Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David J. Lomb"'
Autor:
Alp Ozgun, David J. Lomboni, Amy Aylsworth, Allison Macdonald, William A. Staines, Marzia Martina, Michael G. Schlossmacher, Joseph S. Tauskela, John Woulfe, Fabio Variola
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100992- (2024)
Modern in vitro technologies for preclinical research, including organ-on-a-chip, organoids- and assembloid-based systems, have rapidly emerged as pivotal tools for elucidating disease mechanisms and assessing the efficacy of putative therapeutics. I
Externí odkaz:
https://doaj.org/article/d2bae2e1d0ce40cf9af33ace061c32c7
Publikováno v:
Cell. 137(3)
SummarySirtuins are NAD-dependent protein deacetylases that connect metabolism and aging. In mammals, there are seven sirtuins (SIRT1-7), three of which are associated with mitochondria. Here, we show that SIRT5 localizes in the mitochondrial matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a23abd405b710c80a9146b1b6f620d3
https://pubmed.ncbi.nlm.nih.gov/19410538
https://pubmed.ncbi.nlm.nih.gov/19410538
Publikováno v:
Journal of neurochemistry. 103(5)
Nerve growth factor (NGF) serves a critical survival-promoting function for developing sympathetic neurons. Following removal of NGF, sympathetic neurons undergo apoptosis characterized by the activation of c-Jun N-terminal kinases (JNKs), up-regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f10b9f55645e1ae69fe55386f63833c
https://pubmed.ncbi.nlm.nih.gov/17760870
https://pubmed.ncbi.nlm.nih.gov/17760870
Autor:
Liang Xie, Robert S. Freeman, Robert J. Crowder, Matthew C Schoell, David J. Lomb, Jennifer A. Straub, Robert L Burch
Nerve growth factor (NGF) is required for the survival of developing sympathetic and sensory neurons. In the absence of NGF, these neurons undergo protein synthesis-dependent apoptosis. Ten years have gone by since the first reports of specific genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87960983ea891df5894f568063af9970
https://doi.org/10.1016/s0079-6123(03)46008-1
https://doi.org/10.1016/s0079-6123(03)46008-1
Autor:
Robert S, Freeman, Robert L, Burch, Robert J, Crowder, David J, Lomb, Matthew C, Schoell, Jennifer A, Straub, Liang, Xie
Publikováno v:
Progress in brain research. 146
Nerve growth factor (NGF) is required for the survival of developing sympathetic and sensory neurons. In the absence of NGF, these neurons undergo protein synthesis-dependent apoptosis. Ten years have gone by since the first reports of specific genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fafd6ee9c4aa0531591993ead31c27c5
https://pubmed.ncbi.nlm.nih.gov/14699960
https://pubmed.ncbi.nlm.nih.gov/14699960