Zobrazeno 1 - 10
of 614
pro vyhledávání: '"David J Harrison"'
Autor:
Peter Robinson, Chris M Bacon, Shujing J Lim, Abeer M Shaaban, Daniel Brierley, Ian Lewis, David J Harrison, Timothy J Kendall, Max Robinson
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 5, Pp 411-421 (2022)
Abstract The SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 Statement provides evidence‐based recommendations for the minimum content of clinical trial protocols. The Cellular Molecular Pathology Initiative, hosted
Externí odkaz:
https://doaj.org/article/d2ef50a8a70f4415a196cc411704705b
Autor:
Christina Fell, Mahnaz Mohammadi, David Morrison, Ognjen Arandjelović, Sheeba Syed, Prakash Konanahalli, Sarah Bell, Gareth Bryson, David J Harrison, David Harris-Birtill
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282577 (2023)
In this study we use artificial intelligence (AI) to categorise endometrial biopsy whole slide images (WSI) from digital pathology as either "malignant", "other or benign" or "insufficient". An endometrial biopsy is a key step in diagnosis of endomet
Externí odkaz:
https://doaj.org/article/12a3960a873c48b28ec011ad49cfb04a
Autor:
In Hwa Um, Lindesay Scott-Hayward, Monique Mackenzie, Puay Hoon Tan, Ravindran Kanesvaran, Yukti Choudhury, Peter D Caie, Min-Han Tan, Marie O'Donnell, Steve Leung, Grant D Stewart, David J Harrison
Publikováno v:
Journal of Pathology Informatics, Vol 11, Iss 1, Pp 35-35 (2020)
Background: Clinicopathological scores are used to predict the likelihood of recurrence-free survival for patients with clear cell renal cell carcinoma (ccRCC) after surgery. These are fallible, particularly in the middle range. This inevitably means
Externí odkaz:
https://doaj.org/article/fca157ad12a24eabb90b8fc5eaf2157c
Autor:
Pavlina Spiliopoulou, Farasat Kazmi, Francesca Aroldi, Thomas Holmes, David Thompson, Lucinda Griffiths, Cathy Qi, Matthew Parkes, Simon Lord, Gareth J. Veal, David J. Harrison, Vicky M. Coyle, Jill Graham, Thomas R. Jeffry Evans, Sarah P. Blagden
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Purpose 5-fluorouracil (5-FU) is inefficiently converted to the active anti-cancer metabolite, fluorodeoxyuridine-monophosphate (FUDR-MP), is associated with dose-limiting toxicities and challenging administration schedules. NUC-3373 is a ph
Externí odkaz:
https://doaj.org/article/8de199adb6da4ff4b44e74190f835493
Autor:
David J Harrison
Publikováno v:
International Review of Research in Open and Distributed Learning, Vol 16, Iss 1 (2015)
Online educational videos disseminated content for a university pre-service teacher internship program. Placed within an online course management system, the videos were accessed by 202 interns located in several Western U.S. states. To ascertain the
Externí odkaz:
https://doaj.org/article/b0dec187410741329f53a79cde0ad21b
Autor:
Romina Briffa, Inhwa Um, Dana Faratian, Ying Zhou, Arran K Turnbull, Simon P Langdon, David J Harrison
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144708 (2015)
Selecting colorectal cancer (CRC) patients likely to respond to therapy remains a clinical challenge. The objectives of this study were to establish which genes were differentially expressed with respect to treatment sensitivity and relate this to co
Externí odkaz:
https://doaj.org/article/74b1a424176f4992a898c67f787ce80d
Autor:
Angela Meade, Elena Frangou, Babak Choodari-Oskooei, James Larkin, Tom Powles, Grant D. Stewart, Laurence Albiges, Axel Bex, Toni K. Choueiri, Ian D. Davis, Tim Eisen, Alison Fielding, Craig Gedye, David J. Harrison, Rick Kaplan, Salena Mulhere, Paul Nathan, Grisma Patel, Jay Patel, Hannah Plant, Alastair Ritchie, Hannah Rush, Clare Shakeshaft, Martin R. Stockler, Cristina Suarez, Jemima Thompson, Nat Thorogood, Balaji Venugopal, Mahesh K.B. Parmar
Publikováno v:
Contemporary Clinical Trials Communications, Vol 42, Iss , Pp 101381- (2024)
Clinical trials to establish the efficacy of new agents in the adjuvant cancer setting typically take many years to complete. During that time, external factors can impact recruitment and reporting plans. An example is a new standard of care becoming
Externí odkaz:
https://doaj.org/article/152a532dd63f4c618fd32817ead311e1
Autor:
Dillum Patel, Alison L. Dickson, Greice M. Zickuhr, In Hwa Um, Oliver J. Read, Clarissa M. Czekster, Peter Mullen, David J. Harrison, Jennifer Bré
Publikováno v:
Translational Oncology, Vol 50, Iss , Pp 102114- (2024)
The combination of gemcitabine with platinum agents is a widely used chemotherapy regimen for a number of tumour types. Gemcitabine plus cisplatin remains the current therapeutic choice for biliary tract cancer. Gemcitabine is associated with multipl
Externí odkaz:
https://doaj.org/article/c3c62a6cd41e4e5e96928c106ddb18b1
Autor:
Rui Huang, Dana Faratian, Andrew H Sims, Danielle Wilson, Jeremy S Thomas, David J Harrison, Simon P Langdon
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94226 (2014)
Proteomic profiling of the estrogen/tamoxifen-sensitive MCF-7 cell line and its partially sensitive (MCF-7/LCC1) and fully resistant (MCF-7/LCC9) variants was performed to identify modifiers of endocrine sensitivity in breast cancer. Analysis of the
Externí odkaz:
https://doaj.org/article/077d26d1c05848e5befd2f3211436922
Autor:
Alexander Laird, Fiach C O'Mahony, Jyoti Nanda, Antony C P Riddick, Marie O'Donnell, David J Harrison, Grant D Stewart
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60483 (2013)
Renal cell carcinoma (RCC) is the most deadly of urological malignancies. Metastatic disease affects one third of patients at diagnosis with a further third developing metastatic disease after extirpative surgery. Heterogeneity in the clinical course
Externí odkaz:
https://doaj.org/article/a7361a2fec1345fa971f95bf8789058f