Zobrazeno 1 - 10
of 716
pro vyhledávání: '"David J. Mooney"'
Autor:
Mor Grinstein, Stephanie L. Tsai, Daniel Montoro, Benjamin R. Freedman, Heather L. Dingwall, Steffany Villaseñor, Ken Zou, Moshe Sade-Feldman, Miho J. Tanaka, David J. Mooney, Terence D. Capellini, Jayaraj Rajagopal, Jenna L. Galloway
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-19 (2024)
Abstract A tendon’s ordered extracellular matrix (ECM) is essential for transmitting force but is also highly prone to injury. How tendon cells embedded within and surrounding this dense ECM orchestrate healing is not well understood. Here, we iden
Externí odkaz:
https://doaj.org/article/c834ecd0f24940eb95c1c70b6436a560
Autor:
Kwasi Adu-Berchie, Joshua M. Brockman, Yutong Liu, Tania W. To, David K. Y. Zhang, Alexander J. Najibi, Yoav Binenbaum, Alexander Stafford, Nikolaos Dimitrakakis, Miguel C. Sobral, Maxence O. Dellacherie, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a h
Externí odkaz:
https://doaj.org/article/c82858dc6c3249e0bed06dcad9fd4919
Autor:
Nuria Lafuente-Gómez, Irene de Lázaro, Mónica Dhanjani, David García-Soriano, Miguel C. Sobral, Gorka Salas, David J. Mooney, Álvaro Somoza
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100817- (2023)
Immunotherapy has emerged as a promising strategy to eradicate cancer cells. Particularly, the development of cancer vaccines to induce a potent and sustained antigen-specific T cell response has become a center of attention. Herein, we describe a no
Externí odkaz:
https://doaj.org/article/58b1cab7cdf242c4bff8ae3f5be0c307
Autor:
David K. Y. Zhang, Kwasi Adu-Berchie, Siddharth Iyer, Yutong Liu, Nicoletta Cieri, Joshua M. Brockman, Donna Neuberg, Catherine J. Wu, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
‘Manufacturing CAR-T cells is a streamlined and highly regulated procedure involving T-cell-expansion and activation on a standardised platform. Here, the authors show that a personalized approach, taking the phenotypic attributes of individual pat
Externí odkaz:
https://doaj.org/article/f7959b99a7e04e99918762da2d538fbb
Autor:
David T. Wu, Mani Diba, Stephanie Yang, Benjamin R. Freedman, Alberto Elosegui‐Artola, David J. Mooney
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Multicellular spheroids made of stem cells can act as building blocks that fuse to capture complex aspects of native in vivo environments, but the effect of hydrogel viscoelasticity on cell migration from spheroids and their fusion remains l
Externí odkaz:
https://doaj.org/article/86c142d3d71a489492cc0e9b3d292f96
Autor:
Matthew D. Kerr, David A. McBride, Wade T. Johnson, Arun K. Chumber, Alexander J. Najibi, Bo Ri Seo, Alexander G. Stafford, David T. Scadden, David J. Mooney, Nisarg J. Shah
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Neutrophils are essential effector cells for mediating rapid host defense and their insufficiency arising from therapy‐induced side‐effects, termed neutropenia, can lead to immunodeficiency‐associated complications. In autologous hemat
Externí odkaz:
https://doaj.org/article/e291967d88574f02ad306dcef7787a12
Autor:
Hua Wang, Alexander J. Najibi, Miguel C. Sobral, Bo Ri Seo, Jun Yong Lee, David Wu, Aileen Weiwei Li, Catia S. Verbeke, David J. Mooney
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The immunosuppressive tumour microenvironment impairs immunotherapy in poorly immunogenic cancer. Here, the authors load an alginate gel with GM-CSF, CpG oligonucleotides and doxorubicin-iRGD to promote immunogenic death of tumour cells and improve i
Externí odkaz:
https://doaj.org/article/2af10e759cc3482da0ca26d55a1844d7
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010240 (2022)
Staphylococcus aureus bacteremia (SAB) remains a clinically challenging infection despite extensive investigation. Repurposing medications approved for other indications is appealing as clinical safety profiles have already been established. Ticagrel
Externí odkaz:
https://doaj.org/article/59eac2d7c78f4f67b1ba271c52323c5e
Publikováno v:
Nature Reviews Bioengineering. 1:271-285
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b65151dff7a2925e22bfe0e4f0172f50
https://doi.org/10.1038/s44222-023-00031-x
https://doi.org/10.1038/s44222-023-00031-x
Publikováno v:
Chemical Reviews, 123, 2, pp. 834-873
Chemical Reviews, 123, 834-873
Chemical Reviews, 123, 834-873
Contains fulltext : 291335.pdf (Publisher’s version ) (Open Access) Biomaterials with the ability to self-heal and recover their structural integrity offer many advantages for applications in biomedicine. The past decade has witnessed the rapid eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8464d3e6e63c2e5a44b1125bea08b25
https://hdl.handle.net/2066/291335
https://hdl.handle.net/2066/291335