Zobrazeno 1 - 10
of 107
pro vyhledávání: '"David J, Williamson"'
Autor:
Tobias Starling, Irene Carlon-Andres, Maro Iliopoulou, Benedikt Kraemer, Maria Loidolt-Krueger, David J. Williamson, Sergi Padilla-Parra
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Simultaneous imaging of nine fluorescent proteins is demonstrated in a single acquisition using fluorescence lifetime imaging microscopy combined with pulsed interleaved excitation of three laser lines. Multicolor imaging employing genetical
Externí odkaz:
https://doaj.org/article/0da9e271dc724c688bf99fdcec5810b5
Autor:
David J. Williamson, Keith H. Nuechterlein, Todd Tishler, Joseph Ventura, Benjamin M. Ellingson, Ibrahim Turkoz, Richard S.E. Keefe, Larry Alphs
Publikováno v:
Schizophrenia Research: Cognition, Vol 30, Iss , Pp 100270- (2022)
Objective: Persons with schizophrenia exhibit greater neurocognitive test score dispersion. Here, we seek to characterize dispersion on the Neurocognitive Composite subtests of the Measurement of Treatment Research to Improve Cognition in Schizophren
Externí odkaz:
https://doaj.org/article/19df96c5526c40fd9d7ef4b01200ce4e
Autor:
Alan M. Szalai, Bruno Siarry, Jerónimo Lukin, David J. Williamson, Nicolás Unsain, Alfredo Cáceres, Mauricio Pilo-Pais, Guillermo Acuna, Damián Refojo, Dylan M. Owen, Sabrina Simoncelli, Fernando D. Stefani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Achieving high axial resolution is challenging in single-molecule localization microscopy. Here, the authors present a photometric method to decode the axial position of single molecules in a total internal reflection fluorescence microscope without
Externí odkaz:
https://doaj.org/article/6ad498979d8b41b29e474f3f28d8f096
Autor:
David J. Williamson, Garth L. Burn, Sabrina Simoncelli, Juliette Griffié, Ruby Peters, Daniel M. Davis, Dylan M. Owen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The characterization of clusters in single-molecule microscopy data is vital to reconstruct emerging spatial patterns. Here, the authors present a fast and accurate machine-learning approach to clustering, to address the issues related to the size of
Externí odkaz:
https://doaj.org/article/5bc574d8c2a043d098ecae44cf7959d5
Autor:
Daniel J. Nieves, Jeremy A. Pike, Florian Levet, David J. Williamson, Mohammed Baragilly, Sandra Oloketuyi, Ario de Marco, Juliette Griffié, Daniel Sage, Edward A. K. Cohen, Jean-Baptiste Sibarita, Mike Heilemann, Dylan M. Owen
Publikováno v:
Nature Methods. 20:259-267
This analysis compares the performance of seven algorithms for cluster analysis of single-molecule localization microscopy data. The results provide a framework for comparing these types of methods and point users to the best tools.
Single-molec
Single-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffce103240f0caded806d5e89497481
https://doi.org/10.1038/s41592-022-01750-6
https://doi.org/10.1038/s41592-022-01750-6
Autor:
Nisha K. Ramakrishnan, Helen M. Betts, Selena Milicevic Sephton, Xiaoyun Zhou, David J. Williamson, Stephen Sawiak, Franklin I. Aigbirhio
Publikováno v:
Nuclear Medicine and Biology. :71-77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fd4436ef3d879406f19db272bb8dfc
https://doi.org/10.1016/j.nucmedbio.2022.09.003
https://doi.org/10.1016/j.nucmedbio.2022.09.003
Autor:
Juliette Griffié, Leigh Shlomovich, David J. Williamson, Michael Shannon, Jesse Aaron, Satya Khuon, Garth L. Burn, Lies Boelen, Ruby Peters, Andrew P. Cope, Edward A. K. Cohen, Patrick Rubin-Delanchy, Dylan M. Owen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Single-molecule localisation microscopy (SMLM) allows the localisation of fluorophores with a precision of 10–30 nm, revealing the cell’s nanoscale architecture at the molecular level. Recently, SMLM has been extended to 3D, providing a
Externí odkaz:
https://doaj.org/article/e1603020fe654feab63ef71a07e8c512
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The particular HLA class I variants an individual carries influences their resistance and susceptibility to a multitude of diseases. Expression level and variation in the peptide binding region correlates with, for example, a person's progression to
Externí odkaz:
https://doaj.org/article/6e2fe6cbd21b4b69a9137aa702df7435
Autor:
Louis G. Jensen, Tjun Yee Hoh, David J. Williamson, Juliette Griffié, Daniel Sage, Patrick Rubin-Delanchy, Dylan M. Owen
Publikováno v:
Jensen, L G, Hoh, T Y, Williamson, D J, Griffié, J, Sage, D, Rubin-Delanchy, P & Owen, D M 2022, ' Correction of multiple-blinking artifacts in photoactivated localization microscopy ', Nature Methods, vol. 19, no. 5, pp. 594-602 . https://doi.org/10.1038/s41592-022-01463-w
Photoactivated localization microscopy (PALM) produces an array of localization coordinates by means of photoactivatable fluorescent proteins. However, observations are subject to fluorophore multiple blinking and each protein is included in the data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f400994d22494879e49b312305663ece
https://doi.org/10.1038/s41592-022-01463-w
https://doi.org/10.1038/s41592-022-01463-w
Autor:
Anna Oszmiana, David J. Williamson, Shaun-Paul Cordoba, David J. Morgan, Philippa R. Kennedy, Kevin Stacey, Daniel M. Davis
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 1957-1972 (2016)
Super-resolution microscopy has revealed that immune cell receptors are organized in nanoscale clusters at cell surfaces and immune synapses. However, mechanisms and functions for this nanoscale organization remain unclear. Here, we used super-resolu
Externí odkaz:
https://doaj.org/article/02afdb1a6f034e858c59ee75e79a8c7a