Zobrazeno 1 - 10
of 294
pro vyhledávání: '"David J Hackam"'
Autor:
Rachel Brower-Sinning, Diana Zhong, Misty Good, Brian Firek, Robyn Baker, Chhinder P Sodhi, David J Hackam, Michael J Morowitz
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e105046 (2014)
Previous studies of infant fecal samples have failed to clarify the role of gut bacteria in the pathogenesis of NEC. We sought to characterize bacterial communities within intestinal tissue resected from infants with and without NEC.26 intestinal sam
Externí odkaz:
https://doaj.org/article/8de9915209074673b3b961f8a2806bfb
Autor:
Zachariah Raouf, Steve N. Steinway, Daniel Scheese, Carla M. Lopez, Johannes W. Duess, Koichi Tsuboi, Maame Sampah, Daphne Klerk, Mahmoud El Baassiri, Hannah Moore, Cody Tragesser, Thomas Prindle, Jr., Sanxia Wang, Menghan Wang, Hee-Seong Jang, William B. Fulton, Chhinder P. Sodhi, David J. Hackam
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 53-70 (2024)
Background & Aims: The abdominal discomfort experienced by patients with colitis may be attributable in part to the presence of small intestinal dysmotility, yet mechanisms linking colonic inflammation with small-bowel motility remain largely unexplo
Externí odkaz:
https://doaj.org/article/4e2586e2cfd346c18313ac414ad157c4
Autor:
Matthew D Neal, Hongpeng Jia, Benjamin Eyer, Misty Good, Christopher J Guerriero, Chhinder P Sodhi, Amin Afrazi, Thomas Prindle, Congrong Ma, Maria Branca, John Ozolek, Jeffrey L Brodsky, Peter Wipf, David J Hackam
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65779 (2013)
Many inflammatory diseases may be linked to pathologically elevated signaling via the receptor for lipopolysaccharide (LPS), toll-like receptor 4 (TLR4). There has thus been great interest in the discovery of TLR4 inhibitors as potential anti-inflamm
Externí odkaz:
https://doaj.org/article/7ac61acca89f407e9b1fd71db80e98bf
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36560 (2012)
Recent evidence has implicated innate immunity in regulating neuronal survival in the brain during stroke and other neurodegenerations. Photoreceptors are specialized light-detecting neurons in the retina that are essential for vision. In this study,
Externí odkaz:
https://doaj.org/article/91b5d3e0ee354ba5bdaa32492320c109
Autor:
Johannes W. Duess, Maame E. Sampah, Carla M. Lopez, Koichi Tsuboi, Daniel J. Scheese, Chhinder P. Sodhi, David J. Hackam
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTNecrotizing enterocolitis (NEC) is a devastating disease in premature infants and the leading cause of death and disability from gastrointestinal disease in this vulnerable population. Although the pathophysiology of NEC remains incompletely
Externí odkaz:
https://doaj.org/article/f56af2fa1c104c2bac8316dca5920fef
Autor:
Maame Efua S. Sampah, David J. Hackam
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Prior to birth, the neonate has limited exposure to pathogens. The transition from the intra-uterine to the postnatal environment initiates a series of complex interactions between the newborn host and a variety of potential pathogens that persist ov
Externí odkaz:
https://doaj.org/article/a1c0ebfc26464ec3966675013808e0ca
Autor:
Chhinder P. Sodhi, Raheel Ahmad, Hongpeng Jia, William B. Fulton, Carla Lopez, Andres J. Gonzalez Salazar, Asuka Ishiyama, Maame Sampah, Steve Steinway, Sanxia Wang, Thomas Prindle, Menghan Wang, David L. Steed, Howard Wessel, Ziv Kirshner, Larry R. Brown, Peng Lu, David J. Hackam
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 323:G265-G282
Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in premature infants and is steadily rising in frequency. Patients who develop NEC have a very high mortality, illustrating the importance of developing novel
Publikováno v:
Current Treatment Options in Pediatrics. 8:278-294
Autor:
Chhinder P. Sodhi, Raheel Ahmad, William B. Fulton, Carla Lopez, Benjamin Eke, Daniel Scheese, Johannes Duess, Steven Steinway, Zachariah Raouf, Hannah Moore, Koichi Tsuboi, Maame Sampah, Hee-Seong Jang, Rachael H. Buck, David R. Hill, Grace M. Niemiro, Thomas Prindle, Sanxia Wang, Meghan Wang, Hongpeng Jia, Jonathan Catazaro, Peng Lu, David J. Hackam
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology.
Necrotizing enterocolitis (NEC) is the leading cause of morbidity and mortality in premature infants. One of the most devastating complications of NEC is the development of NEC-induced brain injury, which manifests as impaired cognition that persists
Autor:
David J. Hackam, Chhinder P. Sodhi
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 19:468-479