Zobrazeno 1 - 10
of 13
pro vyhledávání: '"David J. Miner"'
Autor:
Peter T. Kissinger, David J. Miner
Publikováno v:
Biochemical Pharmacology. 28:3285-3290
Evidence for the presence of N -acetyl- p -quinoneimine (NAPQI), a postulated toxic intermediate of acetaminophen metabolism, in mouse liver microsomal incubations is reported. The intermediate was tentatively identified by comparison with synthetic
Publikováno v:
American Journal of Kidney Diseases. 10:306-313
Of patients who developed end-stage renal disease secondary to sickle cell anemia (SCA), some have undergone renal transplantation with reasonable success. We recently cared for a patient with SCA and a functioning, transplanted kidney who experience
Publikováno v:
Analytical Chemistry. 53:2258-2263
Autor:
David J. Miner, Ronald J. Bopp
Publikováno v:
Journal of Pharmaceutical Sciences. 71:1402-1406
A simple and specific method has been developed for determination of enviroxime in biological samples. Enviroxime, a substituted benzimidazole, its coisomer zinviroxime, and the internal standard hexestrol were extracted from the samples with benzene
Autor:
Thomas C. Hardin, Dennis L. Coleman, David J. Miner, Alexander M. M. Shepherd, Thomas M. Ludden
Publikováno v:
Journal of Antimicrobial Chemotherapy. 12:377-386
Pharmacokinetic parameters were calculated from plasma and urine latamoxef ('Moxalactam') levels determined by HPLC assay after single and multiple intramuscular (im) and single intravenous (iv) doses of 500 mg given to eight healthy volunteers. Afte
Autor:
David J. Miner
Publikováno v:
Analytica Chimica Acta. 134:101-109
The temperature dependence of amperometric response to compounds commonly assayed by liquid chromatography with electrochemical detection is reported. Temperature dependence ranges from 1.5 to 9% change in response per degree. Both diffusion and hete
Publikováno v:
Antimicrobial Agents and Chemotherapy. 20:252-257
High-performance liquid chromatographic methods for determination of the isomers of moxalactam in plasma and urine have been developed. Conventional reverse-phase chromatography was used for plasma assays, and an ion-pairing reagent was included for
Autor:
Peter T. Kissinger, David J. Miner
Publikováno v:
Analytica Chimica Acta. 138:231-235
The oxidation of soterenol and subsequent reaction of the substituted o-quinoneimine in acidic media were studied by cyclic voltammetry, flow-through coulometry, liquid chromatography combined with electrochemistry and fluorescence spectroscopy. The
Publikováno v:
Analytical Letters. 12:213-217
A stationary-solution voltammetry cell using a unique geometry for electrode placement is described. Semimicro working and auxiliary electrodes are contained in a small sample compartment, which is isolated from a larger reference compartment by a po
Publikováno v:
Journal of Pharmaceutical Sciences. 74:846-850
A rapid and specific high-performance liquid chromatographic (HPLC) assay has been developed for the determination of enviradene, 1, at concentrations of 2-5 ng/mL in plasma. The drug was extracted from the samples using benzene. The benzene extract