Zobrazeno 1 - 10
of 500
pro vyhledávání: '"David J, Weatherall"'
Autor:
Anuja P Premawardhena, ProfMD, Dileepa Senajith Ediriweera, PhD, Amir Sabouhanian, MSc, Angela Allen, PhD, David Rees, ProfMBBS, Shanthimala de Silva, MD, Windsor Perera, MD, Nimal Katugaha, MD, Mahinda Arambepola, MD, Robert C Yamashita, PhD, Sachith Mettananda, ProfDPhil, Nilam Jiffry, MD, Vikita Mehta, MD, Refai Cader, MD, Dayananda Bandara, MD, Timothy St Pierre, ProfPhD, Giulia Muraca, PhD, Christopher Fisher, PhD, Abirami Kirubarajan, MD, Shawn Khan, MD, Stephen Allen, ProfMD, Sanath P Lamabadusuriya, ProfPhD, David J Weatherall, ProfFRS, Nancy F Olivieri, ProfMD
Publikováno v:
The Lancet Global Health, Vol 10, Iss 1, Pp e134-e141 (2022)
Summary: Background: Worldwide, haemoglobin E β-thalassaemia is the most common genotype of severe β-thalassaemia. The paucity of long-term data for this form of thalassaemia makes evidence-based management challenging. We did a long-term observati
Externí odkaz:
https://doaj.org/article/a2e1b879a873459a9833330f12263bc7
Autor:
Shiromi Perera, Angela Allen, Ishari Silva, Menaka Hapugoda, M. Nirmali Wickramarathne, Indira Wijesiriwardena, Stephen Allen, David Rees, Dimitar G. Efremov, Christopher A. Fisher, David J. Weatherall, Anuja Premawardhena
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract β thalassaemia intermedia (βTI) are a heterogeneous group of disorders known to be extremely phenotypically diverse. This group is more complex to manage as no definitive treatment guidelines exist unlike for β thalassaemia major (βTM).
Externí odkaz:
https://doaj.org/article/6778d9b209994bc0ba59c70f57f95b78
Autor:
Angela Allen, Shiromi Perera, Luxman Perera, Rexan Rodrigo, Sachith Mettananda, Agnes Matope, Ishari Silva, Nizri Hameed, Christopher A. Fisher, Nancy Olivieri, David J. Weatherall, Stephen Allen, Anuja Premawardhena
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Introduction: The high frequencies of carriers of severe haemoglobinopathies and of iron deficiency in Southeast Asia require reliable and affordable tests to improve on current screening procedures.Objectives: We evaluate a “one stop” approach u
Externí odkaz:
https://doaj.org/article/2d30e2530cdb4a3cb214af3e58fd6ca2
Autor:
Anuja P Premawardhana, Rasnayaka Mudiyanse, Shamila T De Silva, Nilam Jiffry, Udaya Nelumdeniya, Udaya de Silva, Sanath P Lamabadusuriya, K Pushpakumara, Randima Dissanayaka, M Jansz, I Rifaya, Upul Navarathne, V Thirukumaran, Mahinda Arambepola, Wijesundara Dayanada Bandara, U Vaidyanatha, Devan Mendis, K Weerasekara, Nalika De Silva, D K Shantha Kumara, Sujeewa D Amarasena, K K Hemantha, M A C M Refai, Ishari Silva, Nizri Hameed, F Rajiyah, Sachith Mettananda, Angela Allen, David J Weatherall, Nancy F Oliveri
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220852 (2019)
ObjectivesOur aim was to describe the numbers and distribution of patients with different types of thalassemia and to assess the standards of care in all thalassemia treatment centers throughout Sri Lanka and the success of the ongoing prevention pro
Externí odkaz:
https://doaj.org/article/a7a803911fcf42efb6d434bb61b19f3e
Autor:
Sachith Mettananda, Anuja Premawardhena, Dayananda Bandara, Priya Chandrakumaran, Amir Sabouhanian, Nancy F. Olivieri, David J. Weatherall, Sanasi M. Jayawardena, Refai Cader, Shawn Khan, Angela Allen, Nila Thangavelu, Abirami Kirubarajan, Vikita Mehta
Publikováno v:
Acta Haematol
Background: Leg ulcers are a frequent complication in patients with the inherited hemoglobin disorders. In thalassemia, the literature is limited, and factors associated with the development of leg ulcers in hemoglobin E (HbE) beta thalassemia, the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445a6a6a4d76df5fc2316a4b6c06afc7
https://doi.org/10.1159/000520731
https://doi.org/10.1159/000520731
Autor:
Angela Allen, Stephen Allen, Rexan Rodrigo, Lakshman Perera, Wei Shao, Chao Li, Duolao Wang, Nancy Olivieri, David J Weatherall, Anuja Premawardhena
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188110 (2017)
BackgroundIron deficiency, the most common micronutrient disorder and cause of anaemia globally, impairs growth, cognition, behaviour and resistance to infection.Methods/resultsAs part of a national survey of inherited haemoglobin variants in 7526 st
Externí odkaz:
https://doaj.org/article/dfbee8e342db4847b84901e258defdff
Autor:
M. Arambepola, Sachith Mettananda, Anuja Premawardhena, Sanath P Lamabadusuriya, Nilam Jiffry, Windsor Perera, Stephen Allen, Nimal Katugaha, Vikita Mehta, Abirami Kirubarajan, Nancy F. Olivieri, Dayananda Bandara, Amir Sabouhanian, David C. Rees, Timothy G. St. Pierre, David J. Weatherall, Refai Cader, Dileepa Senajith Ediriweera, Robert C Yamashita, Shawn Khan, Shanthimala de Silva, Giulia Muraca, Chris Fisher, Angela Allen
Publikováno v:
The Lancet Global Health, Vol 10, Iss 1, Pp e134-e141 (2022)
BACKGROUND\ud Worldwide, haemoglobin E β-thalassaemia is the most common genotype of severe β-thalassaemia. The paucity of long-term data for this form of thalassaemia makes evidence-based management challenging. We did a long-term observational st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c2e873cf8ae2fc1271d2409b83925f
Autor:
M. Nirmali Wickramarathne, Dimitar G. Efremov, Chris Fisher, David C. Rees, Anuja Premawardhena, David J. Weatherall, Stephen Allen, S. Perera, Ishari Silva, Menaka Hapugoda, Indira Wijesiriwardena, Angela Allen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
β thalassaemia intermedia (βTI) are a heterogeneous group of disorders known to be extremely phenotypically diverse. This group is more complex to manage as no definitive treatment guidelines exist unlike for β thalassaemia major (βTM). There are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e5cdf4682054463a28f2d6c2a15f95
https://doaj.org/article/6778d9b209994bc0ba59c70f57f95b78
https://doaj.org/article/6778d9b209994bc0ba59c70f57f95b78
Autor:
Dr. Frédéric B Piel, PhD, Andrew J Tatem, PhD, Zhuojie Huang, PhD, Prof. Sunetra Gupta, PhD, Prof. Thomas N Williams, MRCP, Prof. David J Weatherall, FRS
Publikováno v:
The Lancet Global Health, Vol 2, Iss 2, Pp e80-e89 (2014)
Background: Changes in the geographical distribution of genetic disorders are often thought to happen slowly, especially when compared with infectious diseases. Whereas mutations, genetic drift, and natural selection take place over many generations,
Externí odkaz:
https://doaj.org/article/c2e59bca5d25447a8d5dce89a3462b13
Publikováno v:
PLoS Medicine, Vol 10, Iss 7, p e1001484 (2013)
BackgroundThe global burden of sickle cell anaemia (SCA) is set to rise as a consequence of improved survival in high-prevalence low- and middle-income countries and population migration to higher-income countries. The host of quantitative evidence d
Externí odkaz:
https://doaj.org/article/96e087f549b349b29aed3103af1d63e1