Zobrazeno 1 - 10
of 32
pro vyhledávání: '"David J, McCanna"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Cytotoxicity testing is a regulatory requirement for safety testing of new ocular implants. In vitro toxicity tests determine whether toxic chemicals are present on a material surface or leach out of the material matrix. A method of evaluati
Externí odkaz:
https://doaj.org/article/7258330163dd48e3929b71c0caf17c44
Autor:
Yoshiyuki Kitamura, Yohei Mizuno, William Ngo, Katsuhide Yamasaki, Lyndon Jones, David J. McCanna
Publikováno v:
Contact Lens and Anterior Eye. 44:18-23
To determine the antimicrobial efficacy of a povidone-iodine system (PVP-I; cleadew, OPHTECS Corporation, Kobe, Japan), a peroxide system (AOSEPT Plus with HydraGlyde, Alcon, Fort Worth, TX), and a chemical multipurpose system (renu fresh, BauschLomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21d94056d3c4a8f20aef85a69b00ed4
https://doi.org/10.1016/j.clae.2020.02.012
https://doi.org/10.1016/j.clae.2020.02.012
Publikováno v:
Cutaneous and Ocular Toxicology. 39:370-379
Purpose To investigate the combined toxic effect of ultraviolet (UV) radiation and benzalkonium chloride (BAK), a common preservative in ophthalmic eye drops, on human corneal epithelial cells (HCEC). Methods Cultured HCEC were exposed to different c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3721150c1499ee49ebcb94f0b89822
https://doi.org/10.1080/15569527.2020.1833027
https://doi.org/10.1080/15569527.2020.1833027
Publikováno v:
Probiotics and Antimicrobial Proteins. 13:518-526
Antimicrobial peptides are polypeptides composed of less than 100 amino acids and are a class of antibiotics with strong activity against some infectious bacteria. This study examined the safety of four chosen antimicrobial peptides using primary hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88cc8a4c2aedc48800018a862de0197a
https://doi.org/10.1007/s12602-020-09692-1
https://doi.org/10.1007/s12602-020-09692-1
Publikováno v:
Journal of visualized experiments : JoVE. (179)
As the leading cause of blindness, cataracts are a significant burden for the tens of millions of people affected globally by this condition. Chemical exposures, among other environmental factors, are an established cause of cataracts. Ocular toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2164e22b96170e1f6f7567e25548cd
https://pubmed.ncbi.nlm.nih.gov/35068477
https://pubmed.ncbi.nlm.nih.gov/35068477
Autor:
Sarah Oh, Lakshman N. Subbaraman, Lyndon Jones, Maggie Miu Yee Kwan, David J. McCanna, Junghee Seo, Jaclyn M. L. Chang
Publikováno v:
Journal of visualized experiments : JoVE. (173)
This article describes the methods of measuring the toxicity of ultraviolet (UV) radiation and ocular toxins on primary (pHCEC) and immortalized (iHCEC) human corneal epithelial cell cultures. Cells were exposed to UV radiation and toxic doses of ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc7ed1005f57e7325af2263b9d43ea8
https://pubmed.ncbi.nlm.nih.gov/34369925
https://pubmed.ncbi.nlm.nih.gov/34369925
Publikováno v:
Scientific reports. 12(1)
Cytotoxicity testing is a regulatory requirement for safety testing of new ocular implants. In vitro toxicity tests determine whether toxic chemicals are present on a material surface or leach out of the material matrix. A method of evaluating the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4465d790f22175d9742c3004812f3872
https://pubmed.ncbi.nlm.nih.gov/35301374
https://pubmed.ncbi.nlm.nih.gov/35301374
Publikováno v:
Cutaneous and ocular toxicology. 40(2)
PURPOSE: Benzalkonium chloride (BAK) is a widely used disinfectant and preservative which is effective against a wide range of viruses (e.g. SARS-CoV and SARS-CoV-2), bacteria and fungi. However, it is toxic to the eye and skin. This study investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbd89d1acf359393f6733a27970076f
https://pubmed.ncbi.nlm.nih.gov/33771058
https://pubmed.ncbi.nlm.nih.gov/33771058
Publikováno v:
Probiotics and antimicrobial proteins. 13(2)
Antimicrobial peptides are polypeptides composed of less than 100 amino acids and are a class of antibiotics with strong activity against some infectious bacteria. This study examined the safety of four chosen antimicrobial peptides using primary hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d96e100ddbbf779d1d2b40811a64732
https://pubmed.ncbi.nlm.nih.gov/32748327
https://pubmed.ncbi.nlm.nih.gov/32748327
Publikováno v:
Contact lensanterior eye : the journal of the British Contact Lens Association. 44(5)
Several clinical studies have suggested that reusable silicone hydrogel contact lens materials exhibit a two-times increased rate of corneal infiltrative events compared to reusable hydrogels. One potential factor contributing to this complication re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440d1db7b2363547b7e30e04b4594696
https://pubmed.ncbi.nlm.nih.gov/33771440
https://pubmed.ncbi.nlm.nih.gov/33771440