Zobrazeno 1 - 10
of 137
pro vyhledávání: '"David J Scurr"'
Autor:
Waraporn Suvannapruk, Leanne E Fisher, Jeni C Luckett, Max K Edney, Anna M Kotowska, Dong‐Hyun Kim, David J Scurr, Amir M Ghaemmaghami, Morgan R Alexander
Publikováno v:
Advanced Science, Vol 11, Iss 15, Pp n/a-n/a (2024)
Abstract A key goal for implanted medical devices is that they do not elicit a detrimental immune response. Macrophages play critical roles in the modulation of the host immune response and are the cells responsible for persistent inflammatory reacti
Externí odkaz:
https://doaj.org/article/b5cf615ac2274b8cbf84de8de62bd4aa
Autor:
Veeren M Chauhan, David J Scurr, Thomas Christie, Gary Telford, Jonathan W Aylott, David I Pritchard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0010531 (2022)
[This corrects the article DOI: 10.1371/journal.pntd.0005971.].
Externí odkaz:
https://doaj.org/article/741142fb8bae489dae2547b70350d5ea
Autor:
Veeren M Chauhan, David J Scurr, Thomas Christie, Gary Telford, Jonathan W Aylott, David I Pritchard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 12, p e0005971 (2017)
Necator americanus, a haematophagous hookworm parasite, infects ~10% of the world's population and is considered to be a significant public health risk. Its lifecycle has distinct stages, permitting its successful transit from the skin via the lungs
Externí odkaz:
https://doaj.org/article/39488ca46682497887be880ed7a39509
Autor:
Jack A. Bryant, Lily Riordan, Rowan Watson, Naa Dei Nikoi, Wioleta Trzaska, Louise Slope, Callum Tibbatts, Morgan R. Alexander, David J. Scurr, Robin C. May, Felicity de Cogan
Publikováno v:
Global Challenges, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract There is an increasing focus in healthcare environments on combatting antimicrobial resistant infections. While bacterial infections are well reported, infections caused by fungi receive less attention, yet have a broad impact on society and
Externí odkaz:
https://doaj.org/article/0989afacced74b4fafa69aa1a02248d2
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1011-1019
Hydrogel microneedles represent a promising approach to deliver drug molecules across skin into systemic circulation in a sustained release manner and without any polymer residue within skin. Acyclovir is an antiviral drug used for the treatment of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56e9c51d10c1df4b70c529a0e1072cb7
https://doi.org/10.1016/j.xphs.2022.11.012
https://doi.org/10.1016/j.xphs.2022.11.012
Autor:
Wenshi He, Max K. Edney, Simon M. L. Paine, Rian L. Griffiths, David J. Scurr, Ruman Rahman, Dong-Hyun Kim
Publikováno v:
Analytical Chemistry. 95:5994-6001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d716f56da9bb2f4ff464762fcec067b
https://doi.org/10.1021/acs.analchem.2c05807
https://doi.org/10.1021/acs.analchem.2c05807
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 571 (2022)
Historically, pre-clinical neuro-oncological drug delivery studies have exhaustively relied upon overall animal survival as an exclusive measure of efficacy. However, with no adopted methodology to both image and quantitate brain parenchyma penetrati
Externí odkaz:
https://doaj.org/article/f34ed7de76f3431c8b60fe5cb6cfd5a2
Autor:
Adelaide Jewell, Alice Brookes, Wanshan Feng, Marianne Ashford, Paul Gellert, James Butler, Peter M. Fischer, David J. Scurr, Michael J. Stocks, Pavel Gershkovich
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 174:29-34
Efficient delivery of highly lipophilic drugs or prodrugs to the mesenteric lymph nodes (MLN) can be achieved following oral administration with lipids. However, it remains unclear which specific MLN can be targeted and to what extent. Moreover, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b93d26d2026636aabadef77600dd0f6
https://doi.org/10.1016/j.ejpb.2022.03.014
https://doi.org/10.1016/j.ejpb.2022.03.014
Autor:
Max K. Edney, Wenshi He, Emily F. Smith, Edward Wilmot, Jacqueline Reid, Jim Barker, Rian L. Griffiths, Morgan R. Alexander, Colin E. Snape, David J. Scurr
Publikováno v:
The Analyst. 147:3854-3866
Carbonaceous deposits are ubiquitous, being formed on surfaces in engines, fuel systems and on catalysts operating at high temperatures for hydrocarbon transformations. In internal combustion engines, their formation negatively affects worldwide vehi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9872bae9ccaab23d848bd89c24231eb3
https://doi.org/10.1039/d2an00798c
https://doi.org/10.1039/d2an00798c
Autor:
Franziska Linke, James E. C. Johnson, Stefanie Kern, Christopher D. Bennett, Anbarasu Lourdusamy, Daniel Lea, Steven C. Clifford, Catherine L. R. Merry, Snow Stolnik, Morgan R. Alexander, Andrew C. Peet, David J. Scurr, Rian L. Griffiths, Anna M. Grabowska, Ian D. Kerr, Beth Coyle
Publikováno v:
Acta Neuropathologica Communications. 11
The most common malignant brain tumour in children, medulloblastoma (MB), is subdivided into four clinically relevant molecular subgroups, although targeted therapy options informed by understanding of different cellular features are lacking. Here, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e251f53016a2ccff96d184428c676568
https://doi.org/10.1186/s40478-022-01496-4
https://doi.org/10.1186/s40478-022-01496-4