Zobrazeno 1 - 10
of 46
pro vyhledávání: '"David J, Girling"'
Publikováno v:
PharmacoEconomics. 24:443-452
Background: The use of granulocyte colony-stimulating factor (G-CSF) can enable dose intensification of chemotherapy in small-cell lung cancer (SCLC). However, given its acquisition cost, it is important to assess its cost effectiveness within a reso
Autor:
R J Sambrook, David J. Girling
Publikováno v:
British Journal of Cancer
Many chemotherapy regimens are used for treating SCLC in the United Kingdom, but it is not known, in any detail, which regimens are used, by which specialists, for which types of patient. We conducted a survey among all medical and clinical oncologis
Autor:
Penelope Hopwood, M G Bond, K. Moghissi, David J. Girling, Robert J. Sambrook, Richard Stephens
Publikováno v:
Clinical Oncology. 11:179-183
Symptoms of endotracheal or endobronchial obstruction caused by non-small cell lung cancer (NSCLC) may be relieved with external beam radiotherapy (XRT) or endobronchial treatment. The comparative roles of these two methods need to be established. Pa
Publikováno v:
British Journal of Cancer
The assessment of symptom palliation is an essential component of many treatment comparisons in clinical trials, yet an extensive literature search revealed no consensus as to its precise definition, which could embrace relief of symptoms, time to th
Autor:
A. Gregor, Lesley A. Stewart, Torri, J.P. Pignon, B Dautzenberg, Steven Piantadosi, Rodrigo Arriagada, Robert L. Souhami, M Wang, J.J. Lafitte, Sarah Burdett, Kovac, P. Rocmans, AH Brichet, Paul Van Houtte, M. K. B. Parmar, Richard Stephens, M Debevec, David J. Girling
Publikováno v:
The Lancet. 352:257-263
Background The role of postoperative radiotherapy in treatment of patients with completely resected non-small-cell lung cancer (NSCLC) remains unclear. We undertook a systematic review and meta-analysis of the available evidence from randomised trial
Autor:
Zhang Rugang, K Nygaard, David J. Girling, Mahesh K.B Parmar, S.J. Arnott, Lesley A. Stewart, B Launois, Jayne F. Tierney, Hanne Sand Hansen, Alain Roussel, Marc Gignoux, Wang Mei, G Spiliopoulos, W. Duncan
Publikováno v:
Europe PubMed Central
Purpose: The existing randomized evidence has failed to conclusively demonstrate the benefit or otherwise of preoperative radiotherapy in treating patients with potentially resectable esophageal carcinoma. This meta-analysis aimed to assess whether t
Autor:
D Gibson, Richard Stephens, A Harvey, Penelope Hopwood, M. K. B. Parmar, David J. Girling, J Davies
Publikováno v:
European Journal of Cancer. 34:49-57
We surveyed centres collaborating in two trials in lung cancer (LU12, LU13) and one in lung and head and neck cancer (CHART) to find out how QL questionnaires were being administered, with the aim of standardising procedures and improving compliance.
Autor:
Ann Cull, Ronald Stout, David J. Girling, Anna Gregor, Fergus Macbeth, John Yarnold, Richard Stephens, D. Machin, J A Kirkpatrick
Publikováno v:
European Journal of Cancer. 33:1752-1758
Prophylactic cranial irradiation (PCI) reduces the risk of cranial metastasis in small cell lung cancer (SCLC), but the magnitude and value of this reduction, the risks of radiation morbidity and whether PCI influences survival are unclear. We conduc
Publikováno v:
European Journal of Cancer. 33:20-28
Many clinical trials groups now routinely consider including Quality of Life (QoL) assessment in trials. Indeed, several have policies stating that QoL should be considered as a potential endpoint in all new trials and that if it is not to be evaluat
Autor:
David J Girling
Publikováno v:
The Lancet. 348:563-566
Summary Background Single-drug oral etoposide daily for 5 days or more in 3-week cycles is commonly used as palliative chemotherapy for small-cell lung cancer (SCLC). However, there have been no randomised trials to compare this treatment with standa