Zobrazeno 1 - 10
of 23
pro vyhledávání: '"David J Fitzhugh"'
Autor:
Matthew J Billard, David J Fitzhugh, Joel S Parker, Jaime M Brozowski, Marcus W McGinnis, Roman G Timoshchenko, D Stephen Serafin, Ruth Lininger, Nancy Klauber-Demore, Gary Sahagian, Young K Truong, Maria F Sassano, Jonathan S Serody, Teresa K Tarrant
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152856 (2016)
Triple negative breast cancer (TNBC) is a heterogeneous disease that has a poor prognosis and limited treatment options. Chemokine receptor interactions are important modulators of breast cancer metastasis; however, it is now recognized that quantita
Externí odkaz:
https://doaj.org/article/1ea3e1e80d024f64a99ff02f893eaede
Autor:
David J. Fitzhugh
Publikováno v:
Journal of Food Allergy. 4:60-64
Oral immunotherapy (OIT) involves the potential for a variety of adverse events, which range from serious systemic reactions that require epinephrine to minimal oral reactions that require no treatment. This chapter describes common types of reaction
Autor:
Richard L. Wasserman, Douglas H. Jones, Hugh H. Windom, Sakina S. Bajowala, Warner W. Carr, Thomas Chacko, Paul F. Detjen, Jennifer Fergeson, David J. Fitzhugh, Angela R. Hague, Jean Ly, Chad W. Mayer, Deanna M. Pence, Atul N. Shah
Publikováno v:
Annals of Allergy, Asthma & Immunology. 123:129-130.e3
Autor:
David J. Fitzhugh, M.W. McGinnis, Roman G. Timoshchenko, Joel S. Parker, Jaime M. Brozowski, D. Stephen Serafin, Nancy Klauber-DeMore, Jonathan S. Serody, G. Gary Sahagian, Young K. Truong, Ruth A. Lininger, Teresa K. Tarrant, Maria F. Sassano, Matthew J. Billard
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152856 (2016)
PLoS ONE
PLoS ONE
Triple negative breast cancer (TNBC) is a heterogeneous disease that has a poor prognosis and limited treatment options. Chemokine receptor interactions are important modulators of breast cancer metastasis; however, it is now recognized that quantita
Autor:
David J. Fitzhugh, David I. Bernstein
Publikováno v:
The journal of allergy and clinical immunology. In practice. 4(5)
Subcutaneous allergen immunotherapy (SCIT) clearly benefits appropriately selected patients with allergic rhinitis, asthma and anaphylaxis to stinging insects. Since inception of SCIT, systemic allergic reactions (SRs) and severe anaphylaxis have bee
Publikováno v:
Clinical Immunology. 128:66-74
Bromelain, a mixture of proteases derived from pineapple stem, has been reported to have therapeutic benefits in a variety of inflammatory diseases, including murine inflammatory bowel disease. The purpose of this work was to understand potential mec
Autor:
Samuel T Hwang, David J. Fitzhugh
Publikováno v:
Journal of Investigative Dermatology. 116:466-470
Although aberrations in adhesion molecule expression by lymphoma cells have been reported, the functional consequences of these changes are unclear. Herein, we report a patient with Sézary syndrome whose malignant peripheral blood T cells were TCRVb
Publikováno v:
The Journal of Immunology. 165:6677-6681
Memory T cells (mTC) express multiple chemokine receptors (including CCR4 and CCR6) that may potentially be involved in their arrest on inflamed endothelia. Herein, we specifically addressed whether CCR6 is required for mTC to arrest on TNF-α-activa
Autor:
Christine Tkaczyk, Alasdair M. Gilfillan, Elektra J. Papadopoulos, Dean D. Metcalfe, Samuel T Hwang, Christopher M. Sassetti, David J. Fitzhugh
Publikováno v:
European Journal of Immunology. 30:2355-2361
Mast cells (MC) are anatomically located near nerves and blood vessels in skin and the gastrointestinal tract and tend to localize within certain cutaneous tumors such as neurofibromas. However, the molecular mechanisms by which MC home to these site
Autor:
Thomas J. Schall, Samuel T Hwang, Tatsuyoshi Kawamura, Manisha A. Saraf, Nobuo Yamada, Hidehisa Saeki, Steven D. Rosen, Christopher M. Sassetti, Elektra J. Papadopoulos, David J. Fitzhugh, Andrew Blauvelt
Publikováno v:
European Journal of Immunology. 29:2551-2559
The lone CX3C chemokine, fractalkine (FK), is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. We now show that FK is associated with dendritic cells (DC)