Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David J. Faulkes"'
Autor:
Naushaad Suleman, Richard A. Knight, Anastasis Stephanou, David J. Faulkes, Paul A. Townsend, David S. Latchman, Christopher Carroll, Sean M. Davidson, James K.J. Diss
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 43:74-79
Heat shock proteins are known to be induced during and following different forms of cardiac stress. It has previously been shown that their expression is beneficial for the heart following trauma such as ischaemia-reperfusion (I/R) injury. Heat shock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43194fa4363f1f0919a3153c37530d7
https://doi.org/10.1016/j.biocel.2010.09.020
https://doi.org/10.1016/j.biocel.2010.09.020
Autor:
Mustafa B.A. Djamgoz, David S. Latchman, James K.J. Diss, Alpesh Patel, Christopher S. Foster, Vishwanie Budhram-Mahadeo, David J. Faulkes, Marjorie M. Walker
Publikováno v:
Prostate Cancer and Prostatic Diseases. 9:83-91
Neuroendocrine differentiation has been associated with prostate cancer (CaP). Brn-3a (short isoform) and Brn-3c, transcriptional controllers of neuronal differentiation, were readily detectable in human CaP both in vitro and in vivo. Brn-3a expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dbed79bade4e1fa5c0b2ca52cf9275
https://doi.org/10.1038/sj.pcan.4500837
https://doi.org/10.1038/sj.pcan.4500837
Publikováno v:
Molecular Brain Research. 141:10-18
Brn-3a is a transcription factor expressed in a subset of neurons of the peripheral nervous system. Its role encompasses the activation of genes involved in neuronal differentiation and survival. While a lot of data have been produced on Brn-3a targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66dedc61f8d98ad8f150020db0796f4b
https://doi.org/10.1016/j.molbrainres.2005.07.013
https://doi.org/10.1016/j.molbrainres.2005.07.013
Autor:
Vishwanie Budhram-Mahadeo, Laila Samady, Saleha R. Farooqui-Kabir, Jonathan H. Dennis, David J. Faulkes, David S. Latchman, Daniel Ndisang, Sonia A. Lee, Corrado D’Arrigo, Richard J. Heads, Chandrakant Patel
Publikováno v:
Cancer Research. 65:3072-3080
In breast cancer, overexpression of the small heat shock protein, HSP-27, is associated with increased anchorage-independent growth, increased invasiveness, and resistance to chemotherapeutic drugs and is associated with poor prognosis and reduced di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aefe8cedfc5da6ff742174ee9a54a63
https://doi.org/10.1158/0008-5472.can-04-2865
https://doi.org/10.1158/0008-5472.can-04-2865
Autor:
David J. Faulkes, David S. Latchman, Miratul M. K. Muqit, Luci P. MacCormac, Nicholas W. Wood
Publikováno v:
European Journal of Neuroscience. 20:2038-2048
Mutations in the parkin gene give rise to a familial form of Parkinson's disease, autosomal recessive juvenile Parkinsonism (AR-JP). Although the exact mechanisms are unclear, it is thought that these 'loss-of-function' mutations contribute to the pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::febf28e5824bd70b4b98086ffde814f4
https://doi.org/10.1111/j.1460-9568.2004.03659.x
https://doi.org/10.1111/j.1460-9568.2004.03659.x
Publikováno v:
NeuroReport. 15:1421-1425
The Brn-3a transcription factor is critical for the normal development of the nervous system, promoting both neuronal survival and neurite outgrowth. By manipulating the Brn-3a gene in intact mice, we show that these two functions are separately cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3245df99b5e4d7bfc6db2b3df021500
https://doi.org/10.1097/01.wnr.0000129371.81377.05
https://doi.org/10.1097/01.wnr.0000129371.81377.05
Publikováno v:
Biochemical and Biophysical Research Communications. 318:1045-1051
Brn-3a long and short isoforms are known to be encoded by two distinct mRNA transcripts derived from a single gene. Here we report that transcription of the two isoforms is differentially regulated. The short isoform has its own promoter, though many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f358b32b3842b805911b423757c0c2
https://doi.org/10.1016/j.bbrc.2004.04.134
https://doi.org/10.1016/j.bbrc.2004.04.134
Autor:
David J. Faulkes, Patricia Woo
Publikováno v:
Amyloid. 4:75-79
Restriction fragment length polymorphisms of the serum amyloid A, gene have been used to distinguish three alleles:-a1, a2 and β. The relative frequencies of these alleles in patients with systemic onset juvenile chronic arthritis (S-JCA) match thos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97f5b408ffddb51974aaa6f770e40a44
https://doi.org/10.3109/13506129708995274
https://doi.org/10.3109/13506129708995274
Publikováno v:
Amyloid. 1:255-262
The allelic variation of the serum amyloid A gene has been analyzed. We have identified five serum amyloid A1 alleles by genomic DNA sequence analysis that code for 3 protein variants. All three apoSAA proteins and both SAA2 proteins have been found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c49abb6a52f7e124701f2070b5d8ce8
https://doi.org/10.3109/13506129409146117
https://doi.org/10.3109/13506129409146117
Autor:
P Chen, Silvia S. Pierangeli, David J. Faulkes, David S. Latchman, N Lambrianides, David A. Isenberg, Nisha Pattni, Anisur Rahman, Ian Giles
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(3)
In the antiphospholipid syndrome (APS), antiphospholipid Abs (aPL) bind to anionic phospholipids (PL) and various associated proteins, especially β2-glycoprotein I (β2GPI) and prothrombin. In the present study, we show that altering specific Arg re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d156944f7886f6a21389e21be6fd61
https://pubmed.ncbi.nlm.nih.gov/16849482
https://pubmed.ncbi.nlm.nih.gov/16849482