Zobrazeno 1 - 10
of 33
pro vyhledávání: '"David J. Olivos"'
Autor:
Angela Bruzzaniti, Melissa A. Kacena, Ying Hua Cheng, Jung Min Hong, Christine M. Eischen, Robyn K. Fuchs, Lindsey D. Mayo, Daniel S. Perrien, R. Adam Hooker, David J. Olivos, Kristin T. Chun
Publikováno v:
Journal of Cellular Biochemistry. 119:8830-8840
Mouse double minute 2 (Mdm2) is a multifaceted oncoprotein that is highly regulated with distinct domains capable of cellular transformation. Loss of Mdm2 is embryonically lethal, making it difficult to study in a mouse model without additional genet
Autor:
Yasaman Shirazi-Fard, Cynthia-May S. Gong, Sungshin Y. Choi, David C. Scofield, David J. Olivos, Jonathan S. Harris, Paul Childress, Todd O. McKinley, Rasha Hammamieh, Alexander Brinker, Carolynn L. Conley, Tien-Min G. Chu, Melissa A. Kacena, Nabarun Chakraborty, Jeffrey D. Rytlewski
Publikováno v:
Life Sciences in Space Research. 16:52-62
Segmental bone defects (SBDs) secondary to trauma invariably result in a prolonged recovery with an extended period of limited weight bearing on the affected limb. Soldiers sustaining blast injuries and civilians sustaining high energy trauma typify
Autor:
Ying-Hua Cheng, Robyn K. Fuchs, Haley McGough, David J. Olivos, Pierre P. Eleniste, Richard Adam Hooker, Marta Alvarez, Edward F. Srour, Mark C. Horowitz, Christopher Yim, Wendy A. Ciovacco, Monique Bethel, Angela Bruzzaniti, Brahmananda R. Chitteti, Melissa A. Kacena
Publikováno v:
Journal of Cellular Biochemistry. 118:2231-2240
The Lnk adapter protein negatively regulates the signaling of thrombopoietin (TPO), the main megakaryocyte (MK) growth factor. Lnk-deficient (-/-) mice have increased TPO signaling and increased MK number. Interestingly, several mouse models exist in
Autor:
Tien-Min G. Chu, Izath Nizeet Aguilar, David J. Olivos, Alexander Brinker, Diane R. Wagner, Marta B. Alvarez, Melissa A. Kacena, Lester J. Smith
Publikováno v:
Bioprinting (Amsterdam, Netherlands). 15
Limitations in scaffold material properties, such as sub-optimal degradation time, highlight the need for alternative approaches to engineer de novo tissues. One emerging solution for fabricating tissue constructs is scaffold-free tissue engineering.
Publikováno v:
Oncotarget
Mouse double minute 2 (Mdm2) and MdmX dimerize in response to low levels of genotoxic stress to function in a ubiquitinating complex, which signals for destabilization of p53. Under growth conditions, Mdm2 functions as a neddylating ligase, but the i
Autor:
Mary Saunders, Amir Sahabi, David J. Olivos, Randy P. Carney, Lin Tian, Yann Thillier, Zsofia Kiss, Alisha Knudson, Ruiwu Liu, Kit S. Lam, Jean Carlos Heleno Campos
Publikováno v:
ACS combinatorial science, vol 19, iss 5
Membrane active peptides (MAPs) represent a class of short biomolecules that have shown great promise in facilitating intracellular delivery without disrupting cellular plasma membranes. Yet their clinical application has been stalled by numerous fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f022bca15c037af8b8d6410c0e2fb05
https://europepmc.org/articles/PMC5901688/
https://europepmc.org/articles/PMC5901688/
Autor:
David J, Olivos, Marta, Alvarez, Ying-Hua, Cheng, Richard Adam, Hooker, Wendy A, Ciovacco, Monique, Bethel, Haley, McGough, Christopher, Yim, Brahmananda R, Chitteti, Pierre P, Eleniste, Mark C, Horowitz, Edward F, Srour, Angela, Bruzzaniti, Robyn K, Fuchs, Melissa A, Kacena
Publikováno v:
Journal of cellular biochemistry. 118(8)
The Lnk adapter protein negatively regulates the signaling of thrombopoietin (TPO), the main megakaryocyte (MK) growth factor. Lnk-deficient (−/−) mice have increased TPO signaling and increased MK number. Interestingly, several mouse models exis
Autor:
Diane R. Wagner, Tien-Min G. Chu, Lester J. Smith, David J. Olivos, Izath Nizeet Aguilar, Melissa A. Kacena
Publikováno v:
Bioprinting
The Kenzan bioprinting method provides a high-resolution biofabrication process by facilitating the fusion of submillimeter cell aggregates (spheroids) into larger tissue constructs on a needle array that is removed upon spheroid fusion. Although the
Publikováno v:
Cancer Research. 77:2552-2552
Cell fusion is a physiological process utilized by a variety of biological systems during fertilization, embryogenesis, and cellular differentiation and morphogenesis. During the malignant transformation of breast and bone tissues, normal and maligna
Autor:
David J. Olivos, Lindsey D. Mayo
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 12, p 1982 (2016)
International Journal of Molecular Sciences, Vol 17, Iss 12, p 1982 (2016)
Since its discovery nearly 40 years ago, p53 has ascended to the forefront of investigated genes and proteins across diverse research disciplines and is recognized most exclusively for its role in cancer as a tumor suppressor. Levine and Oren (2009)