Zobrazeno 1 - 10
of 50
pro vyhledávání: '"David J. Graves"'
Publikováno v:
Polymers. 14(9)
Among the new molecular tools available to scientists and engineers, some of the most useful include fluorescently tagged biomolecules. Tools, such as green fluorescence protein (GFP), have been applied to perform semi-quantitative studies on biologi
Autor:
David J. Graves
Publikováno v:
Preparative and Production Scale Chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e3aa9deb65af09a3456986a79fab35
https://doi.org/10.1201/9780367811150-12
https://doi.org/10.1201/9780367811150-12
Autor:
Jason Y. Park, Larry J. Kricka, Naomi J. Halas, Terry Hyslop, David J. Graves, Paolo Fortina, Scott A. Waldman, Felicia Tam, Saul Surrey
Publikováno v:
Trends in Biotechnology. 25:145-152
Nanotechnology has considerable promise for the detection, staging and treatment of cancer. Here, we outline one such promising application: the use of nanostructures with surface-bound ligands for the targeted delivery and ablation of colorectal can
Publikováno v:
Biophysical Journal. 89(5):2950-2959
Although the kinetics of hybridization between a soluble polynucleotide and an immobilized complementary sequence have been studied by others, it is almost universally assumed that the interaction between each probe/target pair can be treated as a se
Publikováno v:
Langmuir. 19:10317-10323
Oligonucleotides are unique chemical moieties that can serve as a useful assembly tool. Unlike most bioadhesion molecules that bind together with high affinity, the attraction between complementary DNA strands can vary greatly depending on strand cha
Publikováno v:
Langmuir. 19:6905-6911
The hybridization of complementary DNA chains can be used to identify unknown strands. Substantial work has been done to link nanoparticles in solution or on surfaces via DNA hybridization. However, few studies have been done on micron-sized particle
Publikováno v:
BioTechniques. 32:346-354
We have constructed a confocal scanner suitable for routine microarray analysis from commercially available parts. We have outlined the details that should be considered when designing such an instrument and listed some of the specific components com
Autor:
David J. Graves
Publikováno v:
Trends in Biotechnology. 17:127-134
Microscopic arrays of oligonucleotides or cDNA containing up to several hundred thousand different sequences are starting to influence methodologies and paths to discovery in genomics. Gene polymorphisms and mutations can be found and gene expression
Publikováno v:
Analytical Chemistry. 70:5085-5092
We describe the construction and operation of an arrayer system to produce patterns of DNA sequences for analytical uses such as microarrays of oligonucleotide on microchips. Detailed documentation on construction is provided, as well as added electr
Publikováno v:
Biophysical Journal. 69:2243-2255
A mathematical model based on receptor-ligand interactions at a cell surface has been modified and further developed to represent heterogeneous DNA-DNA hybridization on a solid surface. The immobilized DNA molecules with known sequences are called pr