Zobrazeno 1 - 10
of 47
pro vyhledávání: '"David J. Culp"'
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Saliva protects dental surfaces against cavities (i. e., dental caries), a highly prevalent infectious disease frequently associated with acidogenic Streptococcus mutans. Substantial in vitro evidence supports amylase, a major constituent of saliva,
Externí odkaz:
https://doaj.org/article/4049417aeff8451a8c944320c19cc8b0
Publikováno v:
mSphere, Vol 3, Iss 1 (2018)
ABSTRACT Transposon mutagenesis coupled with next-generation DNA sequencing (Tn-seq) is a powerful tool for discovering regions of the genome that are required for the survival of bacteria in different environments. We adapted this technique to the d
Externí odkaz:
https://doaj.org/article/f6bb3f099fde41e29ed284e210c02913
Autor:
David J. Culp, William Hull, Alexander C. Schultz, Ashley S. Bryant, Claudia A. Lizarraga, Madeline R. Dupuis, Brinta Chakraborty, Kyulim Lee, Robert A. Burne
Publikováno v:
Journal of Applied Microbiology. 132:3853-3869
Aims We evaluated two species of human oral commensal streptococci in protection against dental caries induced by Streptococcus mutans. Methods and Results Candidate probiotics, Streptococcus sp. A12, Streptococcus sanguinis BCC23 and an arginine dei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c0b922f99e0854f9ff0ffce7fb9556
https://doi.org/10.1111/jam.15516
https://doi.org/10.1111/jam.15516
Autor:
Tanya Puccio, Seon‐Sook An, Alexander C. Schultz, Claudia A. Lizarraga, Ashley S. Bryant, David J. Culp, Robert A. Burne, Todd Kitten
Publikováno v:
Molecular Microbiology. 117:375-393
Streptococcus sanguinis is an oral commensal and an etiological agent of infective endocarditis. Previous studies have identified the SsaACB manganese transporter as essential for endocarditis virulence; however, the significance of SsaACB in the ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963939577b7c89b6f6f37a191fce25b3
https://doi.org/10.1111/mmi.14854
https://doi.org/10.1111/mmi.14854
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 472:385-403
Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via increased intracellular free calcium ([Ca2+]i) and activation of conventional protein kinase C iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e9027ca002b35194bfe90323addb67
https://doi.org/10.1007/s00424-020-02348-7
https://doi.org/10.1007/s00424-020-02348-7
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Saliva protects dental surfaces against cavities (i. e., dental caries), a highly prevalent infectious disease frequently associated with acidogenic Streptococcus mutans. Substantial in vitro evidence supports amylase, a major constituent of saliva,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06132320682b96800551d1f4b458c49c
https://doi.org/10.3389/fphys.2021.699104
https://doi.org/10.3389/fphys.2021.699104
Autor:
Seon-Sook An, Robert A. Burne, Todd Kitten, Ashley S. Bryant, Tanya Puccio, David J. Culp, Alexander C. Schultz, Claudia A. Lizarraga
SummaryStreptococcus sanguinis is an oral commensal and an etiological agent of infective endocarditis. Previous studies have identified the SsaACB manganese transporter as essential for endocarditis virulence; however, the significance of SsaACB in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e49ad1c6b948155e456807b0877056e0
https://doi.org/10.1101/2021.05.28.446192
https://doi.org/10.1101/2021.05.28.446192
Autor:
Timmy Chen, William Hull, Deneen S. Wang, Mary Killeen, Kyulim Lee, Matthew J. Bremgartner, Kacey N. Christian, Robert A. Burne, Madeline R. Dupuis, Verisha Afzal, Brinta Chakraborty, Todd A. Atherly, David J. Culp, Alexander C. Schultz
Publikováno v:
Applied and Environmental Microbiology
Our results demonstrate that in vivo testing of potential oral probiotics can be accomplished and can yield information to facilitate the ultimate design and optimization of novel anticaries probiotics. We show that human oral commensals associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce0caf457fdec6a0e3081df928636dc
http://europepmc.org/articles/PMC7851695
http://europepmc.org/articles/PMC7851695
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Lack of LrgAB renders cariogenic Streptococcus mutans more sensitive to oxidative stress, as well as limits the capacity of this organism to re-uptake pyruvate upon starvation. This study was aimed at investigating the ecological and metabolic contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f6db60793c8c7891db23d7eb81d0f
https://doi.org/10.3389/fmicb.2020.02119
https://doi.org/10.3389/fmicb.2020.02119
Publikováno v:
Pflugers Arch
Mucin secretion by salivary mucous glands is mediated predominantly by parasympathetic acetylcholine activation of cholinergic muscarinic receptors via increased intracellular free calcium ([Ca(2+)](i)) and activation of conventional protein kinase C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3ad3ccd549cb5f914871ac7e153b551
https://pubmed.ncbi.nlm.nih.gov/31932898
https://pubmed.ncbi.nlm.nih.gov/31932898