Zobrazeno 1 - 10
of 64
pro vyhledávání: '"David J Welsh"'
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Cardiac magnetic resonance (CMR) imaging is used to assess the right ventricle (RV) of pulmonary hypertensive (PH) patients and more recently to track changes in response to therapy. We wished to investigate if repeat CMRs could be used to a
Externí odkaz:
https://doaj.org/article/deb67eb816ce413aa6049a8aba3b83eb
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary hypertension (PH) is a disease associated with vasoconstriction and remodelling of the pulmonary vasculature. Pulmonary artery fibroblasts (PAFs) play an important role in hypoxic-induced remodelling. Connexin 43 (Cx43) is involved in cellu
Externí odkaz:
https://doaj.org/article/59ba0b8e790446f59b541bcc24ffbc8e
Autor:
Kathryn S. Wilson, Hanna Buist, Kornelija Suveizdyte, John T. Liles, Grant R. Budas, Colin Hughes, Margaret R. MacLean, Martin Johnson, Alistair C. Church, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinas
Externí odkaz:
https://doaj.org/article/6525394d6a864924aa813898fecdb00f
Autor:
Geeshath Jayasekera, Kathryn S. Wilson, Hanna Buist, Rosemary Woodward, Aysel Uckan, Colin Hughes, Margaret Nilsen, A Colin Church, Martin K. Johnson, Lindsay Gallagher, James Mullin, Mandy R. MacLean, William M. Holmes, Andrew J. Peacock, David J. Welsh
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological feature
Externí odkaz:
https://doaj.org/article/16df05497cb345c3b63ec397451bbf19
Autor:
Lauren Brash, MD, Gareth D. Barnes, MD, Melanie J. Brewis, MD, A. Colin Church, MD, Simon J. Gibbs, MD, Luke S.G.E. Howard, MD, Geeshath Jayasekera, MBChB, Martin K. Johnson, MD, Neil McGlinchey, MBChB, Joelle Onorato, PhD, Joanne Simpson, MD, Colin Stirrat, MD, Stephen Thomson, MBChB, Geoffrey Watson, MD, Martin R. Wilkins, MD, Carrie Xu, MS, David J. Welsh, PhD, David E. Newby, MD, Andrew J. Peacock, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 176-186 (2018)
Summary: Apelin agonism causes systemic vasodilatation and increased cardiac contractility in humans, and improves pulmonary arterial hypertension (PAH) in animal models. Here, the authors examined the short-term pulmonary hemodynamic effects of syst
Externí odkaz:
https://doaj.org/article/dabac17dc7ae4c07888b359d538839c4
Autor:
Hanna Buist, Margaret Nilsen, Kathryn S. Wilson, Geeshath Jayasekera, A Colin Church, David J Welsh, Rosemary Woodward, Martin K Johnson, Lindsay Gallagher, Andrew J Peacock, Colin Hughes, Jim Mullin, William M. Holmes, Mandy MacLean, Aysel Uckan
Publikováno v:
Pulmonary Circulation
Pulmonary Circulation, Vol 10 (2020)
Pulmonary Circulation, Vol 10 (2020)
Cardiac magnetic resonance-derived ventricular variables are predictive of mortality in pulmonary arterial hypertension. Rodent models which emphasize ventricular function, allowing serial monitoring, are needed to identify pathophysiological feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e49bd41fc2d6f4d7525e2864841fe8
https://doi.org/10.1177/2045894019897513
https://doi.org/10.1177/2045894019897513
Autor:
Geeshath Jayasekera, Yvonne Dempsie, Jim Mullin, David J. Welsh, Lindsay Gallagher, Gerard Murphy
Publikováno v:
Pulmonary hypertension.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04dc7202dce7e224ba7fe893cdb98e46
https://doi.org/10.1183/13993003.congress-2020.1489
https://doi.org/10.1183/13993003.congress-2020.1489
Autor:
Andrew J. Peacock, Kathryn S. Wilson, Kornelija Suveizdyte, Grant R. Budas, Margaret R. MacLean, David J. Welsh, John T. Liles, Alistair C. Church, Hanna Buist, Martin Johnson, Colin Hughes
Publikováno v:
Pulmonary Circulation
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa877a96663605e15412df26612d6e38
http://europepmc.org/articles/PMC7235684
http://europepmc.org/articles/PMC7235684
Publikováno v:
Posters.
Background Cardiac magnetic resonance imaging (CMR) is the gold standard for assessing ventricular mass, volumes and function. Previous studies used both echocardiography and CMR to determine right ventricle (RV) response to pulmonary hypertension (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17db97a72f8a5db71648379026f8a56
https://doi.org/10.1136/heartjnl-2019-scf.12
https://doi.org/10.1136/heartjnl-2019-scf.12
Autor:
Lauren, Brash, Gareth D, Barnes, Melanie J, Brewis, A Colin, Church, Simon J, Gibbs, Luke S G E, Howard, Geeshath, Jayasekera, Martin K, Johnson, Neil, McGlinchey, Joelle, Onorato, Joanne, Simpson, Colin, Stirrat, Stephen, Thomson, Geoffrey, Watson, Martin R, Wilkins, Carrie, Xu, David J, Welsh, David E, Newby, Andrew J, Peacock
Publikováno v:
Jacc. Basic to Translational Science
Visual Abstract
Highlights • The effects of apelin on pulmonary hemodynamics in patients with PAH are unknown. • Systemic infusion caused a significant reduction in pulmonary vascular resistance and increase in cardiac output without a chang
Highlights • The effects of apelin on pulmonary hemodynamics in patients with PAH are unknown. • Systemic infusion caused a significant reduction in pulmonary vascular resistance and increase in cardiac output without a chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b60e50b89d94a0024b32c792d622a9f
https://pubmed.ncbi.nlm.nih.gov/29876530
https://pubmed.ncbi.nlm.nih.gov/29876530