Zobrazeno 1 - 10
of 24
pro vyhledávání: '"David J Guckenberger"'
Autor:
Jennifer L Schehr, Zachery D Schultz, Jay W Warrick, David J Guckenberger, Hannah M Pezzi, Jamie M Sperger, Erika Heninger, Anwaar Saeed, Ticiana Leal, Kara Mattox, Anne M Traynor, Toby C Campbell, Scott M Berry, David J Beebe, Joshua M Lang
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159397 (2016)
Expression of programmed-death ligand 1 (PD-L1) in non-small cell lung cancer (NSCLC) is typically evaluated through invasive biopsies; however, recent advances in the identification of circulating tumor cells (CTCs) may be a less invasive method to
Externí odkaz:
https://doaj.org/article/8f6661b01ec84d04955efc3f9136e5d9
Autor:
Scott M Berry, Hannah M Pezzi, Eram D Williams, Jennifer M Loeb, David J Guckenberger, Alex J Lavanway, Alice A Puchalski, Cissy M Kityo, Peter N Mugyenyi, Franklin M Graziano, David J Beebe
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143631 (2015)
Viral load (VL) measurements are critical to the proper management of HIV in developing countries. However, access to VL assays is limited by the high cost and complexity of existing assays. While there is a need for low cost VL assays, performance m
Externí odkaz:
https://doaj.org/article/e27f0af4b9674333b40c80b2912e51a7
Autor:
Joshua M. Lang, Scott M. Berry, David J. Beebe, Philip J. Stephens, Scott M. Dehm, Lakeesha Carmichael, David J. Guckenberger, Benjamin K. Gibbs, Jacob Tokar, Stephanie M. Thiede, Erika Heninger, Sacha Horn, Zachery Chalmers, Benjamin P. Casavant, Allison Welsh, Lindsay N. Strotman, Jamie M. Sperger
This supplementary file contains additional Matierials and Methods detailing the VERSA process. Figure S1. Longitudinal analysis of capture efficiency of Epcam antibody. Figure S2. Multi-parametric analysis of gene expression, genomic profiling and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca5e0fa3cd3dead5194942679be1ba2
https://doi.org/10.1158/1078-0432.22465053
https://doi.org/10.1158/1078-0432.22465053
Autor:
Joshua M. Lang, Scott M. Berry, David J. Beebe, Philip J. Stephens, Scott M. Dehm, Lakeesha Carmichael, David J. Guckenberger, Benjamin K. Gibbs, Jacob Tokar, Stephanie M. Thiede, Erika Heninger, Sacha Horn, Zachery Chalmers, Benjamin P. Casavant, Allison Welsh, Lindsay N. Strotman, Jamie M. Sperger
Purpose: There is a critical clinical need for new predictive and pharmacodynamic biomarkers that evaluate pathway activity in patients treated with targeted therapies. A microscale platform known as VERSA (versatile exclusion-based rare sample analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e034db025c6058e5996b73db3a7aab3c
https://doi.org/10.1158/1078-0432.c.6525912
https://doi.org/10.1158/1078-0432.c.6525912
Publikováno v:
SLAS Technology. 26:80-91
Over the past decade, induced pluripotent stem cells (iPSCs) have become a major focus of stem cell and developmental biology research, offering researchers a clinically relevant source of cells that are amenable to genetic engineering approaches. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48aca359eb2bca597539efc90171aa9
https://doi.org/10.1177/2472630320921173
https://doi.org/10.1177/2472630320921173
Autor:
Xiaojing Su, Erwin Berthier, Ashleigh B. Theberge, Ashley M. Dostie, Ulri N. Lee, David J. Guckenberger, Tianzi Zhang
Publikováno v:
Lab on a Chip. 18:496-504
Microscale cell-based assays have demonstrated unique capabilities in reproducing important cellular behaviors for diagnostics and basic biological research. As these assays move beyond the prototyping stage and into biological and clinical research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dc50c198a33f6c41ec51651d6b62ca
https://doi.org/10.1039/c7lc01052d
https://doi.org/10.1039/c7lc01052d
Autor:
Jennifer L. Schehr, Sacha Horn, Anupama Singh, Charlotte N. Stahlfeld, David J. Beebe, Hannah M. Pezzi, Jacob Rothbauer, Zachery D. Schultz, Joshua M. Lang, Scott M. Berry, David J. Guckenberger, Rory M. Bade, Jamie M. Sperger
Publikováno v:
Lab on a Chip. 18:3446-3458
Rare cell populations provide a patient-centric tool to monitor disease treatment, response, and resistance. However, understanding rare cells is a complex problem, which requires cell isolation/purification and downstream molecular interrogation - p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0190c05f53968ada09209e3303f86ceb
https://doi.org/10.1039/c8lc00620b
https://doi.org/10.1039/c8lc00620b
Autor:
David J. Beebe, Mary C. Regier, Kevin Barrett, David J. Guckenberger, Hannah M. Pezzi, Kevin Fawcett, Scott M. Berry
Publikováno v:
Analytical Chemistry. 88:9902-9907
The simple, rapid magnetic manipulation of paramagnetic particles (PMPs) paired with the wide range of available surface chemistries has strongly positioned PMPs in the field of analyte isolation. One recent technology, sliding lid for immobilized dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80f491f9ffe507192001ea5da691390
https://doi.org/10.1021/acs.analchem.6b02257
https://doi.org/10.1021/acs.analchem.6b02257
Autor:
Charanjeet Kaur, David J. Beebe, Lauren M. Zasadil, Sean D. Ryan, David J. Guckenberger, Beth A. Weaver, Eric M. C. Britigan, Amy R. Moser
Publikováno v:
Molecular Biology of the Cell
Expression of a truncated allele of the Apc tumor suppressor causes intestinal tumors with a low rate of chromosomal instability (CIN). Increasing the rate of CIN suppresses tumor growth without inhibiting tumor initiation in both the small intestine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d69d67fd87ba70663669d40dd84274
https://doi.org/10.1091/mbc.e15-10-0747
https://doi.org/10.1091/mbc.e15-10-0747
Publikováno v:
SLAS Technology. 20:146-153
Cell based assays are essential tools utilized by research labs in a wide range of fields, including cell biology, toxicology, and natural product discovery labs, however in some situations the need for cell based assays does not justify the costs of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb77c38c3bff4a667cd734afd064deef
https://doi.org/10.1177/2211068214560609
https://doi.org/10.1177/2211068214560609