Zobrazeno 1 - 10
of 52
pro vyhledávání: '"David J. Brunswick"'
Publikováno v:
Journal of Psychiatric Research. 38:259-265
The objective of this paper is to evaluate the efficacy of gepirone immediate-release (gepirone-IR) for relapse prevention in outpatients with MDD who had responded to initial gepirone-IR therapy. Patients with MDD and a HAM-D(25) scoreor = 20 were t
Autor:
Jay D. Amsterdam, David J. Brunswick
Publikováno v:
Bipolar Disorders. 5:388-395
Objectives: Bipolar type II (BP II) disorder is thought to be distinct from BP I disorder on genetic and biological grounds, and it is not merely a milder form of the illness. It affects 1.5–2.5% of the US adult population, and is characterized by
Publikováno v:
American Journal of Psychiatry. 160:1836-1841
Studies of laboratory animals have shown that administration of antidepressants of all pharmacological classes produces changes in dopamine transporter binding affinity. These observations suggest that dopamine transporter function may play a critica
Publikováno v:
Psychiatric Annals. 32:452-462
Autor:
Jay D. Amsterdam, Jerrold F. Rosenbaum, Jan Fawcett, Charles M. Beasley, Frederic M. Quitkin, David J. Brunswick, Frederick W. Reimherr
Publikováno v:
Journal of Affective Disorders. 68:243-249
Background: Virtually no attention has been given to the relationship between antidepressant plasma drug concentrations and relapse-prevention during maintenance therapy. The purpose of this study was to investigate the relationship between steady-st
Publikováno v:
Current Opinion in Psychiatry. 13:93-98
Autor:
Jay D. Amsterdam, Fredrick W. Reimherr, Quitkin Fm, Jan Fawcett, David J. Brunswick, Charles M. Beasley, Jerrold F. Rosenbaum
Publikováno v:
Journal of Clinical Psychopharmacology. 21:616-618
Publikováno v:
Synapse. 11:287-293
The neurotoxicity of methamphetamine to monoaminergic neurons was examined. Neurotoxicity was assessed by quantitative autoradiography using radioligands specific for binding to norepinephrine, dopamine, and serotonin uptake sites. High-dose administ
Publikováno v:
Life Sciences. 47:841-848
N-Substituted derivatives of 4-piperidinyl benzilate were synthesized and their affinities for central muscarinic cholinergic receptors determined using an in vitro radioligand binding assay. 4-Piperidinyl benzilate exhibited a Ki value of 2.0 nM. N-
Publikováno v:
Bipolar disorders. 6(1)
Objectives: Current guidelines for the initial treatment of bipolar type II (BP II) major depressive episode (MDE) recommend using either a mood stabilizer alone or a combination of a mood stabilizer plus a selective serotonin re-uptake inhibitor (SS