Zobrazeno 1 - 10
of 86
pro vyhledávání: '"David J McMillan"'
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240834 (2020)
Bacterial "stand-alone" response regulators (RRs) are pivotal to the control of gene transcription in response to changing cytosolic and extracellular microenvironments during infection. The genome of group A Streptococcus (GAS) encodes more than 30
Externí odkaz:
https://doaj.org/article/86a381db554b4ba6b90e4cdb45ffa24e
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199163 (2018)
Bacteria respond to environmental changes through the co-ordinated regulation of gene expression, often mediated by two-component regulatory systems (TCS). Group A Streptococcus (GAS), a bacterium which infects multiple human body sites and causes mu
Externí odkaz:
https://doaj.org/article/6de468dd15fa480b891ab291aa41add6
Autor:
Celia McNeilly, Samantha Cosh, Therese Vu, Jemma Nichols, Anna Henningham, Andreas Hofmann, Anne Fane, Pierre R Smeesters, Catherine M Rush, Louise M Hafner, Natkuman Ketheesan, Kadaba S Sriprakash, David J McMillan
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156639 (2016)
The C-terminal region of the M-protein of Streptococcus pyogenes is a major target for vaccine development. The major feature is the C-repeat region, consisting of 35-42 amino acid repeat units that display high but not perfect identity. SV1 is a S.
Externí odkaz:
https://doaj.org/article/f9e3cbefbac745138d006e30595fc303
Autor:
Md Abu Choudhury, Nicole Marsh, Shahera Banu, David L Paterson, Claire M Rickard, David J McMillan
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146354 (2016)
Skin bacteria at peripheral intravenous catheter (PIVC) insertion sites pose a serious risk of microbial migration and subsequent colonisation of PIVCs, and the development of catheter related bloodstream infections (CRBSIs). Common skin bacteria are
Externí odkaz:
https://doaj.org/article/189161e5b6514f4681e778d5c863ac2a
Autor:
Ouli Xie, Jacqueline M. Morris, Andrew J. Hayes, Rebecca J. Towers, Magnus G. Jespersen, John A. Lees, Nouri L. Ben Zakour, Olga Berking, Sarah L. Baines, Glen P. Carter, Gerry Tonkin-Hill, Layla Schrieber, Liam McIntyre, Jake A. Lacey, Taylah B. James, Kadaba S. Sriprakash, Scott A. Beatson, Tadao Hasegawa, Phil Giffard, Andrew C. Steer, Michael R. Batzloff, Bernard W. Beall, Marcos D. Pinho, Mario Ramirez, Debra E. Bessen, Gordon Dougan, Stephen D. Bentley, Mark J. Walker, Bart J. Currie, Steven Y. C. Tong, David J. McMillan, Mark R. Davies
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an emerging cause of human infection with invasive disease incidence and clinical manifestations comparable to the closely related species, Streptococcus pyogenes. Through systematic ge
Externí odkaz:
https://doaj.org/article/64c2683511e049649c96119d191110c7
Autor:
David J McMillan, Santosh Y Kaul, P V Bramhachari, Pierre R Smeesters, Therese Vu, M G Karmarkar, Melkote S Shaila, Kadaba S Sriprakash
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e21346 (2011)
Infection of the skin or throat by Streptococcus dysgalactiae subspecies equisimilis (SDSE) may result in a number of human diseases. To understand mechanisms that give rise to new genetic variants in this species, we used multi-locus sequence typing
Externí odkaz:
https://doaj.org/article/248027237fb342a4b346e33253401f7d
Autor:
David J McMillan, Debra E Bessen, Marcos Pinho, Candace Ford, Gerod S Hall, José Melo-Cristino, Mário Ramirez
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11741 (2010)
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is an emerging global pathogen that can colonize and infect humans. Although most SDSE isolates possess the Lancefield group G carbohydrate, a significant minority have the group C carbohydrate
Externí odkaz:
https://doaj.org/article/7fa589065292453680b8099149b21e1d
Autor:
Adam S. Hamlin, Nicholas M. Andronicos, Ethan C Wilkinson, Catherine M Lobbe, Natkunam Ketheesan, Rukshan A M Rafeek, David J. McMillan, Kadaba S Sriprakash
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 2, Pp 151-161 (2021)
Animal Models and Experimental Medicine
Animal Models and Experimental Medicine
Background The neuropsychiatric disorders due to post‐streptococcal autoimmune complications such as Sydenham's chorea (SC) are associated with acute rheumatic fever and rheumatic heart disease (ARF/RHD). An animal model that exhibits characteristi
Autor:
Rukshan AM Rafeek, Adam S Hamlin, Nicholas M Andronicos, Craig S Lawlor, David J McMillan, Kadaba S Sriprakash, Natkunam Ketheesan
Publikováno v:
Immunology and cell biology. 100(8)
Group A streptococcal (GAS) infection is associated with a spectrum of autoimmune diseases including acute rheumatic fever/rheumatic heart disease (ARF/RHD) and neurobehavioral abnormalities. Antibodies against GAS M proteins cross-react with host ti
Publikováno v:
Pathology. 52:694-699
Invasive Streptococcus agalactiae (Group B streptococci, GBS) infections result in a large burden of disease globally. Changes in clinical and molecular epidemiology, as well as antibiotic resistance patterns, are being described globally amongst GBS