Zobrazeno 1 - 10
of 34
pro vyhledávání: '"David I. Wilkinson"'
Publikováno v:
Experimental Dermatology. 7:179-183
Cultured normal human adult keratinocytes were exposed to (S)-(+)- camptothecin over the concentration range 10(-5) to 10(-10) M. The dose-dependent inhibition of growth was recorded using cell counting. The induction of terminal differentiation was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fda6667a81da59583704f4ccf439f09
https://doi.org/10.1111/j.1600-0625.1998.tb00321.x
https://doi.org/10.1111/j.1600-0625.1998.tb00321.x
Autor:
Julie A. Laxer, Dennis J. Carlo, Lawrence R. Smith, Marvin A. Karasek, Steven W. Brostoff, Helen H. Kurland, David I. Wilkinson, Lisa L. Caralli, Beverly J. Schwabe, Karen J. Froning, Chang Jennie C C
Publikováno v:
Annals of the New York Academy of Sciences. 756:370-381
Restricted T-cell receptor V beta gene use in animal models of autoimmune disease has led to the development of strategies to treat autoimmune disease by targeting the T-cell receptors of the pathogenic T-cells. Restricted T-cell receptor gene use ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd427625107ec799aee539a2d4227596
https://doi.org/10.1111/j.1749-6632.1995.tb44541.x
https://doi.org/10.1111/j.1749-6632.1995.tb44541.x
Publikováno v:
Journal of Investigative Dermatology. 100(2):132-136
Neuropeptides released in skin from nerve fibers may interact with endogenous growth factors (or other mitogenic agents) to induce psoriasis lesions characterized by proliferating epidermal keratinocytes. The mitogenic effects of two neuroeptides, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdfd6386efab0b15490da611f70cac5
Publikováno v:
Journal of the American Academy of Dermatology. 25:658-664
In each of 14 patients, two small but comparable psoriatic lesions were infused for 2 weeks with either saline or a saline solution of peptide T (as its analog D-ala1-peptide T amide) at 10(-7) mol/L with Alzet osmotic pumps worn extracorporeally. Du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef5c694b8ba13ed83f456d22fd1eccd
https://doi.org/10.1016/0190-9622(91)70249-2
https://doi.org/10.1016/0190-9622(91)70249-2
Publikováno v:
Skin Research and Technology. 1:41-43
Background/aims: Efficacy evaluation of new antipsoriatic drugs is difficult in the absence of good animal models. In the experimental treatment of psoriasis plaques, the administered dose of new drugs has to be kept at a minimum for safety reasons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7937258b8338d8ac71320efbcf8706ca
https://doi.org/10.1111/j.1600-0846.1995.tb00013.x
https://doi.org/10.1111/j.1600-0846.1995.tb00013.x
Publikováno v:
Experimental dermatology. 3(5)
Newborn foreskin and adult skin keratinocytes (KTs) were cultured in 24-well plates using keratinocyte basal medium (KBM) either alone or supplemented with epidermal growth factor (EGF) or nerve growth factor (NGF), plus one of the following: insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9c5d4b74101e6b8195acf9fb7e9282
https://pubmed.ncbi.nlm.nih.gov/7881770
https://pubmed.ncbi.nlm.nih.gov/7881770
Autor:
Eugene M. Farber, Dennis J. Carlo, Marvin A. Karasek, Karen J. Froning, Lawrence R. Smith, Beverly J. Schwabe, Kirsten K. Blumeyer, Steven W. Brostoff, David I. Wilkinson, Helen H. Kurland, Chang Jennie C C
Publikováno v:
Archives of Dermatology. 133:703
Background: We previously demonstrated a clonal dominance in the Vβ13.1 messages isolated from the lesional CD8 + T cells of psoriasis vulgaris, which suggested an interaction of Vβ13.1 + CD8 + T cells with skin antigens. Objectives: To determine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92edf4bc7fe92ebfa75083458e8b4f85
https://doi.org/10.1001/archderm.1997.03890420031004
https://doi.org/10.1001/archderm.1997.03890420031004
Autor:
Elaine K. Orenberg, David I. Wilkinson
Publikováno v:
Prostaglandins. 17:419-429
Ginea pig ear epidermal cells (keratinocytes) were established in primary cultures using trypsin, and treated in their proliferative phase of growth with prostaglandins E1, D1, F1 alpha, E2, D2, or F2 alpha. This phase is induced by the addition of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06885de699a811fa8741440e173969bd
https://doi.org/10.1016/s0090-6980(79)80010-6
https://doi.org/10.1016/s0090-6980(79)80010-6
Autor:
David I. Wilkinson
Publikováno v:
Journal of Investigative Dermatology. 63(4):350-355
Homogenates of newborn mouse skin were centrifuged at 900 × g , 15,000 × g , and 100,000 × g . Sediment from the last two centrifugations, as well as the 100,000 × g supernatant fraction incorporated [1- 14 C]-acetyl CoA and [1, 3- 14 C]-malonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1529a20b65ca2086dddd083b29b1fe4b
Publikováno v:
Journal of Investigative Dermatology. 77:385-388
Human newborn foreskin keratinocytes were maintained in culture in first passage for up to 60 days. An initial lag phase was followed by a growth and a final plateau phase. During this time, cell numbers, the morphologic appearance of both attached a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2e98dd443dc7bb658a7fd1f4de596e
https://doi.org/10.1111/1523-1747.ep12494554
https://doi.org/10.1111/1523-1747.ep12494554