Zobrazeno 1 - 10
of 181
pro vyhledávání: '"David J. Grdina"'
Autor:
Aris T. Alexandrou, Yixin Duan, Shanxiu Xu, Clifford Tepper, Ming Fan, Jason Tang, Jonathan Berg, Wassim Basheer, Tyler Valicenti, Paul F. Wilson, Matthew A. Coleman, Andrew T. Vaughan, Loning Fu, David J. Grdina, Jefferey Murley, Aijun Wang, Gayle Woloschak, Jian Jian Li
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105546- (2022)
Summary: During evolution, humans are acclimatized to the stresses of natural radiation and circadian rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive radioprotection can be induced by pre-exposure to low-l
Externí odkaz:
https://doaj.org/article/ab4b1bb439934bffa428c50b441d4e4b
Autor:
Demet Candas-Green, Bowen Xie, Jie Huang, Ming Fan, Aijun Wang, Cheikh Menaa, Yanhong Zhang, Lu Zhang, Di Jing, Soheila Azghadi, Weibing Zhou, Lin Liu, Nian Jiang, Tao Li, Tianyi Gao, Colleen Sweeney, Rulong Shen, Tzu-yin Lin, Chong-xian Pan, Omer M. Ozpiskin, Gayle Woloschak, David J. Grdina, Andrew T. Vaughan, Ji Ming Wang, Shuli Xia, Arta M. Monjazeb, William J. Murphy, Lun-Quan Sun, Hong-Wu Chen, Kit S. Lam, Ralph R. Weichselbaum, Jian Jian Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The emergence of tumour adaptive radioresistance can limit the success of radiation therapy and immunotherapy in breast cancer. In this study, the authors demonstrate that CD47 and HER2 are coordinating in tumor response to radiation and that co-bloc
Externí odkaz:
https://doaj.org/article/278b23d810204e89b5b3f18e5d760fef
Autor:
Lili Qin, Ming Fan, Demet Candas, Guochun Jiang, Stelios Papadopoulos, Lin Tian, Gayle Woloschak, David J. Grdina, Jian Jian Li
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2056-2063 (2015)
Nuclear DNA repair capacity is a critical determinant of cell fate under genotoxic stress conditions. DNA repair is a well-defined energy-consuming process. However, it is unclear how DNA repair is fueled and whether mitochondrial energy production c
Externí odkaz:
https://doaj.org/article/58e9bd3731244068bf718487fee47e05
Autor:
David J. Grdina
Publikováno v:
Holland‐Frei Cancer Medicine. :1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a4edec54537e3db35c1e65a2ca08a1
https://doi.org/10.1002/9781119000822.hfcm025.pub2
https://doi.org/10.1002/9781119000822.hfcm025.pub2
Autor:
Ralph R. Weichselbaum, Gayle E. Woloschak, Jian Jian Li, Harold G. Sutton, Helena J. Mauceri, Richard C. Miller, Jeffrey S. Murley, David J. Grdina
PDF - 186K, Representative TUNEL assay images of RKO36 apoptotic cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::358828707db5a259a96c0e37e895c2a2
https://doi.org/10.1158/0008-5472.22395008.v1
https://doi.org/10.1158/0008-5472.22395008.v1
Autor:
Jeffrey S. Murley, David J. Grdina
Publikováno v:
Radioprotectors ISBN: 9781003068181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cc45e49fb019ec2231532659fbae3bd
https://doi.org/10.4324/9781003068181-17
https://doi.org/10.4324/9781003068181-17
Autor:
David J. Grdina
Publikováno v:
Radiation Biology ISBN: 9780429279034
The treatment of solid tumors with ionizing radiation dates to as early as 1896 when it was reported that a patient with carcinoma of the breast was treated with X-rays. The rationale for employing cell separation techniques in the study of tumor-rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67b5109ee934acef47ca843efbae881
https://doi.org/10.4324/9780429279034-6
https://doi.org/10.4324/9780429279034-6
Publikováno v:
Free radical biologymedicine. 123
The survivin-associated radio-adaptive response can be induced following exposure to ionizing radiation in the dose range from 5 to 100 mGy, and its magnitude of expression is dependent upon the TP53 mutational status of cells and ROS signaling. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbf3e6364a2a1ca29508d374f6c2f76
https://pubmed.ncbi.nlm.nih.gov/29660403
https://pubmed.ncbi.nlm.nih.gov/29660403
Publikováno v:
Radiation research. 188(5)
A survivin-associated radio-adaptive response, characterized by increased radiation resistance or sensitization, was induced by exposure to 5 mGy of ionizing radiation and was correlated to the TP53 mutational status of exposed cells. Ten human cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecaee2626af4f9461ce291f98028e15
https://pubmed.ncbi.nlm.nih.gov/28813624
https://pubmed.ncbi.nlm.nih.gov/28813624