Zobrazeno 1 - 10 of 450 pro vyhledávání: '"David J, Bentrem"'
1
Akademický článek
Association of travel distance, surgical volume, and receipt of adjuvant chemotherapy with survival among patients with resectable lung cancerCentral MessagePerspective
Autor: Charles D. Logan, MD, Ryan J. Ellis, MD, MS, Joe Feinglass, PhD, Amy L. Halverson, MD, Diego Avella, MD, Kalvin Lung, MD, Samuel Kim, MD, Ankit Bharat, MBBS, Ryan P. Merkow, MD, MS, David J. Bentrem, MD, MS, David D. Odell, MD, MMSc
Publikováno v: JTCVS Open, Vol 13, Iss , Pp 357-378 (2023)
Objective: Regionalization of surgery for non–small cell lung cancer (NSCLC) to high-volume centers (HVCs) improves perioperative outcomes but frequently increases patient travel distance. Travel might decrease rates of adjuvant chemotherapy (AC) u
Externí odkaz: https://doaj.org/article/cfd6dbfd40a0456ba5c1eb6d01d16e80
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2
Akademický článek
Targeting BET Proteins Decreases Hyaluronidase-1 in Pancreatic Cancer
Autor: Krishan Kumar, Deepak Kanojia, David J. Bentrem, Rosa F. Hwang, Jonathan P. Butchar, Susheela Tridandapani, Hidayatullah G. Munshi
Publikováno v: Cells, Vol 12, Iss 11, p 1490 (2023)
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of dense stroma that is enriched in hyaluronan (HA), with increased HA levels associated with more aggressive disease. Increased levels of the HA-degrading enzymes h
Externí odkaz: https://doaj.org/article/329874e425a14a198be467a588f49b2d
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3
Akademický článek
Inhibition of MNKs promotes macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity
Autor: Thao N.D. Pham, Christina Spaulding, Mario A. Shields, Anastasia E. Metropulos, Dhavan N. Shah, Mahmoud G. Khalafalla, Daniel R. Principe, David J. Bentrem, Hidayatullah G. Munshi
Publikováno v: JCI Insight, Vol 7, Iss 9 (2022)
To elicit effective antitumor responses, CD8+ T cells need to infiltrate tumors and sustain their effector function within the immunosuppressive tumor microenvironment (TME). Here, we evaluate the role of MNK activity in regulating CD8+ T cell infilt
Externí odkaz: https://doaj.org/article/1a09d8a5ba8e4f9fab3e3efe9e16fad1
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5
Neoadjuvant therapy use and association with postoperative outcomes and overall survival in patients with extrahepatic cholangiocarcinoma
Autor: Casey M. Silver, Rachel H. Joung, Charles D. Logan, Al B. Benson, Devalingam Mahalingam, Michael I. D'Angelica, David J. Bentrem, Anthony D. Yang, Karl Y. Bilimoria, Ryan P. Merkow
Publikováno v: Journal of Surgical Oncology. 127:90-98
Evidence for neoadjuvant therapy (NAT) in extrahepatic cholangiocarcinoma (eCCA) is limited. Our objectives were to: (1) characterize treatment trends, (2) identify factors associated with receipt of NAT, and (3) evaluate associations between NAT and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a062b1f44a95ad51740ee0c1e811da
https://doi.org/10.1002/jso.27112
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