Zobrazeno 1 - 10
of 26
pro vyhledávání: '"David J Wiley"'
Autor:
Illyce Nuñez, Marbelys Rodriguez Pino, David J Wiley, Maitreyi E Das, Chuan Chen, Tetsuya Goshima, Kazunori Kume, Dai Hirata, Takashi Toda, Fulvia Verde
Publikováno v:
eLife, Vol 5 (2016)
RNA-binding proteins contribute to the formation of ribonucleoprotein (RNP) granules by phase transition, but regulatory mechanisms are not fully understood. Conserved fission yeast NDR (Nuclear Dbf2-Related) kinase Orb6 governs cell morphogenesis in
Externí odkaz:
https://doaj.org/article/7e5b63e5d331457a8b9899440ab6ec8f
Autor:
Peter Buchwald, Fulvia Verde, David J. Wiley, Marbelys Rodriguez Pino, Dimitrios Vavylonis, Illyce Nuñez, Maitreyi Das, Gennaro D'Urso, Chuan Chen
The highly conserved small GTPase Cdc42 regulates polarized cell growth and morphogenesis from yeast to humans. We previously reported that Cdc42 activation exhibits oscillatory dynamics inSchizosaccharomyces pombecells. Mathematical modeling suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908997f9bb23b328041eee103bbed8e9
https://doi.org/10.1101/2020.06.16.151308
https://doi.org/10.1101/2020.06.16.151308
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology, Vol 11 (2020)
Arginyltransferase1 (ATE1) is a conserved enzyme in eukaryotes mediating posttranslational arginylation, the addition of an extra arginine to an existing protein. In mammals, the dysregulations of the ATE1 gene (ate1) is shown to be involved in cardi
Autor:
Marbelys Rodriguez Pino, David J. Wiley, Dimitrios Vavylonis, Chuan Chen, Peter Buchwald, Illyce Nuñez, Maitreyi Das, Gennaro D'Urso, Fulvia Verde
Publikováno v:
Molecular Biology of the Cell
The highly conserved small GTPase Cdc42 regulates polarized cell growth and morphogenesis from yeast to humans. We previously reported that Cdc42 activation exhibits oscillatory dynamics at cell tips of Schizosaccharomyces pombe cells. Mathematical m
Autor:
Gennaro D'Urso, Valeria A. Copello, Ning Zhao, Laine Heidman, Kerry L. Burnstein, David J. Wiley, Stephanie Peacock, Fiorella Magani, Eric R. Bray, Maria J. Martinez
Publikováno v:
Molecular Systems Biology
Identifying critical pathways governing disease progression is essential for accurate prognosis and effective therapy. We developed a broadly applicable and novel systems‐level gene discovery strategy. This approach focused on constitutively active
Autor:
David J. Wiley, Mary Ellen Ahearn, Gennaro D'Urso, Jesse M. Hunter, Lisa Baumbach-Reardon, Chris Balak
Publikováno v:
F1000Research
Background:X-linked spinal muscular atrophy (XL-SMA) results from mutations in the Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1). Previously, four novel closely clustered mutations have been shown to cause this fatal infantile disorder affecting
Autor:
Dai Hirata, Maitreyi Das, Fulvia Verde, Marbelys Rodriguez Pino, Tetsuya Goshima, Illyce Nuñez, David J. Wiley, Chuan Chen, Kazunori Kume, Takashi Toda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6517ad7d2e171a814b43f1b210367de6
https://doi.org/10.7554/elife.14216.030
https://doi.org/10.7554/elife.14216.030
Autor:
Maitreyi Das, Marbelys Rodriguez Pino, David J. Wiley, Kazunori Kume, Dai Hirata, Fulvia Verde, Chuan Chen, Tetsuya Goshima, Takashi Toda, Illyce Nuñez
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
RNA-binding proteins contribute to the formation of ribonucleoprotein (RNP) granules by phase transition, but regulatory mechanisms are not fully understood. Conserved fission yeast NDR (Nuclear Dbf2-Related) kinase Orb6 governs cell morphogenesis in
Autor:
Fiorella Magani, Valeria A. Copello, Stephanie Peacock, Maria J. Martinez, Gennaro D'Urso, Eric R. Bray, Kerry L. Burnstein, David J. Wiley, Ning Zhao
Publikováno v:
Cancer Research. 78:A050-A050
Unbiased high-throughput approaches provide a global view of the massive genetic and transcriptomic changes that occur in and potentially drive cancer. Such approaches permit the discovery of novel networks that can serve as prognostic markers and th
Autor:
David J. Wiley, Maria J. Martinez, Eric R. Bray, Stephanie Peacock, Gennaro D'Urso, Kerry L. Burnstein, Valeria A. Copello, Fiorella Magani, Ning Zhao
Publikováno v:
Cancer Research. 78:1314-1314
Constitutively active androgen receptor (AR) splice variants such as AR-V7 represent a well-established mechanism of disease progression to castration-resistant prostate cancer (CRPC), the incurable form of PC. These AR variants lack the carboxyl-ter