Zobrazeno 1 - 10
of 58
pro vyhledávání: '"David J Berry"'
Autor:
Martin F Wilks, Ravindra Fernando, P L Ariyananda, Michael Eddleston, David J Berry, John A Tomenson, Nicholas A Buckley, Shaluka Jayamanne, David Gunnell, Andrew Dawson
Publikováno v:
PLoS Medicine, Vol 5, Iss 2, p e49 (2008)
Pesticide ingestion is a common method of self-harm in the rural developing world. In an attempt to reduce the high case fatality seen with the herbicide paraquat, a novel formulation (INTEON) has been developed containing an increased emetic concent
Externí odkaz:
https://doaj.org/article/7f19c5730cd743d69685dc6285c9fe5c
Autor:
James F. McCabe, Matthew T. Mulvee, Jonathan W. Steed, Stefanie Freitag-Pohl, Andrei S. Batsanov, David J. Berry, Katharina Edkins, Sten O. Nilsson Lill, Dmitry S. Yufit, Michael R. Probert, Jessica L. Andrews, David C. Apperley
Publikováno v:
Andrews, J L, Nielsson Lill, S O, Freitag-Pohl, S, Apperley, D, Yufit, D S, Batsanov, A S, Mulvee, M T, Edkins, K, McCabe, J F, Berry, D J, Probert, M R & Steed, J W 2021, ' Derisking the Polymorph Landscape: The Complex Polymorphism of Mexiletine Hydrochlorid ', Crystal Growth & Design, vol. 21, no. 12, pp. 7150–7167 . https://doi.org/10.1021/acs.cgd.1c01009
Crystal Growth & Design, 2021, Vol.21(12), pp.7150-7167 [Peer Reviewed Journal]
Crystal Growth & Design, 2021, Vol.21(12), pp.7150-7167 [Peer Reviewed Journal]
This work presents an updated solid-form discovery approach to the polymorphism of the antiarrhythmic drug mexiletine hydrochloride, in which experimental and computational techniques are combined to provide a rigorous characterization of the solid-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6c36f25318e5c2cfd9e2f75ac2e2372
https://pure.manchester.ac.uk/ws/files/205532675/Mexiletine_CGD_ref_revision_final.docx
https://pure.manchester.ac.uk/ws/files/205532675/Mexiletine_CGD_ref_revision_final.docx
Autor:
Beatriz Jiménez, Ash Salam, Matthias Witt, Luke Whiley, Matthew R. Lewis, Ada H Y Yuen, Zoltan Takats, Elena Chekmeneva, David J. Berry, Jeremy K. Nicholson, Humma Hussain
Publikováno v:
Analytical Chemistry
Annotation and identification of metabolite biomarkers is critical for their biological interpretation in metabolic phenotyping studies, presenting a significant bottleneck in the successful implementation of untargeted metabolomics. Here, a systemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bba7bd90835922cdf4defdd56f3da36
https://doi.org/10.1021/acs.analchem.9b00241
https://doi.org/10.1021/acs.analchem.9b00241
Autor:
Hongyu Zhou, David J. Berry, Hongwen Du, James F. McCabe, Antonio Llinas, Rafel Prohens, Philip Anthony Corner, Rafael Barbas
Publikováno v:
CrystEngComm. 20:1346-1351
Cocrystals have been identified as a method for ensuring the delivery of poorly soluble drugs. Development of cocrystal phases presents many challenges, with the in vivo drug delivery benefits difficult to predict robustly. Additional to this, many o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::195e8ae5fa3739426b9a01af3dcc0c1f
https://doi.org/10.1039/c7ce02059g
https://doi.org/10.1039/c7ce02059g
Autor:
David J. Berry, Melissa J. Goodwin, Benjamin William Steed, Dmitry S. Yufit, Jonathan W. Steed, Osama M. Musa
Publikováno v:
Crystal growth & design, 2017, Vol.17(10), pp.5552-5558 [Peer Reviewed Journal]
Povidone-iodine is a widely used antiseptic and on the World Health Organization’s List of Essential Medicines. We report the X-ray crystal structure of a two-monomer unit model compound showing that the structure of povidone-iodine comprises proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c59ce0aafb281b52a78d5f56563e106
https://doi.org/10.1021/acs.cgd.7b01103
https://doi.org/10.1021/acs.cgd.7b01103
Publikováno v:
Palliative Medicine
Background: Morphine can cause central nervous system side effects which impair driving skills. The legal blood morphine concentration limit for driving is 20 µg/L in France/Poland/Netherlands and 80 µg/L in England/Wales. There is no guidance as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64be59dcb698febbfa718d83677d73f3
https://pubmed.ncbi.nlm.nih.gov/29724154
https://pubmed.ncbi.nlm.nih.gov/29724154
Publikováno v:
Crystal growth & design, 2018, Vol.18(2), pp.701-709 [Peer Reviewed Journal]
The crystallization inhibitor polyvinylpyrrolidone (PVP) is commonly used as a stabilizer in the formation of amorphous polymer dispersions of poorly soluble pharmaceuticals. In this work we examine the use of a range of PVP-inspired small-molecule b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9356542485e27796d54f3f1623c321
http://dro.dur.ac.uk/23807/
http://dro.dur.ac.uk/23807/
Autor:
Katie E. Chappell, Simon Lovestone, Martin Raymond Green, Konstantina Spagou, David J. Berry, Olivier Cloarec, Matthew R. Lewis, Mark David, Paul Elliott, John C. Lindon, Elaine Holmes, Ada H Y Yuen, Verena Horneffer-van der Sluis, John P. Shockcor, Jeremy K. Nicholson, Zoltan Takats, Rachel Shaw, Anthony C. Dona, Jake T M Pearce
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c26de3ecd124d9b2f683f069ea3764
https://doi.org/10.1021/acs.analchem.6b01481
https://doi.org/10.1021/acs.analchem.6b01481
Autor:
Melissa J. Goodwin, Andrea Perrin, David J. Berry, Katharina Edkins, Jonathan W. Steed, Dmitry S. Yufit, Philip Anthony Corner, Osama M. Musa
Publikováno v:
Crystal growth & design, 2017, Vol.17(6), pp.3236-3249 [Peer Reviewed Journal]
Perrin, A, Goodwin, M J, Musa, O M, Berry, D J, Corner, P, Edkins, K, Yufit, D S & Steed, J W 2017, ' Hydration Behavior of Polylactam Clathrate Hydrate Inhibitors and Their Small-Molecule Model Compounds ', Crystal Growth and Design, vol. 17, no. 6, pp. 3236-3249 . https://doi.org/10.1021/acs.cgd.7b00221
Perrin, A, Goodwin, M J, Musa, O M, Berry, D J, Corner, P, Edkins, K, Yufit, D S & Steed, J W 2017, ' Hydration Behavior of Polylactam Clathrate Hydrate Inhibitors and Their Small-Molecule Model Compounds ', Crystal Growth and Design, vol. 17, no. 6, pp. 3236-3249 . https://doi.org/10.1021/acs.cgd.7b00221
The solution hydration behavior of a series of lactam-based kinetic clathrate hydrate inhibitors (KHIs) has been studied in order to determine mechanistic insight into their KHI performance. IR and 1H NMR spectroscopic titration data were compared ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f36488cc427e6def32690990b0e4339
http://dro.dur.ac.uk/21615/1/21615.pdf
http://dro.dur.ac.uk/21615/1/21615.pdf
Autor:
J. Jonathan Harburn, Robert A. Falconer, Caitlin A. Mooney, Mohit Jain, Jason H. Gill, David J. Berry, Paul M. Loadman, Steven L. Cobb
Publikováno v:
Journal of medicinal chemistry, 2017, Vol.60(10), pp.4496-4502 [Peer Reviewed Journal]
Matrix metalloproteinases (MMPs) are central to cancer development and metastasis. They are highly active in the tumour environment and absent or inactive in normal tissues; therefore they represent viable targets for cancer drug discovery. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4113e43402f45b856363f8acc45180
https://doi.org/10.1021/acs.jmedchem.6b01472
https://doi.org/10.1021/acs.jmedchem.6b01472