Zobrazeno 1 - 10
of 531
pro vyhledávání: '"David J, Brenner"'
Autor:
Ekaterina Royba, Igor Shuryak, Brian Ponnaiya, Mikhail Repin, Sergey Pampou, Charles Karan, Helen Turner, Guy Garty, David J. Brenner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In major radiological events, rapid assays to detect ionizing radiation exposure are crucial for effective medical interventions. The purpose of these assays is twofold: to categorize affected individuals into groups for initial treatments,
Externí odkaz:
https://doaj.org/article/600f4914a27c4250a926c76bb11ff824
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study explores the impact of densely-ionizing radiation on non-cancer and cancer diseases, focusing on dose, fractionation, age, and sex effects. Using historical mortality data from approximately 21,000 mice exposed to fission neutrons
Externí odkaz:
https://doaj.org/article/b7a0d39ce58042628a932c83236a22d7
Autor:
Evan L. Pannkuk, Evagelia C. Laiakis, Guy Garty, Sunil Bansal, Meth M. Jayatilake, Yuewen Tan, Brian Ponnaiya, Xuefeng Wu, Sally A. Amundson, David J. Brenner, Albert J. Fornace
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 35182-35196 (2024)
Externí odkaz:
https://doaj.org/article/c9ef3729879e4462a62c22eee403565f
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionTreating head and neck squamous cell carcinomas (HNSCC), especially human papillomavirus negative (HPV-) and locally advanced cases, remains difficult. Our previous analyses of radiotherapy-only HNSCC clinical trials data using mechanisti
Externí odkaz:
https://doaj.org/article/b5e94b5f84ce41f7838cfd1636ca9990
Autor:
Manuela Buonanno, Norman J. Kleiman, David Welch, Raabia Hashmi, Igor Shuryak, David J. Brenner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract An emerging intervention for control of airborne-mediated pandemics and epidemics is whole-room far-UVC (200–235 nm). Laboratory studies have shown that 222-nm light inactivates airborne pathogens, potentially without harm to exposed occup
Externí odkaz:
https://doaj.org/article/bce75f2641cb4c2785ebb3a68d12e95d
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The biological effects of densely-ionizing radiations such as neutrons and heavy ions encountered in space travel, nuclear incidents, and cancer radiotherapy, significantly differ from those of sparsely-ionizing photons and necessitate a com
Externí odkaz:
https://doaj.org/article/2cafb4268b3b428eb2f0fca131e355c8
Autor:
Igor Shuryak, Shanaz A. Ghandhi, Evagelia C. Laiakis, Guy Garty, Xuefeng Wu, Brian Ponnaiya, Emma Kosowski, Evan Pannkuk, Salan P. Kaur, Andrew D. Harken, Naresh Deoli, Albert J. Fornace, David J. Brenner, Sally A. Amundson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract There is a persistent risk of a large-scale malicious or accidental exposure to ionizing radiation that may affect a large number of people. Exposure will consist of both a photon and neutron component, which will vary in magnitude between i
Externí odkaz:
https://doaj.org/article/2d5470e0716145d4af6f52e648b8df37
Autor:
Shanaz A. Ghandhi, Shad R. Morton, Igor Shuryak, Younghyun Lee, Rajesh K. Soni, Jay R. Perrier, James Bakke, Janet Gahagan, Kim Bujold, Simon Authier, Sally A. Amundson, David J. Brenner, Denise Nishita, Polly Chang, Helen C. Turner
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Non-human primates, such as Rhesus macaques, are a powerful model for studies of the cellular and physiological effects of radiation, development of radiation biodosimetry, and for understanding the impact of radiation on human he
Externí odkaz:
https://doaj.org/article/e3eec020d628404887323c5ef5dd4b5f
Autor:
Igor Shuryak, Leah Nemzow, Bezalel A. Bacon, Maria Taveras, Xuefeng Wu, Naresh Deoli, Brian Ponnaiya, Guy Garty, David J. Brenner, Helen C. Turner
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract During a large-scale radiological event such as an improvised nuclear device detonation, many survivors will be shielded from radiation by environmental objects, and experience only partial-body irradiation (PBI), which has different consequ
Externí odkaz:
https://doaj.org/article/132213d2e1ce4c8a8ca0f85f20fbfa9b
Autor:
Guy Garty, Razib Obaid, Naresh Deoli, Ekaterina Royba, Yuewen Tan, Andrew D. Harken, David J. Brenner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The Radiological Research Accelerator Facility has modified a decommissioned Varian Clinac to deliver ultra-high dose rates: operating in 9 MeV electron mode (FLASH mode), samples can be irradiated at a Source-Surface Distance (SSD) of 20 cm
Externí odkaz:
https://doaj.org/article/02b7d8e2475a4e0db5ceb466ba9d3c5f