Zobrazeno 1 - 10
of 58
pro vyhledávání: '"David J Jörg"'
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 7, Pp 436-440 (2022)
Abstract Erythropoietin deficiency is an extensively researched cause of renal anemia. The etiology and consequences of shortened red blood cell (RBC) life span in chronic kidney disease (CKD) are less well understood. Traversing capillaries requires
Externí odkaz:
https://doaj.org/article/4b877a9ec8904130a7a078a30c06124c
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010850 (2023)
Patients with renal anemia are frequently treated with erythropoiesis-stimulating agents (ESAs), which are dynamically dosed in order to stabilize blood hemoglobin levels within a specified target range. During typical ESA treatments, a fraction of p
Externí odkaz:
https://doaj.org/article/ccb441708a584dfbbe2497350d0b8f40
Autor:
David J Jörg, Doris H Fuertinger, Alhaji Cherif, David A Bushinsky, Ariella Mermelstein, Jochen G Raimann, Peter Kotanko
Publikováno v:
eLife, Vol 11 (2022)
For the treatment of postmenopausal osteoporosis, several drug classes with different mechanisms of action are available. Since only a limited set of dosing regimens and drug combinations can be tested in clinical trials, it is currently unclear whet
Externí odkaz:
https://doaj.org/article/cfa893961c024e1bb8eb730ff02f4a99
Autor:
Toshinori Nakagawa, David J. Jörg, Hitomi Watanabe, Seiya Mizuno, Seungmin Han, Tatsuro Ikeda, Yoshiki Omatsu, Keiko Nishimura, Miyako Fujita, Satoru Takahashi, Gen Kondoh, Benjamin D. Simons, Shosei Yoshida, Takashi Nagasawa
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109875- (2021)
Summary: In mouse testis, a heterogeneous population of undifferentiated spermatogonia (Aundiff) harbors spermatogenic stem cell (SSC) potential. Although GFRα1+ Aundiff maintains the self-renewing pool in homeostasis, the functional basis of hetero
Externí odkaz:
https://doaj.org/article/65978c133f0e40fea4fb9cba4e4d510d
Autor:
Gabriela Ferreira Dias, Nadja Grobe, Sabrina Rogg, David J. Jörg, Roberto Pecoits-Filho, Andréa Novais Moreno-Amaral, Peter Kotanko
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Red blood cells (RBC) are the most abundant cells in the blood. Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney f
Externí odkaz:
https://doaj.org/article/46a460344fa54812a04155b49ce70a18
Autor:
David J Jörg, Elizabeth E Caygill, Anna E Hakes, Esteban G Contreras, Andrea H Brand, Benjamin D Simons
Publikováno v:
eLife, Vol 8 (2019)
In living organisms, self-organised waves of signalling activity propagate spatiotemporal information within tissues. During the development of the largest component of the visual processing centre of the Drosophila brain, a travelling wave of proneu
Externí odkaz:
https://doaj.org/article/5522429ebf6349598cf5ed0127e55101
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Rhythmic patterning governs the formation of somites in vertebrates, but how the period of such rhythms can be changed is unclear. Here, the authors generate a genetic model in zebrafish to increase DeltaD expression, which increases the range of Del
Externí odkaz:
https://doaj.org/article/8ce0d90b0b2c48d99c95226f65c08231
Autor:
Lucas Wetzel, David J Jörg, Alexandros Pollakis, Wolfgang Rave, Gerhard Fettweis, Frank Jülicher
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171590 (2017)
Self-organized synchronization occurs in a variety of natural and technical systems but has so far only attracted limited attention as an engineering principle. In distributed electronic systems, such as antenna arrays and multi-core processors, a co
Externí odkaz:
https://doaj.org/article/524818f3c87340aa97a6d58e2d1530ef
Publikováno v:
Annual Review of Condensed Matter Physics. 12:135-153
This article reviews the physical principles of stem cell populations as active many-particle systems that are able to self-renew, control their density, and recover from depletion. We illustrate the dynamical and statistical hallmarks of homeostatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c00f1cde25c34c1a98f7da01692b2b
https://doi.org/10.1146/annurev-conmatphys-041720-125707
https://doi.org/10.1146/annurev-conmatphys-041720-125707