Zobrazeno 1 - 10
of 69
pro vyhledávání: '"David I. Gottlieb"'
Autor:
Ling Wei, Lin Cui, B. Joy Snider, Mark Rivkin, Steven S. Yu, Chul-Sang Lee, Larry D. Adams, David I. Gottlieb, Eugene M. Johnson, Jr., Shan Ping Yu, Dennis W. Choi
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 183-193 (2005)
The study tested the hypothesis that transplantation of embryonic stem (ES) cells into rat cortex after a severe focal ischemia would promote structural repair and functional recovery. Overexpression of the human anti-apoptotic gene bcl-2 in ES cells
Externí odkaz:
https://doaj.org/article/8e78ac37e8ca46dab3700ce2b94cac92
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3946 (2008)
BACKGROUND: Oligodendrocytes are specialized cells of the nervous system that produce the myelin sheaths surrounding the axons of neurons. Myelinating the axons increases the speed of nerve conduction and demyelination contributes to the pathology of
Externí odkaz:
https://doaj.org/article/9a8cbc1147d1451ba05a04aba6d3a1ab
Publikováno v:
Stem Cells. 26:1841-1849
There is a need for improved methods to analyze transcriptional control of mammalian stem cell genes. We propose that embryonic stem cells (ESCs) will have broad utility as a model system, because they can be manipulated genetically and then differen
Publikováno v:
Stem Cells. 25:2235-2244
The goal of this research was to determine the effects of different growth factors on the survival and differentiation of murine embryonic stem cell-derived neural progenitor cells (ESNPCs) seeded inside of fibrin scaffolds. Embryoid bodies were cult
Autor:
Dennis W. Choi, Lin Cui, Eugene M. Johnson, Steven S. Yu, David I. Gottlieb, Chul-Sang Lee, Ling Wei, Mark Rivkin, B. Joy Snider, Larry D. Adams, Shan Ping Yu
Publikováno v:
Neurobiology of Disease, Vol 19, Iss 1, Pp 183-193 (2005)
The study tested the hypothesis that transplantation of embryonic stem (ES) cells into rat cortex after a severe focal ischemia would promote structural repair and functional recovery. Overexpression of the human anti-apoptotic gene bcl-2 in ES cells
Publikováno v:
Biochemical and Biophysical Research Communications. 327:155-162
Neural cells derived from ES cells in cell culture (ESNCs) have many of the properties of normal neural cells and provide a model of "neurogenesis-in-a-dish." Here we show that ESNCs provide a powerful system for analyzing neural gene transcription.
Autor:
Judith P. Golden, Lee Y. Tee, Brian A. Pierchala, B. Joy Snider, Chul Sang Lee, Dennis W. Choi, Susan Dusenbery, David I. Gottlieb, Toshihiro Takata, Eugene M. Johnson
Publikováno v:
Experimental Neurology. 191:65-76
Embryonic stem (ES) cells are genetically manipulable pluripotential cells that can be differentiated in vitro into neurons, oligodendrocytes, and astrocytes. Given their potential utility as a source of replacement cells for the injured nervous syst
Publikováno v:
Journal of Virology. 77:13203-13213
West Nile virus (WNV) infects neurons and leads to encephalitis, paralysis, and death in humans, animals, and birds. We investigated the mechanism by which neuronal injury occurs after WNV infection. Neurons in the anterior horn of the spinal cords o
Publikováno v:
Stem Cells. 21:41-49
Embryonic stem cells differentiate efficiently in culture into neural progenitors, neurons, oligodendrocytes, and astrocytes. An embryonic stem (ES) cell line with green fluorescent protein (GFP) inserted into the gene for Olig2, a lineage-specific t
Autor:
Derrick E. Rancourt, Gerard Bain, Jackie Hance, S.L. Rancourt, Teruhisa Tsuzuki, William J. Ray, David I. Gottlieb, A. Isogawa, Fiona C. Mansergh, Michael A. Wride, Y. Yoshimura
Publikováno v:
Functional & Integrative Genomics. 1:127-139
We have used a method for synchronously differentiating murine embryonic stem (ES) cells into functional neurons and glia in culture. Using subtractive hybridization we isolated approximately 1200 cDNA clones from ES cell cultures at the neural precu