Zobrazeno 1 - 10
of 186
pro vyhledávání: '"David J. Milan"'
Autor:
Jun Jie Tan, Jacques P. Guyette, Kenji Miki, Ling Xiao, Gurbani Kaur, Tong Wu, Liye Zhu, Katrina J. Hansen, King-Hwa Ling, David J. Milan, Harald C. Ott
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The authors form pre-epicardial cells (PECs) from hiPSC-derived lateral plate mesoderm on treating with BMP4, RA and VEGF, and co-culture these PECs with cardiomyocytes, inducing cardiomyocyte aggregation, proliferation and network formation with mor
Externí odkaz:
https://doaj.org/article/dce68985cbe8407fb378c24f42d8af61
Publikováno v:
Remote Sensing, Vol 12, Iss 11, p 1799 (2020)
One potential Natural Flood Management (NFM) option is floodplain reforestation or manage existing riparian forests, with a view to increasing flow resistance and attenuate flood hydrographs. However, the effectiveness of floodplain forests as resist
Externí odkaz:
https://doaj.org/article/237bdf1698564f819259504db1958f76
Publikováno v:
HeartRhythm Case Reports, Vol 2, Iss 4, Pp 280-282 (2016)
Externí odkaz:
https://doaj.org/article/64d189e57b94490db12d61770a6b0154
Autor:
Jordan S. Leyton-Mange, Robert W. Mills, Vincenzo S. Macri, Min Young Jang, Faraz N. Butte, Patrick T. Ellinor, David J. Milan
Publikováno v:
Stem Cell Reports, Vol 2, Iss 2, Pp 163-170 (2014)
In addition to their promise in regenerative medicine, pluripotent stem cells have proved to be faithful models of many human diseases. In particular, patient-specific stem cell-derived cardiomyocytes recapitulate key features of several life-threate
Externí odkaz:
https://doaj.org/article/279e7a5e797148158615c7e16a830fbd
Autor:
Aneesh Bapat, Maximilian J. Schloss, Masahiro Yamazoe, Jana Grune, Maarten Hulsmans, David J. Milan, Matthias Nahrendorf, Patrick T. Ellinor
Publikováno v:
Circulation. 147:1047-1049
Autor:
Jana, Grune, Andrew J M, Lewis, Masahiro, Yamazoe, Maarten, Hulsmans, David, Rohde, Ling, Xiao, Shuang, Zhang, Christiane, Ott, David M, Calcagno, Yirong, Zhou, Kerstin, Timm, Mayooran, Shanmuganathan, Fadi E, Pulous, Maximilian J, Schloss, Brody H, Foy, Diane, Capen, Claudio, Vinegoni, Gregory R, Wojtkiewicz, Yoshiko, Iwamoto, Tilman, Grune, Dennis, Brown, John, Higgins, Vanessa M, Ferreira, Neil, Herring, Keith M, Channon, Stefan, Neubauer, David E, Sosnovik, David J, Milan, Filip K, Swirski, Kevin R, King, Aaron D, Aguirre, Patrick T, Ellinor, Matthias, Nahrendorf
Publikováno v:
Nature Cardiovascular Research. 1:649-664
Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in patients with coronary heart disease. Myocardial ischemia simultaneously induces arrhythmia and massive myocardial leukocyte changes. In this study, we optimized
Autor:
Carolina Roselli, Mengyao Yu, Victor Nauffal, Adrien Georges, Qiong Yang, Katie Love, Lu Chen Weng, Francesca N Delling, Svetlana R Maurya, Maren Schrölkamp, Jacob Tfelt-Hansen, Albert Hagège, Xavier Jeunemaitre, Stéphanie Debette, Philippe Amouyel, Wyliena Guan, Jochen D Muehlschlegel, Simon C Body, Svati Shah, Zainab Samad, Sergiy Kyryachenko, Carol Haynes, Michiel Rienstra, Thierry Le Tourneau, Vincent Probst, Ronan Roussel, Inez J Wijdh-Den Hamer, Joylene E Siland, Kirk U Knowlton, Jean Jacques Schott, Robert A Levine, Emelia J Benjamin, Ramachandran S Vasan, Benjamin D Horne, Joseph B Muhlestein, Giovanni Benfari, Maurice Enriquez-Sarano, Andrea Natale, Sanghamitra Mohanty, Chintan Trivedi, Moore B Shoemaker, Zachary T Yoneda, Quinn S Wells, Michael T Baker, Eric Farber-Eger, Hector I Michelena, Alicia Lundby, Russell A Norris, Susan A Slaugenhaupt, Christian Dina, Steven A Lubitz, Nabila Bouatia-Naji, Patrick T Ellinor, David J Milan
Publikováno v:
Eur Heart J
European Heart Journal, 43(17), 1668-1680. Oxford University Press
European Heart Journal, 43(17), 1668-1680. Oxford University Press
AIMS: Mitral valve prolapse (MVP) is a common valvular heart disease with a prevalence of >2% in the general adult population. Despite this high incidence, there is a limited understanding of the molecular mechanism of this disease, and no medical th
Autor:
David J. Milan
Publikováno v:
Progress in Physical Geography: Earth and Environment. 46:124-151
In July 2007 an intense summer storm resulted in significant activation of the sediment system in the Thinhope Burn, UK. Catchment- and reach-scale morphodynamic modelling is used to investigate the geomorphic work undertaken by Thinhope Burn; compar
Autor:
David J. Milan, Arved C. Schwendel
Publikováno v:
Earth Surface Processes and Landforms. 46:3026-3044
Upland river systems in the UK are predicted to be prone to the effects of increased flood magnitudes and frequency, driven by climate change. It is clear from recent events that some headwater catchments can be very sensitive to large floods, activa
Autor:
Harald C. Ott, Jacques P. Guyette, Gurbani Kaur, Ling Xiao, Katrina J. Hansen, King Hwa Ling, David J. Milan, Jun Jie Tan, Tong Wu, Liye Zhu, Kenji Miki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Epicardial formation is necessary for normal myocardial morphogenesis. Here, we show that differentiating hiPSC-derived lateral plate mesoderm with BMP4, RA and VEGF (BVR) can generate a premature form of epicardial cells (termed pre-epicardial cells