Zobrazeno 1 - 10
of 142
pro vyhledávání: '"David J Linden"'
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42194 (2012)
Functional hyperemia of the cerebral vascular system matches regional blood flow to the metabolic demands of the brain. One current model of neurovascular control holds that glutamate released by neurons activates group I metabotropic glutamate recep
Externí odkaz:
https://doaj.org/article/ffb8d01cae194e03b963632f5b00d2cd
Autor:
David J. Linden
A spirited collection of essays by cutting-edge neuroscientists that irreverently explores the quirky and counterintuitive aspects of brain function Neuroscientist David J. Linden approached leading brain researchers and asked each the same question:
Autor:
David J. Linden
You've probably seen it before: a human brain dramatically lit from the side, the camera circling it like a helicopter shot of Stonehenge, and a modulated baritone voice exalting the brain's elegant design in reverent tones.To which this book says: P
Autor:
Alexey V. Shevelkin, Chantelle E. Terrillion, Bagrat N. Abazyan, Tymoteusz J. Kajstura, Yan A. Jouroukhin, Gay L. Rudow, Juan C. Troncoso, David J. Linden, Mikhail V. Pletnikov
Publikováno v:
Neurobiology of Disease, Vol 103, Iss , Pp 144-153 (2017)
In addition to motor function, the cerebellum has been implicated in cognitive and social behaviors. Various structural and functional abnormalities of Purkinje cells (PCs) have been observed in schizophrenia and autism. As PCs express the gene Disru
Externí odkaz:
https://doaj.org/article/ca1f21a7b7144dda88c30d3c632f7a98
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1089-1097.e3 (2019)
Summary: The MEF2 family of transcription factors restricts excitatory synapse number in an activity-dependent fashion during development, yet MEF2 has not been implicated in long-term synaptic depression (LTD), which is thought to initiate synapse e
Externí odkaz:
https://doaj.org/article/51b7ae5285174b0396a6d1ba26e18a98
Autor:
Alexey V. Shevelkin, Chantelle E. Terrillion, Bagrat N. Abazyan, Tymoteusz J. Kajstura, Yan A. Jouroukhin, Gay L. Rudow, Juan C. Troncoso, David J. Linden, Mikhail V. Pletnikov
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 362- (2017)
Externí odkaz:
https://doaj.org/article/271fd185c4b54672a78be701bc88d89d
Autor:
David J. Linden
Publikováno v:
Neuron. 110(18)
A diagnosis of terminal cancer has caused me to think about my life in science and the delight and surprise it has brought me and the experiments I would pursue if I had just a bit more time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18d990efe8d4a8d5bd90a9f18743c15
https://pubmed.ncbi.nlm.nih.gov/36137520
https://pubmed.ncbi.nlm.nih.gov/36137520
Autor:
Gum Hwa Lee, Alena Savonenko, Paul F. Worley, Po Yu Chen, Susan M. Resnick, Bo Xiao, Joo Min Park, Kevin T. Chen, David J. Linden, Chan Hyun Na, Karen K. Szumlinski, Raozhou Lin, Lisa N. Learman, Akhilesh Pandey, Juan C. Troncoso, Santosh Renuse
Publikováno v:
Biological psychiatry, vol 89, iss 11
Background The serine-threonine kinase mTORC1 (mechanistic target of rapamycin complex 1) is essential for normal cell function but is aberrantly activated in the brain in both genetic-developmental and sporadic diseases and is associated with a spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49df03026079e55482ff5610fb55200
https://doi.org/10.1016/j.biopsych.2020.10.012
https://doi.org/10.1016/j.biopsych.2020.10.012
Autor:
Michael C. Reed, H. Frederik Nijhout, Beidi Qiang, Janet Best, Alyssa West, Rachel A. Saylor, Yunju Jin, Aya Abdalla, David J. Linden, Parastoo Hashemi, Edsel A. Peña
Publikováno v:
J Neurochem
It is important to monitor serotonin neurochemistry in the context of brain disorders. Specifically, a better understanding of biophysical alterations and associated biochemical functionality within subregions of the brain will enable better of under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40623afb99bf3687b3b80f09a3fd8104
https://doi.org/10.1111/jnc.14854
https://doi.org/10.1111/jnc.14854
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 39, iss 25
Surgical ovariectomy has been shown to reduce spine density in hippocampal CA1 pyramidal cells of rodents, and this reduction is reversed by 17β-estradiol (E2) treatment in a model of human estrogen replacement therapy. Here, we report reduction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9658f8a9ff87d57b3b100c1d595c5d6
https://doi.org/10.1523/jneurosci.2772-18.2019
https://doi.org/10.1523/jneurosci.2772-18.2019