Zobrazeno 1 - 10
of 162
pro vyhledávání: '"David J, Anstee"'
Autor:
Deborah E. Daniels, Damien J. Downes, Ivan Ferrer-Vicens, Daniel C. J. Ferguson, Belinda K. Singleton, Marieangela C. Wilson, Kongtana Trakarnsanga, Ryo Kurita, Yukio Nakamura, David J. Anstee, Jan Frayne
Publikováno v:
Haematologica, Vol 109, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/4d782518f626402dbd7d20dbf0bff7ad
Autor:
Deborah E. Daniels, Daniel C.J. Ferguson, Rebecca E. Griffiths, Kongtana Trakarnsanga, Nicola Cogan, Katherine A. MacInnes, Kathryn E. Mordue, Tatyana Andrienko, Ivan Ferrer-Vicens, Daniel Ramos Jiménez, Phillip A. Lewis, Marieangela C. Wilson, Maurice A. Canham, Ryo Kurita, Yukio Nakamura, David J. Anstee, Jan Frayne
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 26-39 (2021)
Developing robust methodology for the sustainable production of red blood cells in vitro is essential for providing an alternative source of clinical-quality blood, particularly for individuals with rare blood group phenotypes. Immortalized erythroid
Externí odkaz:
https://doaj.org/article/1be556ed511b484ca9104a2782e6751a
Autor:
Tosti J. Mankelow, Belinda K. Singleton, Pedro L. Moura, Christian J. Stevens‐Hernandez, Nicola M. Cogan, Gyongyver Gyorffy, Sabine Kupzig, Luned Nichols, Claire Asby, Jennifer Pooley, Gabriella Ruffino, Faroakh Hosseini, Fiona Moghaddas, Marie Attwood, Alan Noel, Alex Cooper, David T. Arnold, Fergus Hamilton, Catherine Hyams, Adam Finn, Ashley M. Toye, David J. Anstee
Publikováno v:
eJHaem, Vol 2, Iss 2, Pp 175-187 (2021)
Abstract The SARS‐CoV‐2 virus causes COVID‐19, an infection capable of causing severe disease and death but which can also be asymptomatic or oligosymptomatic. We investigated whether ABO blood group or secretor status was associated with COVID
Externí odkaz:
https://doaj.org/article/b00501920a3741dfbd9b4677bea396f9
Autor:
Rachel A. Smith, Tosti J. Mankelow, Despoina Drizou, Thomas Bullock, Tom Latham, Sara Trompeter, Allison Blair, David J. Anstee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Sickle cell disease (SCD) is one of the most common inherited single gene disorders. Polymerisation of sickle hemoglobin results in erythrocytes that are inflexible and adherent, leading to coagulation, vascular and cellular activation and r
Externí odkaz:
https://doaj.org/article/80b26d17fb7b4680be25d1d650c7b9a6
Autor:
Nicole Thornton, Vanja Karamatic Crew, Louise Tilley, Carole A. Green, Chwen Ling Tay, Rebecca E. Griffiths, Belinda K. Singleton, Frances Spring, Piers Walser, Abdul Ghani Alattar, Benjamin Jones, Rosalind Laundy, Jill R. Storry, Mattias Möller, Lorna Wall, Richard Charlewood, Connie M. Westhoff, Christine Lomas-Francis, Vered Yahalom, Ute Feick, Axel Seltsam, Beate Mayer, Martin L. Olsson, David J. Anstee
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The molecular basis of the clinically important MAM blood group antigen present in most humans is unknown. We identify EMP3 as its encoding gene, establishing MAM as a new blood group system, and demonstrate the role of EMP3 in erythropoiesis through
Externí odkaz:
https://doaj.org/article/e938a7d9bc5f42fa84a3d130a0d92402
Autor:
Kongtana Trakarnsanga, Daniel Ferguson, Deborah E. Daniels, Rebecca E. Griffiths, Marieangela C. Wilson, Kathryn E. Mordue, Abi Gartner, Tatyana N. Andrienko, Annabel Calvert, Alison Condie, Angela McCahill, Joanne C. Mountford, Ashley M. Toye, David J. Anstee, Jan Frayne
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2019)
Abstract Background Pluripotent stem cells are attractive progenitor cells for the generation of erythroid cells in vitro as have expansive proliferative potential. However, although embryonic (ESC) and induced pluripotent (iPSC) stem cells can be in
Externí odkaz:
https://doaj.org/article/ab66fdf60c4c4d08878afa9f330cc664
Autor:
Deborah E. Daniels, Damien J. Downes, Ivan Ferrer-Vicens, Daniel C. J. Ferguson, Belinda K. Singleton, Marieangela C. Wilson, Kongtana Trakarnsanga, Ryo Kurita, Yukio Nakamura, David J. Anstee, Jan Frayne
Publikováno v:
Haematologica, Vol 105, Iss 8 (2020)
Externí odkaz:
https://doaj.org/article/45b08dbb99fb489a9a8511a89e4e0a31
Autor:
Joseph Hawksworth, Timothy J Satchwell, Marjolein Meinders, Deborah E Daniels, Fiona Regan, Nicole M Thornton, Marieangela C Wilson, Johannes GG Dobbe, Geert J Streekstra, Kongtana Trakarnsanga, Kate J Heesom, David J Anstee, Jan Frayne, Ashley M Toye
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 6, Pp 1-11 (2018)
Abstract Regular blood transfusion is the cornerstone of care for patients with red blood cell (RBC) disorders such as thalassaemia or sickle‐cell disease. With repeated transfusion, alloimmunisation often occurs due to incompatibility at the level
Externí odkaz:
https://doaj.org/article/9af938bdb64040d3b9bf6a27b7e9cbb8
Autor:
Kongtana Trakarnsanga, Rebecca E. Griffiths, Marieangela C. Wilson, Allison Blair, Timothy J. Satchwell, Marjolein Meinders, Nicola Cogan, Sabine Kupzig, Ryo Kurita, Yukio Nakamura, Ashley M. Toye, David J. Anstee, Jan Frayne
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The generation of a sustainable supply of erythroid progenitors is essential for the reliable production of anin vitroderived red blood cell clinical product. Here the authors immortalize early human erythroblasts to generate the first cell line capa
Externí odkaz:
https://doaj.org/article/43660dc1c27e4e12acb966c38920743b
Autor:
Pedro L. Moura, Bethan R. Hawley, Tosti J. Mankelow, Rebecca E. Griffiths, Johannes G.G. Dobbe, Geert J. Streekstra, David J. Anstee, Timothy J. Satchwell, Ashley M. Toye
Publikováno v:
Haematologica, Vol 103, Iss 12 (2018)
The process of maturation of reticulocytes into fully mature erythrocytes that occurs in the circulation is known to be characterized by a complex interplay between loss of cell surface area and volume, removal of remnant cell organelles and redundan
Externí odkaz:
https://doaj.org/article/e83ca56a8d8646e5aab645c91c80e34f