Zobrazeno 1 - 10
of 57
pro vyhledávání: '"David J Sharkey"'
Autor:
Cottrell T Tamessar, Amanda L Anderson, Elizabeth G Bromfield, Natalie A Trigg, Shanmathi Parameswaran, Simone J Stanger, Judith Weidenhofer, Hui-Ming Zhang, Sarah A Robertson, David J Sharkey, Brett Nixon, John E Schjenken
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 3, Pp 1-20 (2024)
Seminal fluid extracellular vesicles (SFEVs) have previously been shown to interact with spermatozoa and influence their fertilisation capacity. Here, we sought to extend these studies by exploring the functional consequences of SFEV interactions wit
Externí odkaz:
https://doaj.org/article/383eea1f4ac24984a6676952ae206d05
Autor:
Kerrie L Foyle, David J Sharkey, Lachlan M Moldenhauer, Ella S Green, Jasmine J Wilson, Cassandra J Roccisano, M Louise Hull, Kelton P Tremellen, Sarah A Robertson
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 8, Pp n/a-n/a (2021)
Abstract Objectives Intravenous infusion of Intralipid is an adjunct therapy in assisted reproduction treatment (ART) when immune‐associated infertility is suspected. Here, we evaluated the effect of Intralipid infusion on regulatory T cells (Treg
Externí odkaz:
https://doaj.org/article/04b9ebf3fa284aedb4a96efc2a78db8d
Autor:
John E. Schjenken, David J. Sharkey, Ella S. Green, Hon Yeung Chan, Ricky A. Matias, Lachlan M. Moldenhauer, Sarah A. Robertson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Components of the seminal fluid are required for specific gene expression and immune changes in the uterus following mating, but the role that sperm play in this process has remained unclear. Here, John Schjenken et al. compare female mice mated to i
Externí odkaz:
https://doaj.org/article/84058944357844abadb2a9c35f93e128
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 264 (2022)
Oxidative stress and elevated levels of seminal and sperm reactive oxygen species (ROS) may contribute to up to 80% of male infertility diagnosis, with sperm ROS concentrations at fertilization important in the development of a healthy fetus and chil
Externí odkaz:
https://doaj.org/article/d1e4cab9d17843f0a1d2d1f57f930226
Autor:
Ella S. Green, Lachlan M. Moldenhauer, Holly M. Groome, David J. Sharkey, Peck Y. Chin, Alison S. Care, Rebecca L. Robker, Shaun R. McColl, Sarah A. Robertson
Publikováno v:
JCI Insight.
Publikováno v:
Andrology.
Autor:
Patience, Castleton, Prabin, Gyawali, Nicola, Mathews, Shadrack M, Mutuku, David J, Sharkey, Nicole O, McPherson
Publikováno v:
Andrology.
Oxidative stress in semen contributes up to 80% of all infertility diagnosis. Diagnostics to measure oxidative stress in semen was recently added to the 6To determine the natural fluctuations in semen redox indicators (MiOXSYSTotal, 118 repeat semen
Autor:
Alexandra Sorvina, Tetyana Shandala, Shudong Wang, David J. Sharkey, Emma Parkinson-Lawrence, Stavros Selemidis, Douglas A. Brooks
Publikováno v:
Cells, Vol 9, Iss 2, p 372 (2020)
Innate immunity is critical for host defence against pathogen and environmental challenge and this involves the production and secretion of immune mediators, such as antimicrobial peptides and pro-inflammatory cytokines. However, when dysregulated, i
Externí odkaz:
https://doaj.org/article/2ed70141493a4b60ab79fa37aeb8e94c
Autor:
Danielle J. Glynn, Kee Heng, Darryl L. Russell, David J. Sharkey, Sarah A. Robertson, Ravinder Anand-Ivell, Richard Ivell
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The hormone relaxin is important in female reproduction for embryo implantation, cardiovascular function, and during labor and lactation. Relaxin is also synthesized in males by organs of the male tract. We hypothesized that relaxin might be one comp
Externí odkaz:
https://doaj.org/article/0478aa2622d54f56bc3eb9c649e94780
Autor:
Kerrilyn R. Diener, Mark R. Hutchinson, Kenner C. Rice, Hanan H. Wahid, Lachlan M. Moldenhauer, Peck Yin Chin, Sarah A. Robertson, David J. Sharkey
Publikováno v:
Am J Pathol
Spontaneous preterm labor is frequently caused by an inflammatory response in the gestational tissues elicited by either infectious or sterile agents. In sterile preterm labor, the key regulators of inflammation are not identified, but platelet-activ