Zobrazeno 1 - 10
of 11
pro vyhledávání: '"David J. Babinski"'
Publikováno v:
Journal of the American Chemical Society. 137:3775-3778
We report the first example of ipso-borylation for the modular 1,2-bisfunctionalization of aryl iodides via C-H functionalization. The carbon-boron bond is used as a lynchpin to access ipso carbon-carbon, carbon-nitrogen, carbon-oxygen, and carbon-ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8489ac27c9fc1a644089d1688abf6b8c
https://doi.org/10.1021/jacs.5b01082
https://doi.org/10.1021/jacs.5b01082
Publikováno v:
ChemInform. 46
A novel and general method for the construction of a variety of disubstituted anilines is reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d2b9b8ea97ebd115424aa3a9f08c797
https://doi.org/10.1002/chin.201531076
https://doi.org/10.1002/chin.201531076
Publikováno v:
Organometallics. 24:475-478
Palladium-catalyzed reactions of unsaturated organozincs with aryl or alkenyl iodides can exhibit turnover numbers (TONs) over 105 (>70% product yields). Under the conditions employed, Zn, B, and In appear to be the three most favorable metals, follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb5ff25fb72bf0afa1007c097868d3c
https://doi.org/10.1021/om049106j
https://doi.org/10.1021/om049106j
Autor:
Evelyn M. Jackson, David J. Babinski, April L. Risinger, Jiangnan Peng, Gregory L. Helms, Susan L. Mooberry, Doug E. Frantz
Publikováno v:
Journal of Natural Products. 73:1590-1592
A new benzoquinone-type retro-dihydrochalcone, named evelynin, was isolated from the roots and rhizomes of Tacca chantrieri. The structure was elucidated based on the analysis of spectroscopic data and confirmed by a simple one-step total synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe369188fbddb84ed3e275ad484e6d10
https://doi.org/10.1021/np100350s
https://doi.org/10.1021/np100350s
Autor:
Junjie Xu, Elisabeth D. Martinez, Amy M. Quinn, Richard K. Bruick, Anne M. Best, Lei Wang, Doug E. Frantz, Julio C. Ruiz, Jianjun Chang, David J. Babinski, Anton Simeonov, Subodh Kumar, Rolf A. Brekken, Michael T. Dellinger, Samuel Peña-Llopis, Diana Varghese, Johnny Easmon
Publikováno v:
Nature Communications. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb33ea989bf857dda2a9b554bc722c7f
https://doi.org/10.1038/ncomms3639
https://doi.org/10.1038/ncomms3639
Autor:
Junjie Xu, Elisabeth D. Martinez, Samuel Peña-Llopis, Lei Wang, Anne M. Best, Doug E. Frantz, Jianjun Chang, Subodh Kumar, Diana Varghese, Johnny Easmon, Richard K. Bruick, Rolf A. Brekken, Michael T. Dellinger, David J. Babinski, Julio C. Ruiz, Amy M. Quinn, Anton Simeonov
Publikováno v:
Nature communications
The pharmacological inhibition of general transcriptional regulators has the potential to block growth through targeting multiple tumorigenic signalling pathways simultaneously. Here, using an innovative cell-based screen, we identify a structurally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ce8765def6ff70d8dcda335b518bef
https://www.ncbi.nlm.nih.gov/pubmed/23792809
https://www.ncbi.nlm.nih.gov/pubmed/23792809
Autor:
David J. Babinski, Doug E. Frantz, Xiaoguang Bao, David A. Hrovat, Bo Chen, Weston Thatcher Borden, Marie El Arba
Publikováno v:
Journal of the American Chemical Society. 134(39)
We report herein experimental and theoretical evidence for an aromatic Cope rearrangement. Along with several successful examples, our data include the first isolation and full characterization of the putative intermediate that is formed immediately
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dc4f6bfca10ce075bc5b5b83c052f9
https://pubmed.ncbi.nlm.nih.gov/22963196
https://pubmed.ncbi.nlm.nih.gov/22963196
Publikováno v:
The Journal of organic chemistry. 76(15)
The synthesis of 3,4,5-trisubstituted pyrazoles via a tandem catalytic cross-coupling/electrocyclization of enol triflates and diazoacetates is presented. The initial scope of this methodology is demonstrated on a range of differentially substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21e23f4b957a14505fded4b971fad25
https://pubmed.ncbi.nlm.nih.gov/21682322
https://pubmed.ncbi.nlm.nih.gov/21682322
Publikováno v:
ChemInform. 39
A highly stereoselective method for preparing (Z)- and (E)-enol triflates derived from substituted acetoacetate derivatives is described. The salient feature of this methodology is the use of Schotten−Baumann-type conditions to control enolate geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d508781f7cb8cb3d779ee47d5795b09
https://doi.org/10.1002/chin.200844053
https://doi.org/10.1002/chin.200844053
Publikováno v:
Organic letters. 10(13)
A highly stereoselective method for preparing ( Z)- and ( E)-enol triflates derived from substituted acetoacetate derivatives is described. The salient feature of this methodology is the use of Schotten-Baumann-type conditions to control enolate geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002d76efbd80fba39bc4f0f17861ba84
https://pubmed.ncbi.nlm.nih.gov/18540630
https://pubmed.ncbi.nlm.nih.gov/18540630