Zobrazeno 1 - 10
of 233
pro vyhledávání: '"David J. Clarke"'
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Intervention fidelity in health services research has been poor with a reported lack of understanding about what constitutes pragmatic adaptation of interventions and what constitutes failure to maintain intervention fidelity. How
Externí odkaz:
https://doaj.org/article/a952f3af407841f29dfe6014831b5a94
Autor:
Clodagh M. Carr, Frederike Göttsch, Bruno Francesco Rodrigues deOliveira, Pedro A. Sánchez Murcia, Stephen A. Jackson, Ren Wei, David J. Clarke, Uwe T. Bornscheuer, Alan D. W. Dobson
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 6, Pp n/a-n/a (2024)
Abstract Carboxylic ester hydrolases with the capacity to degrade polyesters are currently highly sought after for their potential use in the biological degradation of PET and other chemically synthesized polymers. Here, we describe MarCE, a carboxyl
Externí odkaz:
https://doaj.org/article/f849cd1fcf554dbb9bf8099421c703b3
A mechanistic evaluation of human beta defensin 2 mediated protection of human skin barrier in vitro
Autor:
Jennifer R. Shelley, Brian J. McHugh, Jimi Wills, Julia R. Dorin, Richard Weller, David J. Clarke, Donald J. Davidson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The human skin barrier, a biological imperative, is impaired in inflammatory skin diseases such as atopic dermatitis (AD). Staphylococcus aureus is associated with AD lesions and contributes to pathological inflammation and further barrier i
Externí odkaz:
https://doaj.org/article/611c43cc68e3410ea8aa84140ed00cd1
Autor:
Shan Wang, Sixing Lin, Qing Fang, Roland Gyampoh, Zhou Lu, Yingli Gao, David J. Clarke, Kewen Wu, Laurent Trembleau, Yi Yu, Kwaku Kyeremeh, Bruce F. Milne, Jioji Tabudravu, Hai Deng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The chemical diversity of peptides from ribosomal origin is a growing field of research. Here, the authors report the discovery, genomic and biosynthetic investigations of kintamdin, a ribosomally synthesized and post-translationally modified peptide
Externí odkaz:
https://doaj.org/article/8b57a4ca631948b589837ff094434bec
Autor:
Elsa Zacco, Owen Kantelberg, Edoardo Milanetti, Alexandros Armaos, Francesco Paolo Panei, Jenna Gregory, Kiani Jeacock, David J. Clarke, Siddharthan Chandran, Giancarlo Ruocco, Stefano Gustincich, Mathew H. Horrocks, Annalisa Pastore, Gian Gaetano Tartaglia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here, the authors generated an artificial RNA molecule, or aptamer, specific for the Amyotrophic Lateral Sclerosis protein TDP-43. By interacting avidly with its target, the aptamer can be exploited to track TDP-43 phase transition in vitro and in ce
Externí odkaz:
https://doaj.org/article/313504fc94a146ba963e22a3b9d3a822
Autor:
Clodagh M. Carr, Malene B. Keller, Bijoya Paul, Sune W. Schubert, Kristine S. R. Clausen, Kenneth Jensen, David J. Clarke, Peter Westh, Alan D. W. Dobson
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The successful enzymatic degradation of polyester substrates has fueled worldwide investigation into the treatment of plastic waste using bio-based processes. Within this realm, marine-associated microorganisms have emerged as a promising source of p
Externí odkaz:
https://doaj.org/article/087d005c997a4245819954d6b162183e
Autor:
Clodagh M. Carr, Bruno Francesco Rodrigues de Oliveira, Stephen A. Jackson, Marinella Silva Laport, David J. Clarke, Alan D. W. Dobson
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Many marine bacteria produce extracellular enzymes that degrade complex molecules to facilitate their growth in environmental conditions that are often harsh and low in nutrients. Marine bacteria, including those inhabiting sea sponges, have previous
Externí odkaz:
https://doaj.org/article/20c8de3b0de24e0ba1b922c509e2bff4
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/de7f240c80c54bfc8a41f8a4412739be
Publikováno v:
Metabolites, Vol 13, Iss 3, p 360 (2023)
There has been increasing interest in bacterial lipids in recent years due, in part, to their emerging role as molecular signalling molecules. Bacteroides thetaiotaomicron is an important member of the mammalian gut microbiota that has been shown to
Externí odkaz:
https://doaj.org/article/2dd7c7b1b3c944eb95cac180ed728a55
Autor:
Andreas Tsiamis, Anthony Buchoux, Stephen T. Mahon, Anthony J. Walton, Stewart Smith, David J. Clarke, Adam A. Stokes
Publikováno v:
Micromachines, Vol 14, Iss 3, p 537 (2023)
The lab-on-a-chip concept, enabled by microfluidic technology, promises the integration of multiple discrete laboratory techniques into a miniaturised system. Research into microfluidics has generally focused on the development of individual elements
Externí odkaz:
https://doaj.org/article/a72c7c4011044c4d8596c3971b18e8e1