Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David J Wooten"'
Autor:
David J Wooten, Sarah M Groves, Darren R Tyson, Qi Liu, Jing S Lim, Réka Albert, Carlos F Lopez, Julien Sage, Vito Quaranta
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 10, p e1007343 (2019)
Adopting a systems approach, we devise a general workflow to define actionable subtypes in human cancers. Applied to small cell lung cancer (SCLC), the workflow identifies four subtypes based on global gene expression patterns and ontologies. Three c
Externí odkaz:
https://doaj.org/article/fbce162d02af49a5a07ed1284de14ab8
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 3, p 193 (2021)
FLT3-mutant acute myeloid leukemia (AML) is an aggressive form of leukemia with poor prognosis. Treatment with FLT3 inhibitors frequently produces a clinical response, but the disease nevertheless often recurs. Recent studies have revealed system-wid
Externí odkaz:
https://doaj.org/article/e45566c08bcf4609825b1eb57065f3ce
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Drug combination discovery depends on reliable synergy metrics but no consensus exists on the correct synergy criterion to characterize combined interactions. The fragmented state of the field confounds analysis, impedes reproducibility, and delays c
Publikováno v:
Trends Pharmacol Sci
Even as the clinical impact of drug combinations continues to accelerate, no consensus on how to quantify drug synergy has emerged. Rather, surveying the landscape of drug synergy reveals the persistence of historical fissures regarding the appropria
Autor:
Peter A. Dowben, Yaroslav B. Losovyj, Jie Xiao, James Petrosky, Ihor Ketsman, David. J. Wooten, John McClory, Volodymyr.T. Adamiv, Yaroslav.V. Burak
Publikováno v:
Materials, Vol 3, Iss 9, Pp 4550-4579 (2010)
We review the pyroelectric properties and electronic structure of Li2B4O7(110) and Li2B4O7(100) surfaces. There is evidence for a pyroelectric current along the [110] direction of stoichiometric Li2B4O7 so that the pyroelectric coefficient is nonzero
Externí odkaz:
https://doaj.org/article/c78e04c6a1194f0b950696afab36f084
Autor:
Rebecca A. Ihrie, Vito Quaranta, L. Taylor Davis, David J. Wooten, Akshitkumar M. Mistry, Bret C. Mobley
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Whether patients with glioblastoma that contacts the ventricular-subventricular zone stem cell niche (VSVZ + GBM) have a distinct survival profile from VSVZ − GBM patients independent of other known predictors or molecular profiles is unclear. Usin
Autor:
Reinhard Laubenbacher, Jorge Gómez Tejeda Zañudo, David Murrugarra, Anna Dongari-Bagtzoglou, David J. Wooten, Clarissa J. Nobile, Austin M. Perry, Réka Albert
Publikováno v:
PLoS computational biology, vol 17, iss 3
PLoS Computational Biology, Vol 17, Iss 3, p e1008690 (2021)
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 3, p e1008690 (2021)
PLoS Computational Biology
Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic plasticity between two morphological phenotypes, yeast and hyphae, is a key mechanism by which C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f4b85609974b22544099b48241064c
https://escholarship.org/uc/item/7rh0779n
https://escholarship.org/uc/item/7rh0779n
Publikováno v:
Journal of Personalized Medicine
Volume 11
Issue 3
Journal of Personalized Medicine, Vol 11, Iss 193, p 193 (2021)
Volume 11
Issue 3
Journal of Personalized Medicine, Vol 11, Iss 193, p 193 (2021)
FLT3-mutant acute myeloid leukemia (AML) is an aggressive form of leukemia with poor prognosis. Treatment with FLT3 inhibitors frequently produces a clinical response, but the disease nevertheless often recurs. Recent studies have revealed system-wid
Autor:
Clarissa J. Nobile, Anna Dongari-Bagtzoglou, David Murrugarra, David J. Wooten, Réka Albert, Austin M. Perry, Jorge Gómez Tejeda Zañudo, Reinhard Laubenbacher
Candida albicans, an opportunistic fungal pathogen, is a significant cause of human infections, particularly in immunocompromised individuals. Phenotypic plasticity between two morphological phenotypes, yeast and hyphae, is a key mechanism by whichC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d130d5827293bf3a50d3fbc458eb370b
https://doi.org/10.1101/2021.01.20.427417
https://doi.org/10.1101/2021.01.20.427417