical area of inquiry in the neurobiology of alcohol abuse is the mechanism by which cues gain the ability to elicit alcohol use. Previously, we found that cue-evoked activity in rat ventral pallidum robustly encodes the value of sucrose cues tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d916be6c37c674e0c416022d0b513b
https://europepmc.org/articles/PMC6848750/
https://europepmc.org/articles/PMC6848750/