Zobrazeno 1 - 10
of 107
pro vyhledávání: '"David J Williamson"'
Autor:
Tim D Fryer, Sohail Ejaz, Ulf Jensen-Kondering, David J Williamson, Sergey Sitnikov, Stephen J Sawiak, Franklin I Aigbirhio, Young T Hong, Jean-Claude Baron
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187087 (2017)
PURPOSE:Mapping brain hypoxia is a major goal for stroke diagnosis, pathophysiology and treatment monitoring. 18F-fluoro-misonidazole (FMISO) positron emission tomography (PET) is the gold standard hypoxia imaging method. Normobaric hyperoxia (NBO) i
Externí odkaz:
https://doaj.org/article/31b890ecea78418fb3b8cdbfaa56a525
Autor:
Sohail eEjaz, David J Williamson, Ulf eJensen-Kondering, Tahir eAhmed, Stephen John Sawiak, Jean-Claude eBaron
Publikováno v:
Frontiers in Neurology, Vol 6 (2015)
Introduction and Objectives: Selective neuronal loss (SNL) in the reperfused penumbra may impact clinical recovery and is thus important to investigate. Brief proximal middle cerebral artery occlusion (MCAo) results in predominantly striatal SNL, yet
Externí odkaz:
https://doaj.org/article/38896854b6f54e8f994115622a18e7d0
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
Engagement of the T cell antigen receptor (TCR) triggers signalling pathways that lead to T cell selection, differentiation and clonal expansion. Superimposed onto the biochemical network is a spatial organization that describes individual receptor m
Externí odkaz:
https://doaj.org/article/17d5d2cff65a4ba7bdede513beb019d5
Autor:
Tobias Starling, Irene Carlon-Andres, Maro Iliopoulou, Benedikt Kraemer, Maria Loidolt-Krueger, David J. Williamson, Sergi Padilla-Parra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Simultaneous imaging of nine fluorescent proteins is demonstrated in a single acquisition using fluorescence lifetime imaging microscopy combined with pulsed interleaved excitation of three laser lines. Multicolor imaging employing genetical
Externí odkaz:
https://doaj.org/article/0da9e271dc724c688bf99fdcec5810b5
Autor:
Daniel J. Nieves, Jeremy A. Pike, Florian Levet, David J. Williamson, Mohammed Baragilly, Sandra Oloketuyi, Ario de Marco, Juliette Griffié, Daniel Sage, Edward A. K. Cohen, Jean-Baptiste Sibarita, Mike Heilemann, Dylan M. Owen
Publikováno v:
Nature Methods. 20:259-267
This analysis compares the performance of seven algorithms for cluster analysis of single-molecule localization microscopy data. The results provide a framework for comparing these types of methods and point users to the best tools.
Single-molec
Single-molec
Autor:
Nisha K. Ramakrishnan, Helen M. Betts, Selena Milicevic Sephton, Xiaoyun Zhou, David J. Williamson, Stephen Sawiak, Franklin I. Aigbirhio
Publikováno v:
Nuclear Medicine and Biology. :71-77
Autor:
Louis G. Jensen, Tjun Yee Hoh, David J. Williamson, Juliette Griffié, Daniel Sage, Patrick Rubin-Delanchy, Dylan M. Owen
Publikováno v:
Jensen, L G, Hoh, T Y, Williamson, D J, Griffié, J, Sage, D, Rubin-Delanchy, P & Owen, D M 2022, ' Correction of multiple-blinking artifacts in photoactivated localization microscopy ', Nature Methods, vol. 19, no. 5, pp. 594-602 . https://doi.org/10.1038/s41592-022-01463-w
Photoactivated localization microscopy (PALM) produces an array of localization coordinates by means of photoactivatable fluorescent proteins. However, observations are subject to fluorophore multiple blinking and each protein is included in the data
Autor:
David J, Williamson, Jagadish P, Gogate, Jennifer K, Kern Sliwa, Lewis S, Manera, Sheldon H, Preskorn, Andrew, Winokur, H Lynn, Starr, Ella J, Daly
Publikováno v:
The Journal of Clinical Psychiatry. 83
Single-molecule localisation microscopy produces data in the form of point-clouds. Here, we present a tool for assessing the similarity of two such point-clouds, which, unlike measures such as co-localisation, is insensitive to differences that are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a30fce531a0f07ba3bc1da66eaf93f1
https://doi.org/10.1101/2022.09.12.507560
https://doi.org/10.1101/2022.09.12.507560
Autor:
Manish K. Jha, David J. Williamson, Ghazal Magharehabed, Ibrahim Turkoz, Ella J. Daly, Madhukar H. Trivedi
Publikováno v:
Journal of affective disorders. 321
To evaluate the impact of baseline irritability on clinical outcomes in adults with treatment-resistant depression (TRD) treated with fixed or flexible doses of esketamine nasal spray plus a newly initiated oral antidepressant (ESK+AD) and to explore