Výsledky vyhledávání

Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload

Publikováno v: Clinical Biochemistry. 50:911-917

Objective To assess the generation of reactive oxygen species (ROS) and the involvement of the main antioxidant pathways in low/intermediate-1-risk myelodysplastic syndromes (MDS) with iron overload (IOL). Methods We examined the levels of superoxide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a39fe3f11b242e1e49b574e8258fc8
https://doi.org/10.1016/j.clinbiochem.2017.05.018

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Akademický článek

Pinpointing change in virtual reality assisted treatment for violent offenders: a pilot study of Virtual Reality Aggression Prevention Training (VRAPT)

Autor: David Ivarsson, Carl Delfin, Pia Enebrink, Märta Wallinius

Publikováno v: Frontiers in Psychiatry, Vol 14 (2023)

Preventing relapse into violence and its destructive consequences among persistent re-offenders is a primary concern in forensic settings. The Risk-Need-Responsivity framework models the best current practice for offender treatment, focused on buildi

Externí odkaz: https://doaj.org/article/d43e188038f84e75902252ee7f887ddd

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A two-step approach for sequencing spliceosome-related genes as a complementary diagnostic assay in MDS patients with ringed sideroblasts

Autor: Mónica del Rey, Jesús María Hernández-Rivas, Fernando Ramos, María Hernández-Sánchez, María Abáigar, María Díez-Campelo, Alexander Kohlmann, Rocío Benito, Cristina Robledo, Alberto Valiente, Kamila Janusz, Consuelo del Cañizo, David Ivars, Rosa Collado

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
LEUKEMIA RESEARCH
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica

Our study aimed to analyze the presence of mutations in SF3B1 and other spliceosome-related genes in myelodysplastic syndromes with ringed sideroblasts (MDS-RS) by combining conventional Sanger and next-generation sequencing (NGS) methods, and to det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab09b7f8c316fa71da978e952714829
http://hdl.handle.net/10261/169236

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Increased Oxidative Damage Associated with Unfavorable Cytogenetic Subgroups in Chronic Lymphocytic Leukemia

Autor: David Ivars, Rosa Collado, Guillermo T. Sáez, Mercedes Egea, Á Miguel, Isabel Oliver, Carmen Tormos, Felix Carbonell

Publikováno v: BioMed Research International
BioMed Research International, Vol 2014 (2014)

Oxidative stress contributes to genomic instability in chronic lymphocytic leukemia (CLL), but its relationship with the acquisition of specific chromosomal abnormalities is unknown. We recruited 55 untreated CLL patients and assessed 8-oxo-2′-deox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74340273c19d5b55d82b82a30c47539f
https://doi.org/10.1155/2014/686392

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Early ROS-mediated DNA damage and oxidative stress biomarkers in Monoclonal B Lymphocytosis

Autor: Isabel Oliver, Silvia Borrego, Guillermo T. Sáez, Concha Cerdá, Felix Carbonell, Carmen Tormos, Mercedes Egea, Á Miguel, David Ivars, Rosa Collado

Publikováno v: CANCER LETTERS
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)

Monoclonal B Lymphocytosis (MBL) is defined as asymptomatic monoclonal B-cell expansion characterised by a CLL-phenotype, but with less than 5 x 10(9)/I circulating cells. Reactive oxygen species (ROS)-mediated cell damage plays a critical role in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96738dab0634207739139eaa3ad85de
https://doi.org/10.1016/j.canlet.2011.11.018

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Chromosome 8 Abnormalities (8p Losses and 8q Gains) in Patients with Chronic Lymphocytic Leukemia (CLL) and Del(17p)

Publikováno v: BLOOD
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
ResearcherID
Blood
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

Basis. Abnormalities in chromosome 8 (8p-/8q+) are observed in 2-5% of CLL patients. Microarray studies have revealed up to 30-40% of 8 alterations in del(17p) patients and an independent association with poor outcome. Large series assessing CLL pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d84bf7ee8bc6cf26241d32e6d600158
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=9714

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Application of FISH 7q in MDS patients without monosomy 7 or 7q deletion by conventional G-banding cytogenetics: does -7/7q- detection by FISH have prognostic value?

Publikováno v: LEUKEMIA RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica

Chromosomal abnormalities are detected in 40-60% of patients with de novo myelodysplastic syndromes (MDS). This study used the FISH technique in 773 patients with de novo MDS without evidence of monosomy 7 (-7) or 7q deletion (7q-) by conventional G-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf759fd9c782da383492f86c67cc3d78
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=2168

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Clinical and Biological Characterization of Patients with Low/Intermediate-1 Risk Myelodysplastic Syndrome and Iron Overload

Abstract 4956 Introduction. Patients with Myelodysplastic Syndrome (MDS) are susceptible to developing iron overload as a response to the red blood cell (RBC) transfusions and ineffective hematopoiesis. This iron overload (IOL) is characterized by an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aabd1dd5cba9bd491015ad00838da64
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=9718

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