Zobrazeno 1 - 10
of 271
pro vyhledávání: '"David J, Newman"'
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/5c1324af54ca43ef9bc0c3a24f81646e
Autor:
Saidanxia Amuti, Yohei Saito, Shuichi Fukuyoshi, Katsunori Miyake, David J. Newman, Barry R. O’Keefe, Kuo-Hsiung Lee, Kyoko Nakagawa-Goto
Publikováno v:
Molecules, Vol 29, Iss 3, p 651 (2024)
Eight vilasinin-class limonoids, including the unusually chlorinated rubescins K–M (1–3), the 2,3-epoxylated rubescin N (4), and rubescins O–R (5–8), were newly isolated from Trichilia rubescens. The structures of the isolated compounds were
Externí odkaz:
https://doaj.org/article/73427dc785014662bb22d080535fb349
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Eric J. Buenz, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 180, Iss , Pp 106207- (2022)
Externí odkaz:
https://doaj.org/article/b215426536d141999cb70e91b0a202d1
Autor:
Cherry L. Wainwright, Mauro M. Teixeira, David L. Adelson, Fernão C. Braga, Eric J. Buenz, Priscilla R.V. Campana, Bruno David, Keith B. Glaser, Yuka Harata-Lee, Melanie-Jayne R. Howes, Angelo A. Izzo, Pasquale Maffia, Alejandro M.S. Mayer, Claire Mazars, David J. Newman, Eimear Nic Lughadha, Rodrigo M. Pádua, Adriano M.C. Pimenta, John A.A. Parra, Zhipeng Qu, Hanyuan Shen, Michael Spedding, Jean-Luc Wolfender
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106076- (2022)
Drug discovery from natural sources is going through a renaissance, having spent many decades in the shadow of synthetic molecule drug discovery, despite the fact that natural product-derived compounds occupy a much greater chemical space than those
Externí odkaz:
https://doaj.org/article/7548a631600c45a6b94850aa79d2813e
Autor:
David J. Newman, DPhil
Publikováno v:
Current Therapeutic Research, Vol 95, Iss , Pp 100645- (2021)
ABSTRACT: For a significant number of years, scientists of many persuasions have assayed natural product materials ranging from crude extracts to pure compounds, in a multitude of assays causally related to some biological processes. However, in a ve
Externí odkaz:
https://doaj.org/article/d0ae1478e42f4b94849aed9671d3ea37
Autor:
David J. Newman
Publikováno v:
Current Pharmacology Reports. 9:67-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0cd74179b50e102358dfc9758f907f4
https://doi.org/10.1007/s40495-023-00313-3
https://doi.org/10.1007/s40495-023-00313-3
Autor:
Lesley-Ann Giddings, David J. Newman
Publikováno v:
Marine Drugs, Vol 20, Iss 1, p 62 (2022)
Marine environments are underexplored terrains containing fungi that produce a diversity of natural products given unique environmental pressures and nutrients. While bacteria are commonly the most studied microorganism for natural products in the ma
Externí odkaz:
https://doaj.org/article/09a4b5000f3f495287ac986d71b12b0a
Autor:
Alejandro MS. Mayer, Marsha Pierce, Maria Reji, Alex C. Wu, Karolina K. Jekielek, Henry Q. Le, Katelyn Howe, Maryam Butt, Sujin Seo, David J. Newman, Keith B. Glaser
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d170d566ef6ffa3e66f796fbb5eb8487
https://doi.org/10.1124/jpet.122.527010
https://doi.org/10.1124/jpet.122.527010
Publikováno v:
Nat Prod Rep
Covering: 1981 to 2019Natural products continue to play a major role in drug discovery, with half of new chemical entities based structurally on a natural product. Herein, we report a cheminformatic analysis of the structural and physicochemical prop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e8411051716d38a4b76301eb50afcb
https://doi.org/10.1039/d1np00039j
https://doi.org/10.1039/d1np00039j
Autor:
David J. Newman
Publikováno v:
Frontiers in Marine Science, Vol 5 (2018)
The initial sources of marine-derived compounds that on a small scale exhibited interesting biological activities, were often confined to collection levels ranging from
Externí odkaz:
https://doaj.org/article/5fe1700207b04eb5997cce0bffec9b04