Zobrazeno 1 - 10
of 111
pro vyhledávání: '"David J, Reiss"'
Autor:
Eliza J.R. Peterson, Aaron N. Brooks, David J. Reiss, Amardeep Kaur, Julie Do, Min Pan, Wei-Ju Wu, Robert Morrison, Vivek Srinivas, Warren Carter, Mario L. Arrieta-Ortiz, Rene A. Ruiz, Apoorva Bhatt, Nitin S. Baliga
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112875- (2023)
Summary: The success of Mycobacterium tuberculosis (Mtb) is largely attributed to its ability to physiologically adapt and withstand diverse localized stresses within host microenvironments. Here, we present a data-driven model (EGRIN 2.0) that captu
Externí odkaz:
https://doaj.org/article/de11c15fd40b4b48ac4c29a3aacac4aa
Autor:
Matthew A. Wall, Serdar Turkarslan, Wei-Ju Wu, Samuel A. Danziger, David J. Reiss, Mike J. Mason, Andrew P. Dervan, Matthew W. B. Trotter, Douglas Bassett, Robert M. Hershberg, Adrián López García de Lomana, Alexander V. Ratushny, Nitin S. Baliga
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-15 (2021)
Abstract Despite recent advancements in the treatment of multiple myeloma (MM), nearly all patients ultimately relapse and many become refractory to multiple lines of therapies. Therefore, we not only need the ability to predict which patients are at
Externí odkaz:
https://doaj.org/article/8be0e48133514e37800ac2c098080257
Autor:
Samuel A Danziger, Mark McConnell, Jake Gockley, Mary H Young, Adam Rosenthal, Frank Schmitz, David J Reiss, Phil Farmer, Daisy V Alapat, Amrit Singh, Cody Ashby, Michael Bauer, Yan Ren, Kelsie Smith, Suzana S Couto, Frits van Rhee, Faith Davies, Maurizio Zangari, Nathan Petty, Robert Z Orlowski, Madhav V Dhodapkar, Wilbert B Copeland, Brian Fox, Antje Hoering, Alison Fitch, Katie Newhall, Bart Barlogie, Matthew W B Trotter, Robert M Hershberg, Brian A Walker, Andrew P Dervan, Alexander V Ratushny, Gareth J Morgan
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
BackgroundThe tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, wh
Externí odkaz:
https://doaj.org/article/48a59d8f2fb64baa9b747522459ffea9
Autor:
Serdar Turkarslan, Arjun V Raman, Anne W Thompson, Christina E Arens, Mark A Gillespie, Frederick von Netzer, Kristina L Hillesland, Sergey Stolyar, Adrian López García de Lomana, David J Reiss, Drew Gorman‐Lewis, Grant M Zane, Jeffrey A Ranish, Judy D Wall, David A Stahl, Nitin S Baliga
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 3, Pp 1-16 (2017)
Abstract Managing trade‐offs through gene regulation is believed to confer resilience to a microbial community in a fluctuating resource environment. To investigate this hypothesis, we imposed a fluctuating environment that required the sulfate‐r
Externí odkaz:
https://doaj.org/article/a655ac4e70d1467cac12e10d18846903
Autor:
Samuel A Danziger, David L Gibbs, Ilya Shmulevich, Mark McConnell, Matthew W B Trotter, Frank Schmitz, David J Reiss, Alexander V Ratushny
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224693 (2019)
Immune cell infiltration of tumors and the tumor microenvironment can be an important component for determining patient outcomes. For example, immune and stromal cell presence inferred by deconvolving patient gene expression data may help identify hi
Externí odkaz:
https://doaj.org/article/c210f3640b084ae4b0efafef16177ca4
Autor:
Brian A. Fox, Kathryn J. Newhall, Candice McCoy, Jeremy S. Abramson, Yeonhee Kim, Jerill Thorpe, David J. Reiss, Seamus P. Ragan, N. Eric Olson
Supplementary Methods; Supplementary Figures S1-S9; Supplementary Tables S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191b83d855590b5ceebe2e4af6e82262
https://doi.org/10.1158/1535-7163.22523172.v1
https://doi.org/10.1158/1535-7163.22523172.v1
Autor:
Peter J. O'Dwyer, Teng Jin Ong, Chrystal U. Louis, Larry Lyons, Sibabrata Banerjee, Rafia Bhore, Daniel W. Pierce, David J. Reiss, Thomas Lila, Hatem H. Soliman, Daniel Ricardo Carrizosa, Rishi Jain, Aparna Parikh, Martin Guiterrez, David M. Waterhouse, E. Gabriela Chiorean, Aparna Kaylan, Ben George, Edward J. Kim, Howard S. Hochster, Zev A. Wainberg
Baseline (screening) vs treatment cycle 2 (P=.06; paired t test). For patient 5, baseline data were not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd98b63eb49f579d01cbe44a0a85231
https://doi.org/10.1158/1078-0432.22475423
https://doi.org/10.1158/1078-0432.22475423
Autor:
Peter J. O'Dwyer, Teng Jin Ong, Chrystal U. Louis, Larry Lyons, Sibabrata Banerjee, Rafia Bhore, Daniel W. Pierce, David J. Reiss, Thomas Lila, Hatem H. Soliman, Daniel Ricardo Carrizosa, Rishi Jain, Aparna Parikh, Martin Guiterrez, David M. Waterhouse, E. Gabriela Chiorean, Aparna Kaylan, Ben George, Edward J. Kim, Howard S. Hochster, Zev A. Wainberg
Purpose:Assess safety and efficacy of nivolumab plus nab-paclitaxel and gemcitabine in patients with locally advanced/metastatic pancreatic cancer in a two-part, open-label, phase I trial.Patients and Methods:Fifty chemotherapy-naive patients receive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91944ff29f7b99aa8e56f618a1dd6950
https://doi.org/10.1158/1078-0432.c.6529076.v1
https://doi.org/10.1158/1078-0432.c.6529076.v1
Autor:
Peter J. O'Dwyer, Teng Jin Ong, Chrystal U. Louis, Larry Lyons, Sibabrata Banerjee, Rafia Bhore, Daniel W. Pierce, David J. Reiss, Thomas Lila, Hatem H. Soliman, Daniel Ricardo Carrizosa, Rishi Jain, Aparna Parikh, Martin Guiterrez, David M. Waterhouse, E. Gabriela Chiorean, Aparna Kaylan, Ben George, Edward J. Kim, Howard S. Hochster, Zev A. Wainberg
Percentage lymphocyte subset Ki67+. All patient visits are binned by treatment cycle. Data at baseline and treatment cycle 3 were compared using the Wilcoxon signed rank test. All available data are illustrated; however, statistical comparisons were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af451ccc2b3f88d0ca2643cefe85947
https://doi.org/10.1158/1078-0432.22475429
https://doi.org/10.1158/1078-0432.22475429
Autor:
Peter J. O'Dwyer, Teng Jin Ong, Chrystal U. Louis, Larry Lyons, Sibabrata Banerjee, Rafia Bhore, Daniel W. Pierce, David J. Reiss, Thomas Lila, Hatem H. Soliman, Daniel Ricardo Carrizosa, Rishi Jain, Aparna Parikh, Martin Guiterrez, David M. Waterhouse, E. Gabriela Chiorean, Aparna Kaylan, Ben George, Edward J. Kim, Howard S. Hochster, Zev A. Wainberg
T-Cell Tumor Infiltration in Tissue-Matched Baseline (screening) and On-Treatment Metastatic Tumors (arm B parts 1 and 2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5462aa83ef7e3c2c1c1145183bef1b4
https://doi.org/10.1158/1078-0432.22475426
https://doi.org/10.1158/1078-0432.22475426