Zobrazeno 1 - 10
of 60
pro vyhledávání: '"David J O'Connell"'
Autor:
Ciara D Lynch, David J O'Connell
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0266921 (2022)
Deriving new value from waste streams through secondary processes is a central aim of the circular bioeconomy. In this study we investigate whether chemically defined spent media (CDSM) waste from cell culture bioprocess can be recycled and used as a
Externí odkaz:
https://doaj.org/article/f89b17c7538f401dbe36a08a715f3350
Publikováno v:
Applied Microbiology, Vol 4, Iss 2, Pp 959-971 (2024)
Spent fermentation media from bioprocessing represent a significant waste stream, and interest in recycling them as part of the developing circular bioeconomy is growing. The potential to reuse yeast spent culture media (YSM) to feed secondary bacter
Externí odkaz:
https://doaj.org/article/f8fa0df4ff494c2fad9de9d30393afb3
Autor:
Graham K Sheridan, Anita eWdowicz, Mark ePickering, Orla eWatters, Paul eHalley, Niamh eO'Sullivan, Claire eMooney, David J O'Connell, John J O'Connor, Keith J Murphy
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Several cytokines and chemokines are now known to play normal physiological roles in the brain where they act as key regulators of communication between neurons, glia and microglia. In particular, cytokines and chemokines can affect cardinal cellular
Externí odkaz:
https://doaj.org/article/69472af6fba742ddb8429bfdcbe8880a
Autor:
Vasiliki S Lalioti, Andrea Ilari, David J O'Connell, Elena Poser, Ignacio V Sandoval, Gianni Colotti
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85438 (2014)
Sorcin, a protein overexpressed in many multi-drug resistant cancers, dynamically localizes to distinct subcellular sites in 3T3-L1 fibroblasts during cell-cycle progression. During interphase sorcin is in the nucleus, in the plasma membrane, in endo
Externí odkaz:
https://doaj.org/article/98ccc40e4dd24fc0aa07dcae20e8ae3a
Autor:
Laura Murphy, David J. O’Connell
Publikováno v:
Fermentation, Vol 10, Iss 11, p 583 (2024)
The implementation of the circular bioeconomy is now widely accepted as a critical step towards reducing the environmental burden of industrial waste and reducing the impact of this waste on climate change. The valorisation of waste using microorgani
Externí odkaz:
https://doaj.org/article/c42a9acbfa9a4a5680246d5cb25e4198
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
The self-assembly of amyloid β peptide (Aβ) to fibrillar and oligomeric aggregates is linked to Alzheimer’s disease. Aβ binders may serve as inhibitors of aggregation to prevent the generation of neurotoxic species and for the detection of Aβ s
Publikováno v:
The CASE Journal, 2008, Vol. 4, Issue 2, pp. 3-19.
Externí odkaz:
http://www.emeraldinsight.com/doi/10.1108/TCJ-04-2008-B002
Publikováno v:
Breast Cancer Research and Treatment. 179:47-56
Triple-negative breast cancer (TNBC) currently lacks an approved targeted therapy. The tumour suppressor TP53 gene is mutated in approximately 80% of TNBC cases. COTI-2 is a third-generation thiosemicarbazone engineered for high efficacy and low toxi
Autor:
David J. O'Connell, Ciara D. Lynch
Deriving new value from waste streams through secondary processes is a central aim of the circular bioeconomy. In this study we investigate whether chemically defined spent media (CDSM) waste from cell culture bioprocess can be recycled and used as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba5bf7fcb720d6395df124ec4335203
https://doi.org/10.1101/2021.07.01.450323
https://doi.org/10.1101/2021.07.01.450323
Autor:
Wolfgang Winnicki, Sahra Pajenda, Sebastian Kapps, Florence Zawedde, Alice Schmidt, Ludwig Wagner, Daniela Gerges, David J. O'Connell
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259777 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259777 (2021)
PLoS ONE
Acute kidney injury (AKI) is an abrupt deterioration of renal function often caused by severe clinical disease such as sepsis, and patients require intensive care. Acute-phase parameters for systemic inflammation are well established and used in rout