Zobrazeno 1 - 10
of 360
pro vyhledávání: '"David J, Lederer"'
Autor:
Klaus F. Rabe, Fernando J. Martinez, Surya P. Bhatt, Tomotaka Kawayama, Borja G. Cosio, Robert M. Mroz, Maarten M. Boomsma, Helene Goulaouic, Michael C. Nivens, Michel Djandji, Xavier Soler, Ying Liu, Matthew P. Kosloski, Christine R. Xu, Nikhil Amin, Heribert Staudinger, David J. Lederer, Raolat M. Abdulai
Publikováno v:
ERJ Open Research, Vol 10, Iss 5 (2024)
Background Accumulating data implicate interleukin (IL)-33, a proinflammatory cytokine released locally upon epithelial cell damage, in the pathogenesis of COPD. In a phase 2 study, itepekimab, a human monoclonal antibody against IL-33, reduced exace
Externí odkaz:
https://doaj.org/article/3bd4edef6ab44bf1a5e1e7bec238bd0c
Autor:
Jonathan P. Singer, Carolyn S. Calfee, Kevin Delucchi, Joshua M. Diamond, Michaela A. Anderson, Luke A. Benvenuto, Ying Gao, Ping Wang, Selim M. Arcasoy, David J. Lederer, Steven R. Hays, Jasleen Kukreja, Aida Venado, Nicholas A. Kolaitis, Lorianna E. Leard, Rupal J. Shah, Mary Ellen Kleinhenz, Jeffrey Golden, Legna Betancourt, Michelle Oyster, Melanie Brown, Derek Zaleski, Nikhila Medikonda, Laurel Kalman, Priya Balar, Shreena Patel, Daniel R. Calabrese, John R. Greenland, Jason D. Christie
Publikováno v:
American Journal of Transplantation. 23:531-539
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78868f38a9a98c4f63ee01cd606d55f1
https://doi.org/10.1016/j.ajt.2023.01.020
https://doi.org/10.1016/j.ajt.2023.01.020
Autor:
Bina Choi, Steven M. Kawut, Ganesh Raghu, Eric Hoffman, Russell Tracy, Purnema Madahar, Elana J. Bernstein, R. Graham Barr, David J. Lederer, Anna Podolanczuk
Publikováno v:
ERJ Open Research, Vol 6, Iss 1 (2020)
High-attenuation areas (HAA) are a computed tomography-based quantitative measure of subclinical interstitial lung disease (ILD). We aimed to validate HAA in lung regions that are less subject to artefacts, such as extravascular lung water or depende
Externí odkaz:
https://doaj.org/article/34937b4f56a04d49b85f02c728411953
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background The diagnosis of idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILD) presents significant clinical challenges. To gain insights regarding the diagnostic experience of patients with ILD and to identify po
Externí odkaz:
https://doaj.org/article/010ab07552814cb6a58b11d9ec86fbda
Autor:
Ani Manichaikul, Xin-Qun Wang, Li Sun, Josée Dupuis, Alain C. Borczuk, Jennifer N. Nguyen, Ganesh Raghu, Eric A. Hoffman, Suna Onengut-Gumuscu, Emily A. Farber, Joel D. Kaufman, Dan Rabinowitz, Karen D. Hinckley Stukovsky, Steven M. Kawut, Gary M. Hunninghake, George R. Washko, George T. O’Connor, Stephen S. Rich, R. Graham Barr, David J. Lederer
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background We conducted a genome-wide association study (GWAS) of subclinical interstitial lung disease (ILD), defined as high attenuation areas (HAA) on CT, in the population-based Multi-Ethnic Study of Atherosclerosis Study. Methods We mea
Externí odkaz:
https://doaj.org/article/8569ea883b4e41909cc97d17bf6d172b
Autor:
Lawrence D. Sher, Michael E. Wechsler, Klaus F. Rabe, Jorge F. Maspero, Nadia Daizadeh, Xuezhou Mao, Benjamin Ortiz, Leda P. Mannent, Elizabeth Laws, Marcella Ruddy, Nami Pandit-Abid, Juby A. Jacob-Nara, Rebecca Gall, Paul J. Rowe, Yamo Deniz, David J. Lederer, Megan Hardin
Publikováno v:
Chest. 162:46-55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5dd3616c44d5755b2abf4b8500d7c9
https://doi.org/10.1016/j.chest.2022.01.071
https://doi.org/10.1016/j.chest.2022.01.071
Autor:
Kevin K Brown, Toby M Maher, Michael Kreuter, David J Lederer, Wim Wuyts, Nadia Verbruggen, Simone Stutvoet, Ann Fieuw, Paul Ford, Walid Abi-Saab, Marlies Wijsenbeek
Publikováno v:
BMJ Open Respiratory Research, Vol 6, Iss 1 (2019)
Introduction While current standard of care (SOC) for idiopathic pulmonary fibrosis (IPF) slows disease progression, prognosis remains poor. Therefore, an unmet need exists for novel, well-tolerated agents that reduce lung function decline and improv
Externí odkaz:
https://doaj.org/article/13f5f55143134d038a4aea43947c04e4
Autor:
Alexandros Strikoudis, Anna Cieślak, Lucas Loffredo, Ya-Wen Chen, Nina Patel, Anjali Saqi, David J. Lederer, Hans-Willem Snoeck
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3709-3723.e5 (2019)
Summary: The pathogenesis of idiopathic pulmonary fibrosis (IPF), an intractable interstitial lung disease, is unclear. Recessive mutations in some genes implicated in Hermansky-Pudlak syndrome (HPS) cause HPS-associated interstitial pneumonia (HPSIP
Externí odkaz:
https://doaj.org/article/8c6b0cd5fd3546ddab29c90e1d7b0188
Autor:
Brian E Cade, Han Chen, Adrienne M Stilp, Tin Louie, Sonia Ancoli-Israel, Raanan Arens, Richard Barfield, Jennifer E Below, Jianwen Cai, Matthew P Conomos, Daniel S Evans, Alexis C Frazier-Wood, Sina A Gharib, Kevin J Gleason, Daniel J Gottlieb, David R Hillman, W Craig Johnson, David J Lederer, Jiwon Lee, Jose S Loredo, Hao Mei, Sutapa Mukherjee, Sanjay R Patel, Wendy S Post, Shaun M Purcell, Alberto R Ramos, Kathryn J Reid, Ken Rice, Neomi A Shah, Tamar Sofer, Kent D Taylor, Timothy A Thornton, Heming Wang, Kristine Yaffe, Phyllis C Zee, Craig L Hanis, Lyle J Palmer, Jerome I Rotter, Katie L Stone, Gregory J Tranah, James G Wilson, Shamil R Sunyaev, Cathy C Laurie, Xiaofeng Zhu, Richa Saxena, Xihong Lin, Susan Redline
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1007739 (2019)
Sleep disordered breathing (SDB)-related overnight hypoxemia is associated with cardiometabolic disease and other comorbidities. Understanding the genetic bases for variations in nocturnal hypoxemia may help understand mechanisms influencing oxygenat
Externí odkaz:
https://doaj.org/article/c8e538632b9b471aacf35acd2dd1bf66
Autor:
Nikolaos G. Papadopoulos, Stanley J. Szefler, Leonard B. Bacharier, Jorge F. Maspero, Christian Domingo, Alessandro Fiocchi, Jason K. Lee, Nadia Daizadeh, David J. Lederer, Megan Hardin, Rebecca Gall, Michel Djandji, Shahid Siddiqui, Juby A. Jacob‐Nara, Yamo Deniz, Paul J. Rowe
Publikováno v:
Allergy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27f67df83c702bfcc2467cd16bf19aa
https://doi.org/10.1111/all.15743
https://doi.org/10.1111/all.15743