Zobrazeno 1 - 10
of 32
pro vyhledávání: '"David J. Elzi"'
Autor:
Fuchun Zhou, David J. Elzi, Panneerselvam Jayabal, Xiuye Ma, Yu-Chiao Chiu, Yidong Chen, Barron Blackman, Susan T. Weintraub, Peter J. Houghton, Yuzuru Shiio
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108332- (2020)
Summary: We report here that the autocrine signaling mediated by growth and differentiation factor 6 (GDF6), a member of the bone morphogenetic protein (BMP) family of cytokines, maintains Ewing sarcoma growth by preventing Src hyperactivation. Surpr
Externí odkaz:
https://doaj.org/article/da3653e6ea5645418c2ab8f61b70d9bb
Autor:
Panneerselvam Jayabal, Yuzuru Shiio, Peter J. Houghton, Fuchun Zhou, David J. Elzi, Barron Blackman, Yu-Chiao Chiu, Yi Chen, Xiuye Ma, Susan T. Weintraub
Publikováno v:
Cell Reports, Vol 33, Iss 5, Pp 108332-(2020)
Cell reports
Cell reports
SUMMARY We report here that the autocrine signaling mediated by growth and differentiation factor 6 (GDF6), a member of the bone morphogenetic protein (BMP) family of cytokines, maintains Ewing sarcoma growth by preventing Src hyperactivation. Surpri
Autor:
Peter Zannes Fatland, Moises Iza, Vivienne I. Rebel, Jamila R. Sanchez, Alexander Pertsemlidis, Shweta Mogare, William E. Bauta, Trisha Das, David J. Elzi
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(3)
Porphyrins are used for cancer diagnostic and therapeutic applications, but the mechanism of how porphyrins accumulate in cancer cells remains elusive. Knowledge of how porphyrins enter cancer cells can aid the development of more accurate cancer dia
Autor:
Shao-Chiang Lai, Vivienne I. Rebel, David J. Elzi, Trisha Das, William E. Bauta, Shweta Mogare
Publikováno v:
Cancer Research. 81:1223-1223
Designing effective therapies with selective toxicity in cancer cells is a priority of cancer research. Porphyrins are known to selectively accumulate in cancerous tissue, a feature that has been exploited in cancer diagnostics and therapeutics. The
Autor:
David J. Elzi, Samina Y. Khan, Anirban Banerjee, Kelly M. England, Susan Kuldanek, Christopher C. Silliman, F. Bernadette West, Jason Bjornsen, Nathan J. D. McLaughlin, Marguerite R. Kelher
Publikováno v:
Transfusion. 57:2690-2700
BACKGROUND Although transfusion is a lifesaving intervention, it may be associated with significant morbidity in injured patients. We hypothesize that stored red blood cells (RBCs) induce proinflammatory activation of human pulmonary microvascular en
Autor:
Barron Blackman, Gail E. Tomlinson, Yuzuru Shiio, David J. Elzi, Susan T. Weintraub, Dolores Lopez-Terrada, Yi Chen, Meihua Song
Publikováno v:
Genes & Cancer
Hepatoblastoma is the most common liver cancer in children, accounting for over 65% of all childhood liver malignancies. Hepatoblastoma is distinct from adult liver cancer in that it is not associated with hepatitis virus infection, cirrhosis, or oth
Publikováno v:
Experimental Gerontology. 73:1-4
Cellular senescence has been proposed to play critical roles in tumor suppression and organismal aging, but the molecular mechanism of senescence remains incompletely understood. Here we report that a putative lysosomal carbohydrate efflux transporte
Publikováno v:
Genes & Cancer
Ewing sarcoma is a cancer of bone and soft tissue in children that is characterized by a chromosomal translocation involving EWS and an Ets family transcription factor, most commonly FLI-1. The EWS-FLI-1 fusion oncogene is widely believed to play a c
Autor:
Christopher C, Silliman, Marguerite R, Kelher, Samina Y, Khan, F Bernadette, West, Nathan J D, McLaughlin, David J, Elzi, Kelly, England, Jason, Bjornsen, Susan A, Kuldanek, Anirban, Banerjee
Publikováno v:
Transfusion. 57(11)
Although transfusion is a lifesaving intervention, it may be associated with significant morbidity in injured patients. We hypothesize that stored red blood cells (RBCs) induce proinflammatory activation of human pulmonary microvascular endothelial c
Autor:
Christopher C. Silliman, Xianzhong Meng, Nathan J. D. McLaughlin, Marguerite R. Kelher, Anirban Banerjee, Sanchayita Mitra, Fabia Gamboni, Samina Y. Khan, David J. Elzi
Lysophosphatidylcholines (lysoPCs) are effective polymorphonuclear neutrophil (PMN) priming agents implicated in transfusion-related acute lung injury (TRALI). LysoPCs cause ligation of the G2A receptor, cytosolic Ca2+ flux, and activation of Hck. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726f8e1e665ae4479f2808bb779d2c42
https://europepmc.org/articles/PMC5166440/
https://europepmc.org/articles/PMC5166440/