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pro vyhledávání: '"David J Herzfeld"'
Autor:
David J Herzfeld
Publikováno v:
eLife, Vol 13 (2024)
Abnormal activity in the cerebellar nuclei can be used to predict motor symptoms and induce them experimentally, pointing to potential therapeutic strategies.
Externí odkaz:
https://doaj.org/article/6d408ef6590141e4a425fed69b0915ca
Publikováno v:
eLife, Vol 9 (2020)
We provide behavioral evidence using monkey smooth pursuit eye movements for four principles of cerebellar learning. Using a circuit-level model of the cerebellum, we link behavioral data to learning’s neural implementation. The four principles are
Externí odkaz:
https://doaj.org/article/b8302b52dc3d4a40b06ae2716e08308e
Publikováno v:
J Neurophysiol
We evaluate existing spike sorters and present a new one that resolves many sorting challenges. The new sorter, called “full binary pursuit” or FBP, comprises multiple steps. First, it thresholds and clusters to identify the waveforms of all uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ce05433b5de01ba1084edcba6ffc50
https://doi.org/10.1152/jn.00047.2021
https://doi.org/10.1152/jn.00047.2021
We evaluate existing spike sorters and present a new one that resolves many sorting challenges. The new sorter, called “full binary pursuit” or FBP, comprises multiple steps. First, it thresholds and clusters to identify the waveforms of all uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d7f08d1694a9664957367a8d69ca20
https://doi.org/10.1101/2021.01.19.427297
https://doi.org/10.1101/2021.01.19.427297
Autor:
Lonneke Teunissen, Jihoon Jang, David J. Herzfeld, Koenraad Vandevoorde, Reza Shadmehr, Hannah R. Sheahan, Scott T. Albert
Publikováno v:
Nature Human Behaviour, 5, 7, pp. 920-934
Nature Human Behaviour, 5, 920-934
Nature Human Behaviour, 5, 920-934
Contains fulltext : 230178.pdf (Publisher’s version ) (Closed access) During extended motor adaptation, learning appears to saturate despite persistence of residual errors. This adaptation limit is not fixed but varies with perturbation variance; w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7b16e447288872877e0581962f31fd
https://hdl.handle.net/2066/230178
https://hdl.handle.net/2066/230178
Autor:
Reza Shadmehr, Oleg V. Komogortsev, Ehsan Sedaghat-Nejad, David J. Herzfeld, Thomas R. Reppert, Ioannis Rigas
Publikováno v:
Journal of Neurophysiology. 120:741-757
A common aspect of individuality is our subjective preferences in evaluation of reward and effort. The neural circuits that evaluate these commodities influence circuits that control our movements, raising the possibility that vigor differences betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a67e8a90261aa57d9f290895bc73c4
https://doi.org/10.1152/jn.00033.2018
https://doi.org/10.1152/jn.00033.2018
Publikováno v:
Nature neuroscience
The primary output cells of the cerebellar cortex, Purkinje cells, make kinematic predictions about ongoing movements via high-frequency simple spikes, but receive sensory error information about that movement via low-frequency complex spikes (CS). H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6f46f1e867206b86f21b25806ac14f
https://doi.org/10.1038/s41593-018-0136-y
https://doi.org/10.1038/s41593-018-0136-y
Autor:
Tara Palin, Kaveh Karbasi, Xiaoqin Wang, David J. Herzfeld, Paul Hage, Reza Shadmehr, Ehsan Sedaghat-Nejad
Publikováno v:
J Neurophysiol
The common marmoset (Callithrix Jacchus) is a promising new model for study of neurophysiological basis of behavior in primates. Like other primates, it relies on saccadic eye movements to monitor and explore its environment. Previous reports have de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509f7e232f8842ba1c1191723967e4b4
Publikováno v:
J Neurosci
Movements toward rewarding stimuli exhibit greater vigor, i.e., increased velocity and reduced reaction-times. This invigoration may be due to release of dopamine before movement onset. Dopamine release is strongly modulated by reward prediction erro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c100eb9bee77ec7722d23ff6aa41cfb0
https://europepmc.org/articles/PMC6670245/
https://europepmc.org/articles/PMC6670245/