Zobrazeno 1 - 10
of 113
pro vyhledávání: '"David J. Gallagher"'
Autor:
Robert F. Power, Damien E. Doherty, Roberta Horgan, Pat Fahey, David J. Gallagher, Maeve A. Lowery, Karen A. Cadoo
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background Lynch syndrome is the most common cause of hereditary colorectal and endometrial cancer. Lifestyle modification may provide an opportunity for adjunctive cancer prevention. In this study, we aimed to characterise modifiable risk f
Externí odkaz:
https://doaj.org/article/d66eaffb320143358fda5da9460382f0
Publikováno v:
Natural Sciences, Vol 2, Iss 4, Pp n/a-n/a (2022)
Abstract Electrocatalysts that start a reaction as molecules do not always end the reaction as molecules, and even when they do, they might not be molecules during catalysis. In this Perspective, we discuss knowledge learned from the study of Cu‐ba
Externí odkaz:
https://doaj.org/article/4aab2ae4cb3c4d9fa8b481e8b13d1232
Autor:
Philip D. Mc Entee, Poorya Shokuhi, Ailin C. Rogers, Brian J. Mehigan, Paul H. McCormick, Charles M. Gillham, M. John Kennedy, David J. Gallagher, Ciara E. Ryan, Cian B. Muldoon, John O. Larkin
Publikováno v:
European Journal of Surgical Oncology. 48:1638-1642
Colorectal cancer (CRC) outcomes vary depending on tumour biology, with several features used to predict disease behaviour. Extramural venous invasion (EMVI) is associated with negative outcomes and its presence has been established as an indicator o
Autor:
Bo Shang, Conor L. Rooney, David J. Gallagher, Bernie T. Wang, Andrey Krayev, Hadar Shema, Oliver Leitner, Nia J. Harmon, Langqiu Xiao, Colton Sheehan, Samuel R. Bottum, Elad Gross, James F. Cahoon, Thomas E. Mallouk, Hailiang Wang
Publikováno v:
Angewandte Chemie. 135
We report a precious-metal-free molecular catalyst-based photocathode that is active for aqueous CO2 reduction to CO and methanol. The photoelectrode is composed of cobalt phthalocyanine molecules anchored on graphene oxide and integrated via a (3-am
Uptake of BRCA1/BRCA2 predictive genetic testing in an Irish population is low: a missed opportunity
Autor:
David E. O’Reilly, Lucy Dooley, Geoffrey A. Watson, Roisin Clarke, Amy Nolan, Carmel Nolan, Eileen Berkeley, Michael Farrell, Trudi McDevitt, Melissa Rogers, Catherine Clabby, David J. Gallagher
Publikováno v:
Irish Journal of Medical Science (1971 -).
Predictive testing for BRCA1 or BRCA2 allows at-risk individuals to engage with appropriate screening and treatment services if a pathogenic mutation is identified. Previous studies have shown uptake of predictive testing to most commonly range betwe
Autor:
Alice Talbot, Eileen Berkley, Roisin Clarke, Emily O'Donovan, David J. Gallagher, Carmel Nolan
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cancer
BMC Cancer
Background Lynch syndrome (LS) is an autosomal dominant hereditary cancer syndrome responsible for 2–4% of hereditary colorectal cancers (CRC). Mismatch repair protein deficiency (dMMR) is a characteristic feature of LS. It has been associated with
Publikováno v:
Natural Sciences. 2
Autor:
Terri Patricia McVeigh, Karl J. Sweeney, Donal J. Brennan, Una M. McVeigh, Simon Ward, Ann Strydom, Sheila Seal, Katherine Astbury, Paul Donnellan, Joanne Higgins, Maccon Keane, Michael J. Kerin, Carmel Malone, Pauline McGough, Ray McLaughlin, Michael O’Leary, Margaret Rushe, Michael Kevin Barry, Geraldine MacGregor, Michael Sugrue, Ala Yousif, Dhafir Al-Azawi, Eileen Berkeley, Terence J. Boyle, Elizabeth M. Connolly, Carmel Nolan, Elaine Richardson, Claire Giffney, Samantha B. Doyle, Sheila Broderick, William Boyd, Ruaidhri McVey, Thomas Walsh, Michael Farrell, David J. Gallagher, Nazneen Rahman, Angela J. George
Publikováno v:
Familial cancer.
In the Republic of Ireland (ROI), BRCA1/BRCA2 genetic testing has been traditionally undertaken in eligible individuals, after pre-test counselling by a Clinical Geneticist/Genetic Counsellor. Clinical Genetics services in ROI are poorly resourced, w
Autor:
Erin E. Salo-Mullen, Liying Zhang, David J. Gallagher, Vikas Rai, Magan Trottier, Yirong Li, Michael P. Farrell, Zsofia K. Stadler, Heleen M. van der Klift, Ciyu Yang
Publikováno v:
Genes, chromosomescancerREFERENCES. 60(8)
Germline mutations in the DNA mismatch repair (MMR) genes cause Lynch syndrome (LS). In this study, we identified and characterized a novel SINE-VNTR-Alu (SVA) insertion in exon 12 of MSH2 in an individual with early-onset colorectal cancer and a ver
Autor:
David J. Gallagher, Vikas Rai, Michael P. Farrell, Yirong Li, Magan Trottier, Erin E. Salo-Mullen, Liying Zhang, Heleen M. van der Klift, Zsofia K. Stadler, Ciyu Yang
Germline mutations in the DNA mismatch repair (MMR) genes cause Lynch syndrome (LS). Insertions of retrotransposons in MMR genes have been reported as a rare cause of LS. Here, we present a novel SINE-VNTR-Alu (SVA) insertion in exon 12 of MSH2 in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d29f3503f918e1486ee203c7639f133
https://doi.org/10.22541/au.160619405.59308303/v1
https://doi.org/10.22541/au.160619405.59308303/v1