Zobrazeno 1 - 10
of 53
pro vyhledávání: '"David I. Edwards"'
Autor:
Mark Farrington, D. R. Tucker, David I. Edwards, Hilary Humphreys, Georgia Duckworth, J. E. Coia, C. Fry, C. Mallaghan
Publikováno v:
Journal of Hospital Infection. 63:S1-S44
Meticillin-resistant Staphylococcus aureus (MRSA) remains endemic in many UK hospitals. Specific guidelines for control and prevention are justified because MRSA causes serious illness and results in significant additional healthcare costs. Guideline
Autor:
G L Ridgway, Kevin J. Towner, Derek F. J. Brown, Donald Morrison, Michael W. D. Wren, David I. Edwards, Peter M. Hawkey
Publikováno v:
Journal of Antimicrobial Chemotherapy. 56:1000-1018
These evidence-based guidelines have been produced after a literature review of the laboratory diagnosis and susceptibility testing of methicillin-resistant Staphylococcus aureus (MRSA). We have considered the detection of MRSA in screening samples a
Autor:
Peter J Jenks, David I. Edwards
Publikováno v:
International Journal of Antimicrobial Agents. 19:1-7
Modern triple drug regimens are highly effective for treating Helicobacter pylori infection, but bacterial resistance to one of the most effective antibiotics, metronidazole, is a serious and increasing problem. The activity of metronidazole in H. py
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:1973-1979
The β-lactam susceptibilities of 65 strains of Streptococcus pneumoniae for which penicillin MICs covered a broad range were assessed. The order of potency was amoxicillin (AMX) = amoxicillin-clavulanate (AMC) > penicillin G > cefpodoxime (CPO) > ce
Autor:
David I. Edwards, Mark A. Smith
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:347-353
Failure of triple-therapy regimes to eradicate Helicobacter pylori from the stomach is thought to be due to the occurrence of a metronidazole-resistant bacterial population. Exposure of metronidazole-resistant (MtzR) strains of H. pylori to an anaero
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 29:307-310
Purpose : The interaction between the constituent bases of deoxyribonucleic acid and the reduction products of the nitro-aromatic compound chloramphenicol and its nitroso derivative have been studied using an electrochemical system. Methods and Mater
Autor:
David I. Edwards
Publikováno v:
Journal of Antimicrobial Chemotherapy. 31:9-20
Publikováno v:
Free Radical Research Communications. 14:33-40
The electrochemical behaviour of three nitrofuran compounds, nitrofurazone, nitrofurantoin and furazolidone, has been studied in three solvent types; aprotic, aqueous and mixed, and at four working electrodes. Particular attention has focused on the
Publikováno v:
Biochemical Pharmacology. 40:1405-1410
The compound 3-amino-1,2,4-benzotriazine-1,4-dioxide, SR4233, has recently attracted considerable attention as a possible hypoxic cell radiation sensitizer and cytotoxic agent. The present study examines the influence of pH on the DNA damaging abilit
Publikováno v:
Inorganica Chimica Acta. 169:127-131
The compounds Rh 2 (O 2 CR) 4 ·2metronidazole (R = CH 3 (1); CH 2 CH 2 CH 2 Ph (2)) have been prepared by the reaction of Rh 2 (O 2 CR) 4 with an excess of metronidazole. The compounds have been characterized by analytical, spectroscopic, electroche