Zobrazeno 1 - 10
of 27
pro vyhledávání: '"David J. Esdaile"'
Autor:
Ira Katz, Géraldine Farjot, Matthieu Chalopin, Kateryna Voronetska, Patricia Privat, Aude Milet, Guillaume Mougin, Mickaël Libardi, David J Esdaile
Publikováno v:
Laboratory Animals. 55:150-157
Several studies based on in vivo or in vitro models have found promising results for the noble gas argon in neuroprotection against ischaemic pathologies. The development of argon as a medicinal product includes the requirement for toxicity testing t
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis.
The safety of D-10-camphorsulfonic acid (CSA) was evaluated by genotoxicity testing and in a subchronic 90-day study in rats. Ames test and in vitro micronucleus test results, either in the absence or the presence of metabolic activation, were negati
Autor:
Judit Hargitai, Andrew Cockburn, Erzsébet Beres, Isabelle E.J.A. François, Madhu G. Soni, Raluca Kubaszky, Olivier Lescroart, Wim S. Veraverbeke, David J. Esdaile, Willem F. Broekaert
Publikováno v:
International Journal of Toxicology. 29:479-495
Wheat bran extract (WBE) is a food-grade preparation that is highly enriched in arabinoxylan-oligosaccharides. As part of the safety evaluation of WBE, its genotoxic potential was assessed in a bacterial reverse mutagenicity assay (Ames test) and a c
Autor:
Myriam Triest, David J Esdaile, Claude A. Piché, Morten Bendix Jensen, Magdolna Török-Bathó, C Nicholas Edwards, Dolorès Carballo, Frederick E. Reno
Publikováno v:
Cutaneous and ocular toxicology. 35(3)
The intranasal route is a promising route of administration for several emergency rescue drugs including naloxone and glucagon. Glucagon nasal powder (GNP) is a novel, needle-free delivery system for intranasal administration of glucagon for the trea
Autor:
Emanuela Corsini, M. Fartasch, Catherine Cohen, N. Fusenig, Roland Roguet, Maria Ponec, J.J.M. van de Sandt, Manfred Liebsch, D.J. Benford, David J. Esdaile, C. Barker, A. de Fraissinette
Publikováno v:
Alternatives to Laboratory Animals. 27:723-743
This is the report of the thirty-eighth of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). ECVAMs main goal, as defined in 1993 by its Scientific Advisory Committee, is to promote the scient
Publikováno v:
Xenobiotica. 29:655-691
1. An important feature of the work of many molecular biologists is identifying which genes are switched on and off in a cell under different environmental conditions or subsequent to xenobiotic challenge. Such information has many uses, including th
Autor:
O. de Silva, N. Dami, Penny Jones, L.H. Bruner, S. Freeman, P. Courtellemont, G. Thomas, David J. Esdaile, Jacqueline Southee, J. Dupuis, L. Declercq, R.W. Lewis, Y. Kasai, U. Kristen, W. Steiling, Hajime Kojima, A. Peterson, M. Bracher, K. Jung, F.W. Baker, G.J. Carr, D. Castelli, John W. Harbell, Uwe Pfannenbecker, M. Uttley, Richard H. Clothier, H. Itigaki, A.P. Walker, K. D. Marenus, H. Argembeaux, M. Chamberlain, M. Stern, C. Robles, O. Moreno, L.K. Earl, M. Tcheng, P. Brantom, E.S. Rasmussen, D.M. Bagley, W. J. W. Pape, M. Larnicol, D.P. Lovell
Publikováno v:
Toxicology in Vitro. 11:141-179
The principal goal of this study was to determine whether the results from a set of selected currently available alternative methods as used by cosmetics companies are valid for predicting the eye irritation potential of cosmetics formulations and in
Autor:
Philip A. Botham, Michael Balls, Bernhard Hildebrand, Maria Ponec, Richard W. Lewis, Virginia C. Gordon, Martin D. Barratt, Arthur P. Walker, Mark Chamberlain, Jean-François Régnier, John R. Gardner, David J. Esdaile, Pamela Logemann, W. Steiling, Manfred Liebsch, Rodger Curren, Rosemarie Osborne
Publikováno v:
Alternatives to Laboratory Animals. 23:219-242
Autor:
Y. Kasai, M. Bracher, David J. Esdaile, H. Argembeaux, Uwe Pfannenbecker, W. J. W. Pape, R.W. Lewis, S. Hagino
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 13(2)
The red blood cell test (RBC test) is part of the COLIPA Validation Project on Alternatives to Draize Eye Irritation. It shows good intra- and interlaboratory reproducibility (reliability) and represents one of the promising in vitro alternatives of
Autor:
Michael K. Baldwin, Suzanne L. Linnett, George C. Peristianis, Peter H. Berry, David J. Esdaile, Barry J. Simpson, John G. Martin, John D. Smith, Robert A.J. Priston
Publikováno v:
Toxicologic Pathology. 20:426-435
This investigation compared the effects of feeding rats diets containing food grade white oil processed by either conventional oleum treatment or the more modem method of catalytic hydrogenation. In two separate experiments, male or female Fischer-34