Zobrazeno 1 - 10
of 54
pro vyhledávání: '"David J Schultz"'
Autor:
David J Schultz, Penn Muluhngwi, Negin Alizadeh-Rad, Madelyn A Green, Eric C Rouchka, Sabine J Waigel, Carolyn M Klinge
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184471 (2017)
MicroRNAs are biomarkers and potential therapeutic targets for breast cancer. Anacardic acid (AnAc) is a dietary phenolic lipid that inhibits both MCF-7 estrogen receptor α (ERα) positive and MDA-MB-231 triple negative breast cancer (TNBC) cell pro
Externí odkaz:
https://doaj.org/article/07cb3a0cd302491bb98637e0a57fc021
Publikováno v:
Frontiers in Microbiology, Vol 1 (2010)
The dependence of Protein Kinase A (PKA) activity on cAMP levels is an important facet of the dimorphic switch between budding and filamentous growth as well as for pathogenicity in some fungi. To better understand these processes in the pathogenic f
Externí odkaz:
https://doaj.org/article/2c2af290d77e4086b507a057f6ead194
Publikováno v:
Foods, Vol 13, Iss 17, p 2811 (2024)
Breast cancer remains a leading cause of death worldwide. The Apiaceae plant family includes many culinary spices that have been shown to have medicinal properties. Many phytochemicals exhibit potent bioactivities but often suffer from poor uptake an
Externí odkaz:
https://doaj.org/article/4a61bd3b777c4881b176a7d93c5b2e7f
Autor:
Su San Toh, Zehua Chen, Eric C. Rouchka, David J. Schultz, Christina A. Cuomo, Michael H. Perlin
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 2, Pp 505-518 (2018)
The successful interaction between pathogen/parasite and host requires a delicate balance between fitness of the former and survival of the latter. To optimize fitness a parasite/pathogen must effectively create an environment conducive to reproducti
Externí odkaz:
https://doaj.org/article/1fd4863673c74d6490ecd48e6b58a7e3
Autor:
Jaganathan Lakshmanan, Baochun Zhang, Kalen Wright, Amierreza T. Motameni, Vaitheesh L. Jaganathan, David J. Schultz, Carolyn M. Klinge, Brian G. Harbrecht
Publikováno v:
Journal of Functional Foods, Vol 64, Iss , Pp 103637- (2020)
Tender coconut water (TCW) is a natural plant product rich in phytochemicals and protects against toxic liver injury. However, the mechanism by which TCW inhibits inflammation and tissue damage is unknown. We examined the effect of TCW on primary rat
Externí odkaz:
https://doaj.org/article/81a97836f3ef4094af2bb24be3cc5722
Autor:
Carolyn M. Klinge, Chunyuan Chen, Albert R. Cunningham, Yoannis Imbert-Fernandez, Susan M. Dougherty, Susan M. Isaacs, Margarita M. Ivanova, Nalinie S. Wickramasinghe, David J. Schultz
Supplementary Data from Anacardic Acid Inhibits Estrogen Receptor α–DNA Binding and Reduces Target Gene Transcription and Breast Cancer Cell Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df0d8f6820a16c27ee6784988154a33
https://doi.org/10.1158/1535-7163.22485890.v1
https://doi.org/10.1158/1535-7163.22485890.v1
Autor:
Carolyn M. Klinge, Chunyuan Chen, Albert R. Cunningham, Yoannis Imbert-Fernandez, Susan M. Dougherty, Susan M. Isaacs, Margarita M. Ivanova, Nalinie S. Wickramasinghe, David J. Schultz
Anacardic acid (AnAc; 2-hydroxy-6-alkylbenzoic acid) is a dietary and medicinal phytochemical with established anticancer activity in cell and animal models. The mechanisms by which AnAc inhibits cancer cell proliferation remain undefined. AnAc 24:1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0773c400dd2b86f183017cc21ba5bb4c
https://doi.org/10.1158/1535-7163.c.6532127.v1
https://doi.org/10.1158/1535-7163.c.6532127.v1
Autor:
Margaret Wallen, Farrukh Aqil, Raghuram Kandimalla, Jeyaprakash Jeyabalan, Supipi Auwardt, Neha Tyagi, David J. Schultz, Wendy Spencer, Ramesh C. Gupta
Publikováno v:
Molecular Therapy - Nucleic Acids. 30:28-29
Emerging viral diseases, such as Ebola, SARS, MERS, and the pathogen causing COVID-19, SARS-CoV-2, present a challenge for the development of therapeutics because of strict biosafety handling procedures and rapid mutation of their genomes. To facilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3152f9cab0751165687bc891b99edb53
https://doi.org/10.1016/j.omtn.2022.09.002
https://doi.org/10.1016/j.omtn.2022.09.002
Autor:
William F. Paxton, Jesse L. Rozsa, Morgan M. Brooks, Mark P. Running, David J. Schultz, Jacek B. Jasinski, Hyun Jin Jung, Muhammad Zain Akram
Publikováno v:
Journal of Nanobiotechnology
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-8 (2021)
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-8 (2021)
Bio-inspired Topographically Mediated Surfaces (TMSs) based on high aspect ratio nanostructures have recently been attracting significant attention due to their pronounced antimicrobial properties by mechanically disrupting cellular processes. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8b01da95f86848aafaefc001494220
https://doi.org/10.1186/s12951-021-01218-3
https://doi.org/10.1186/s12951-021-01218-3
Autor:
Farrukh Aqil, Iqbal Ahmad, Jeyaprakash Jeyabalan, Ramesh C. Gupta, Radha Munagala, David J. Schultz
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6194, p 6194 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 12
International Journal of Molecular Sciences
Volume 22
Issue 12
Breast cancer (BC) is a leading cause of cancer deaths in women in less developed countries and the second leading cause of cancer death in women in the U.S. In this study, we report the inhibition of E2-mediated mammary tumorigenesis by Cuminum cymi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf7e0e6d874c82ed44db3680726a788
https://www.mdpi.com/1422-0067/22/12/6194
https://www.mdpi.com/1422-0067/22/12/6194